Biofunctionalized Graphene Quantum Dots Based Fluorescent Biosensor toward Efficient Detection of Small Cell Lung Cancer

2020 ◽  
Vol 3 (8) ◽  
pp. 4922-4932 ◽  
Author(s):  
Ashish Kalkal ◽  
Rangadhar Pradhan ◽  
Sachin Kadian ◽  
Gaurav Manik ◽  
Gopinath Packirisamy
Keyword(s):  
Lung Cancer ◽  
Quantum Dots ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Graphene Quantum Dots ◽  
Small Cell ◽  
Small Cell Lung ◽  
Fluorescent Biosensor ◽  
Efficient Detection

Tyrosine kinase inhibitor conjugated quantum dots for non-small cell lung cancer (NSCLC) treatment

2019 ◽  
Vol 133 ◽  
pp. 145-159 ◽  
Author(s):  
Nishant S. Kulkarni ◽  
Vineela Parvathaneni ◽  
Snehal K. Shukla ◽  
Leonard Barasa ◽  
Jeanette C. Perron ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Quantum Dots ◽  
Tyrosine Kinase ◽  
Small Cell Lung Cancer ◽  
Tyrosine Kinase Inhibitor ◽  
Cell Lung Cancer ◽  
Kinase Inhibitor ◽  
Small Cell ◽  
Small Cell Lung

scholarly journals CoFe2O4-Quantum Dots for Synergistic Photothermal/Photodynamic Therapy of Non-small-Cell Lung Cancer Via Triggering Apoptosis by Regulating PI3K/AKT Pathway

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Jingfeng Liu ◽  
Xiaoying Shi ◽  
Rongjun Zhang ◽  
Miaomiao Zhang ◽  
Juan He ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Quantum Dots ◽  
Photodynamic Therapy ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Reactive Oxygen Species Generation ◽  
Small Cell ◽  
Akt Pathway ◽  
Small Cell Lung ◽  
Therapy Effect

AbstractNon-small-cell lung cancer (NSCLC) has become the second most diagnosed malignant tumors worldwide. As our long-term interests in seeking nanomaterials to develop strategies of cancer therapies, we herein constructed novel CoFe2O4-quantum dots (QDs) with outstanding synergistic photothermal/photodynamic property which suppressed NSCLC efficiently without apparent toxicity. We showed that the combination of CoFe2O4-QDs + NIR treatment induces apoptosis of NSCLC cells. In addition, the CoFe2O4-QDs + NIR treatment also promotes reactive oxygen species generation to trigger cell death through regulating PI3K/AKT pathway. Moreover, the CoFe2O4-QDs + NIR treatment successfully eliminates tumor xenografts in vivo without apparent toxic effects. Taken together, we reported that the novel nanomaterials CoFe2O4-QDs could exhibit enhanced synergistic photothermal therapy and photodynamic therapy effect on killing NSCLC without toxicity, which could be a promising photosensitizer for NSCLC therapy.

Abstract #829: Effect of Body Mass Index (BMI) and Lipids on Non-Small Cell Lung Cancer (NSCLC) Survival

2016 ◽  
Vol 22 ◽  
pp. 176
Author(s):  
Genevieve Streb ◽  
Narjust Duma ◽  
Natasha Piracha ◽  
Sejal Kothadia ◽  
Komal Patel ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Body Mass Index ◽  
Small Cell Lung Cancer ◽  
Body Mass ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung
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