Scocycamides, a Pair of Macrocyclic Dicaffeoylspermidines with Butyrylcholinesterase Inhibition and Antioxidation Activity from the Roots of Scopolia tangutica

2020 ◽  
Vol 22 (21) ◽  
pp. 8240-8244 ◽  
Author(s):  
Ji-Xia Wang ◽  
Yao-Peng Zhao ◽  
Na-Na Du ◽  
Yang Han ◽  
Hao Li ◽  
...  
Keyword(s):  
Antioxidation Activity ◽  
Butyrylcholinesterase Inhibition

Diterpenoid and phenolic contents of Sideritis hololeuca Boiss & Heldr. Apud Bentham with antioxidant and anticholinesterase activity

2020 ◽  
Vol 75 (5-6) ◽  
pp. 161-169
Author(s):  
Sema Carikci ◽  
Ahmet C. Goren ◽  
Turgut Kilic
Keyword(s):  
Essential Oil ◽  
Biological Activities ◽  
Reducing Power ◽  
Acetone Extract ◽  
Inhibition Activity ◽  
Phenolic Contents ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass ◽  
Main Component ◽  
Butyrylcholinesterase Inhibition

AbstractThe objective of this study is to determine essential oil, diterpenoid and phenolic contents of Sideritis hololeuca along with their biological activities. Phytol was found to be the main component of the essential oil. Seven known kaurane diterpenoids, siderol (140 mg, 0.16%, w/w), 7-acetoxy sideroxol (15 mg, 0.02%, w/w), eubol (6 mg, 0.01%, w/w), eubotriol (5 mg, 0.03%, w/w), 7-epicandicandiol (3 mg, 0.02%, w/w), ent-7α-acetoxy-18-hydroxykaur-16-ene (5 mg, 0.01%, w/w) and linearol [by liquid chromatography-tandem mass spectrometry (LC-MS/MS)] were determined from the species. Moreover, vanillin (21 mg, 0.10%, w/w), which was not isolated from any Sideritis species earlier, was isolated from an acetone extract of S. hololeuca. Quantitative amounts of some phenolic compounds in n-hexane, dichloromethane, acetone, methanol extracts and infusion and decoction of the plants were also investigated by LC-MS/MS. Antioxidant capacity and acetylcholinesterase, butyrylcholinesterase inhibition effects of the species were evaluated. The extracts of methanol and infusion and decoction of species showed moderate butyrylcholinesterase inhibition activity. The highest inhibition was observed from the decoction of species. The Cu2+ reducing power of infusion was determined as 1.435 mmol TR g−1.

Kinetics and Mechanisms of Acetylcholinesterase and Butyrylcholinesterase Inhibition by Cardiovascular Drugs and Benzodiazepines

2005 ◽  
Vol 52 (4) ◽  
pp. 843-848 ◽  
Author(s):  
Shyh-Ying Chiou ◽  
Gin-Win Lai ◽  
Yi-Hon Tsai ◽  
Yu-Ru Lee ◽  
Long-Yau Lin ◽  
...  
Keyword(s):  
Cardiovascular Drugs ◽  
Butyrylcholinesterase Inhibition

Butyrylcholinesterase inhibition by miracil D and other compounds

1986 ◽  
Vol 35 (9) ◽  
pp. 1605-1608 ◽  
Author(s):  
Jeff S. Verdier ◽  
Alan David Wolfe
Keyword(s):  
Butyrylcholinesterase Inhibition

Antioxidation activity of oil extracts prepared from various seeds

2012 ◽  
Vol 21 (3) ◽  
pp. 637-643 ◽  
Author(s):  
Jin-Won Lee ◽  
Young-Teck Kim ◽  
Jang-Woo Park ◽  
Chul Rhee
Keyword(s):  
Antioxidation Activity

scholarly journals Phytochemical profile and antioxidation activity of annona fruit and its effect on lymphoma cell proliferation

2019 ◽  
Vol 8 (1) ◽  
pp. 58-68
Author(s):  
Huda Mohammed Al‐Shaya ◽  
Haiwen Li ◽  
Obaid U. Beg ◽  
Anwar A. Hamama ◽  
Sarah Melissa Witiak ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Lymphoma Cell ◽  
Antioxidation Activity ◽  
Phytochemical Profile

scholarly journals Alkaloids from Chlidanthus fragrans and their Acetylcholinesterase, Butyrylcholinesterase and Prolyl Oligopeptidase Activities

2013 ◽  
Vol 8 (11) ◽  
pp. 1934578X1300801 ◽  
Author(s):  
Lucie Cahlíková ◽  
Martina Hrabinová ◽  
Andrea Kulhánková ◽  
Nina Benešová ◽  
Jakub Chlebek ◽  
...  
Keyword(s):  
Nmr Assignments ◽  
2D Nmr ◽  
Inhibition Activity ◽  
Prolyl Oligopeptidase ◽  
Biological Assays ◽  
Amaryllidaceae Alkaloids ◽  
Chemical Structures ◽  
Ellman’S Method ◽  
Butyrylcholinesterase Inhibition

Eleven Amaryllidaceae alkaloids (1–11) were isolated from fresh bulbs of Chlidanthus fragrans Herb. The chemical structures were elucidated by MS, and 1D and 2D NMR spectroscopic experiments. Complete NMR assignments were achieved for deoxypretazzetine (1). All compounds were evaluated for their erythrocytic acetylcholinesterase and serum butyrylcholinesterase inhibition activity using Ellman's method. In the prolyl oligopeptidase assay, Z-Gly-Pro- p-nitroanilide was used as substrate. In biological assays, only the crinine type Amaryllidaceae alkaloid undulatine showed promising acetylcholinesterase and prolyl oligopeptidase inhibition activity with IC50 values of 23.0 ± 1.0 μM and 1.96 ± 0.12 mM, respectively. Other isolated compounds were considered inactive.

Improving the color stability and antioxidation activity of blueberry anthocyanins by enzymatic acylation with p-coumaric acid and caffeic acid

LWT ◽  
2020 ◽  
Vol 130 ◽  
pp. 109673 ◽  
Author(s):  
Jingna Liu ◽  
Yuanhong Zhuang ◽  
Yonghua Hu ◽  
Shan Xue ◽  
Hui Li ◽  
...  
Keyword(s):  
Caffeic Acid ◽  
Color Stability ◽  
Coumaric Acid ◽  
Antioxidation Activity ◽  
Enzymatic Acylation

scholarly journals Responses of the maize plant to chromium stress with reference to antioxidation activity

2012 ◽  
Vol 24 (3) ◽  
pp. 203-212 ◽  
Author(s):  
Saborni Maiti ◽  
Nirmalia Ghosh ◽  
Chiranjib Mandal ◽  
Kingsuk Das ◽  
Narottam Dey ◽  
...  
Keyword(s):  
Maize Plant ◽  
Antioxidation Activity ◽  
Chromium Stress
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