Cage-Monoterpenoid Quinoline Alkaloids with Neurite Growth Promoting Effects from the Fruits of Melodinus yunnanensis

2020 ◽  
Vol 22 (19) ◽  
pp. 7676-7680 ◽  
Author(s):  
Jing Wu ◽  
Si-Meng Zhao ◽  
Bao-Bao Shi ◽  
Mei-Fen Bao ◽  
Johann Schinnerl ◽  
...  
Keyword(s):  
Neurite Growth ◽  
Quinoline Alkaloids ◽  
Growth Promoting

scholarly journals STRAP and NME1 Mediate the Neurite Growth-Promoting Effects of the Neurotrophic Factor GDF5

iScience ◽  
2020 ◽  
Vol 23 (9) ◽  
pp. 101457
Author(s):  
Jayanth Anantha ◽  
Susan R. Goulding ◽  
Sean L. Wyatt ◽  
Ruth M. Concannon ◽  
Louise M. Collins ◽  
...  
Keyword(s):  
Neurotrophic Factor ◽  
Neurite Growth ◽  
Growth Promoting

161. A Pilot Screen for Neurite Growth-Promoting Compounds: A Comparison between Human iPS and Primary Rodent Neurons

2017 ◽  
Vol 81 (10) ◽  
pp. S67
Author(s):  
Anthony Harrington ◽  
Naomi Phillips ◽  
Grace Woodruff ◽  
Sean Purcell ◽  
Pascal Bonaventure ◽  
...  
Keyword(s):  
Neurite Growth ◽  
Growth Promoting

Neurite growth-promoting protein (amphoterin, p30) binds syndecan

1992 ◽  
Vol 200 (2) ◽  
pp. 444-451 ◽  
Author(s):  
Markku Salmivirta ◽  
Heikki Rauvala ◽  
Klaus Elenius ◽  
Markku Jalkanen
Keyword(s):  
Neurite Growth ◽  
Growth Promoting

scholarly journals Highly Enantioselective Catalytic Synthesis of Neurite Growth-Promoting Secoyohimbanes

2013 ◽  
Vol 20 (4) ◽  
pp. 500-509 ◽  
Author(s):  
Andrey P. Antonchick ◽  
Sara López-Tosco ◽  
Juan Parga ◽  
Sonja Sievers ◽  
Markus Schürmann ◽  
...  
Keyword(s):  
Neurite Growth ◽  
Catalytic Synthesis ◽  
Growth Promoting

scholarly journals Electric field-induced astrocyte alignment directs neurite outgrowth

2006 ◽  
Vol 2 (2) ◽  
pp. 93-103 ◽  
Author(s):  
JOHN K. ALEXANDER ◽  
BABETTE FUSS ◽  
RAYMOND J. COLELLO
Keyword(s):  
Electric Field ◽  
Neurite Outgrowth ◽  
Electric Fields ◽  
Neurite Growth ◽  
Spatial Arrangement ◽  
Electrical Field ◽  
Simple Method ◽  
Axonal Elongation ◽  
Rat Astrocytes ◽  
Growth Promoting

The extension and directionality of neurite outgrowth are key to achieving successful target connections during both CNS development and during the re-establishment of connections lost after neural trauma. The degree of axonal elongation depends, in large part, on the spatial arrangement of astrocytic processes rich in growth-promoting proteins. Because astrocytes in culture align their processes on exposure to an electrical field of physiological strength, we sought to determine the extent to which aligned astrocytes affect neurite outgrowth. To this end, dorsal root ganglia cells were seeded onto cultured rat astrocytes that were pre-aligned by exposure to an electric field of physiological strength (500 mV mm−1). Using confocal microscopy and digital image analysis, we found that neurite outgrowth at 24 hours and at 48 hours is enhanced significantly and directed consistently along the aligned astrocyte processes. Moreover, this directed neurite outgrowth is maintained when grown on fixed, aligned astrocytes. Collectively, these results indicate that endogenous electric fields present within the developing CNS might act to align astrocyte processes, which can promote and direct neurite growth. Furthermore, these results demonstrate a simple method to produce an aligned cellular substrate, which might be used to direct regenerating neurites.

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