Development of Continuous Filtration in a Novel Continuous Filtration Carousel Integrated with Continuous Crystallization

2019 ◽  
Vol 23 (12) ◽  
pp. 2655-2665 ◽  
Author(s):  
Yiqing C. Liu ◽  
András Domokos ◽  
Simon Coleman ◽  
Paul Firth ◽  
Zoltan K. Nagy
Keyword(s):  
Continuous Crystallization ◽  
Continuous Filtration

scholarly journals Performance of rapid-grown KDP crystals with continuous filtration

2015 ◽  
Vol 3 ◽  
Author(s):  
Guohang Hu ◽  
Yueliang Wang ◽  
Junxiu Chang ◽  
Xiaoyi Xie ◽  
Yuanan Zhao ◽  
...  
Keyword(s):  
Near Infrared ◽  
Laser Damage ◽  
Damage Resistance ◽  
Damage Initiation ◽  
Micron Size ◽  
Continuous Filtration ◽  
Laser Induced Damage ◽  
Almost All ◽  
Lower Correlation ◽  
Kdp Crystals

Rapid growth processing of KDP crystals was improved by employing continuous filtration to eliminate bulk defects. The performances of the KDP crystals, including scattering defects, laser damage resistance and transmittance, were measured and analyzed. Compared with rapid-grown KDP without continuous filtration, the transmittance in the near-infrared was increased by at least 2%, almost all of ‘micron size’ defects were eliminated and ‘sub-micron size’ defects were decreased by approximately 90%. Laser damage testing revealed that the laser-induced damage thresholds (LIDTs), as well as the consistency of the LIDTs from sample to sample, were improved greatly. Moreover, it identified that ‘micron size’ defects were the precursors which initiated laser damage at relative lower laser fluence (4–6 J cm−2), and there was a lower correlation between smaller size scattering defects and laser damage initiation. The improved consistency in the LIDTs, attributed to elimination of ‘micron size’ defects, and LIDT enhancement originated from the decreased absorption of the KDP crystals.

scholarly journals Nucleation in continuous flow cooling sonocrystallization for coiled capillary crystallizers

2021 ◽  
Author(s):  
Mira Schmalenberg ◽  
Lena K. Weick ◽  
Norbert Kockmann
Keyword(s):  
Time Distribution ◽  
Residence Time Distribution ◽  
Flow Cell ◽  
Deionized Water ◽  
Small Scale ◽  
Non Invasive ◽  
Ultrasonic Bath ◽  
Continuous Crystallization ◽  
Wide Range ◽  
Inner Diameter

AbstractNucleation in continuously operated capillary coiled cooling crystallizers is experimentally investigated under the influence of ultrasound. It was found that there is no sharp boundary but rather a transition zone for nucleation under sonication. For this purpose, a tube with an inner diameter of 1.6 mm and a length of 6 m was winded in a coiled flow inverter (CFI) design and immersed into a cooled ultrasonic bath (37 kHz). The CFI design was chosen for improved radial mixing and narrow residence time distribution, which is also investigated. Amino acid l-alanine dissolved in deionized water is employed in a supersaturation range of 1.10 to 1.46 under quiet and sonicated conditions. Nucleation is non-invasive detected using a flow cell equipped with a microscope and camera. Graphical abstract Since the interest and demand for small-scale, continuous crystallization increases, seed crystals were generated in a coiled tube via sonication and optically investigated and characterized. No distinct threshold for nucleation could be determined in a wide range of supersaturations of l-alanine in water

Fouling in a Micro Heat Exchanger During Continuous Crystallization of Solid Lipid Nanoparticles

2014 ◽  
Vol 36 (7-8) ◽  
pp. 731-740 ◽  
Author(s):  
Martin Schoenitz ◽  
Jan Henrik Finke ◽  
Sebastian Melzig ◽  
Annika Hohlen ◽  
Nils Warmeling ◽  
...  
Keyword(s):  
Heat Exchanger ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Solid Lipid ◽  
Continuous Crystallization ◽  
Micro Heat Exchanger
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