Self-Assembled Blends of AB/BAB Block Copolymers Prepared through Dispersion RAFT Polymerization

2016 ◽  
Vol 49 (12) ◽  
pp. 4490-4500 ◽  
Author(s):  
Chengqiang Gao ◽  
Jiaping Wu ◽  
Heng Zhou ◽  
Yaqing Qu ◽  
Baohui Li ◽  
...  
Keyword(s):  
Block Copolymers ◽  
Raft Polymerization ◽  
Self Assembled

scholarly journals Gold-Loaded Organic/Inorganic Nanocomposite Honeycomb Membranes

2006 ◽  
Vol 59 (8) ◽  
pp. 539 ◽  
Author(s):  
Kok Hou Wong ◽  
Thomas P. Davis ◽  
Christopher Barner-Kowollik ◽  
Martina H. Stenzel
Keyword(s):  
Block Copolymer ◽  
Block Copolymers ◽  
Raft Polymerization ◽  
Porous Films ◽  
Breath Figures ◽  
Vinyl Pyridine ◽  
Self Assembled ◽  
Gold Nanocomposites ◽  
Hydrolysis Of ◽  
Porous Array

RAFT polymerization was used to prepare polystyrene – poly(4-vinyl pyridine) block copolymers, PSn-b-P(4VP)m. Well-defined block copolymers were obtained despite some indications of hydrolysis of the RAFT endgroup during synthesis. The block copolymer PS70-b-P(4VP)55 was self-assembled into micellar structures in dichloromethane, leading to nanoparticles with hydrodynamic diameters of 70 nm. The micelles were loaded with HAuCl4 and, upon reduction, micellar gold-containing nanoparticles with hydrodynamic diameters of 240 nm were obtained. These nanoparticles were employed in the preparation of honeycomb-structured porous films by means of the breath figures technique to yield gold nanocomposites with a hexagonal porous array.

Amphiphilic functional block copolymers bearing a reactive furfuryl group via RAFT polymerization; reversible core cross-linked micelles via a Diels–Alder “click reaction”

RSC Advances ◽  
2016 ◽  
Vol 6 (3) ◽  
pp. 2455-2463 ◽  
Author(s):  
Nabendu B. Pramanik ◽  
Nikhil K. Singha
Keyword(s):  
Block Copolymers ◽  
Aqueous Medium ◽  
Click Reaction ◽  
Raft Polymerization ◽  
Diels Alder ◽  
Functional Block ◽  
Self Assembled ◽  
Functional Block Copolymers

Amphiphilic BCPs, PFMA-b-PPEGMA were prepared via RAFT polymerization. They were self-assembled into micelles in aqueous medium with a hydrophobic PFMA core and hydrophilic PPEGMA corona. Core cross-linked micelles were prepared via the DA reaction.

Hierarchically Ordered Microstructures Self-Assembled from Comb−Coil Block Copolymers

Langmuir ◽  
2009 ◽  
Vol 25 (8) ◽  
pp. 4735-4742 ◽  
Author(s):  
Liquan Wang ◽  
Jiaping Lin ◽  
Liangshun Zhang
Keyword(s):  
Block Copolymers ◽  
Self Assembled ◽  
Ordered Microstructures

One-step synthesis of poly(2-oxazoline)-based amphiphilic block copolymers using a dual initiator for RAFT polymerization and CROP

Polymer ◽  
2014 ◽  
Vol 55 (23) ◽  
pp. 5986-5990 ◽  
Author(s):  
Young Chang Yu ◽  
Hang Sung Cho ◽  
Woong-Ryeol Yu ◽  
Ji Ho Youk
Keyword(s):  
Block Copolymers ◽  
Raft Polymerization ◽  
Amphiphilic Block Copolymers ◽  
One Step

Solvent Effects on the Synthesis of Polymeric Nanoparticles via Block Copolymer Self-Assembly Using Microporous Membranes

2020 ◽  
Vol 1000 ◽  
pp. 324-330
Author(s):  
Sri Agustina ◽  
Masayoshi Tokuda ◽  
Hideto Minami ◽  
Cyrille Boyer ◽  
Per B. Zetterlund
Keyword(s):  
Block Copolymer ◽  
Block Copolymers ◽  
Self Assembly ◽  
Polymeric Nanoparticles ◽  
Raft Polymerization ◽  
Membrane Emulsification ◽  
Membrane Pore ◽  
Novel Technique ◽  
Wide Range ◽  
Membrane Pore Size

The self-assembly of block copolymers has attracted attention for many decades because it can yield polymeric nanoobjects with a wide range of morphologies. Membrane emulsification is a fairly novel technique for preparation of various types of emulsions, which relies on the dispersed phase passing through a membrane in order to effect droplet formation. In this study, we have prepared polymeric nanoparticles of different morphologies using self-assembly of asymmetric block copolymers in connection with membrane emulsification. Shirasu Porous Glass (SPG) membranes has been employed as the membrane emulsification equipment, and poly (oligoethylene glycol acrylate)-block-poly (styrene) (POEGA-b-PSt) copolymers prepared via RAFT polymerization. It has been found that a number of different morphologies can be achieved using this novel technique, including spheres, rods, and vesicles. Interestingly, the results have shown that the morphology can be controlled not only by adjusting experimental parameters specific to the membrane emulsification step such as membrane pore size and pressure, but also by changing the nature of organic solvent. As such, this method provides a novel route to these interesting nanoobjects, with interesting prospects in terms of exercising morphology control without altering the nature of the block copolymer itself.

scholarly journals Overcoming Biological Barriers With Block Copolymers-Based Self-Assembled Nanocarriers. Recent Advances in Delivery of Anticancer Therapeutics

2020 ◽  
Vol 11 ◽  
Author(s):  
Jazmin Torres ◽  
Namdev Dhas ◽  
Marcela Longhi ◽  
Mónica C. García
Keyword(s):  
Block Copolymers ◽  
Cancer Treatment ◽  
Common Life ◽  
Biological Barriers ◽  
Life Threatening Illness ◽  
Ability To Act ◽  
Anticancer Therapeutics ◽  
Life Threatening ◽  
Self Assembled ◽  
Treatment And Diagnosis

Cancer is one of the most common life-threatening illness and it is the world’s second largest cause of death. Chemotherapeutic anticancer drugs have many disadvantages, which led to the need to develop novel strategies to overcome these shortcomings. Moreover, tumors are heterogenous in nature and there are various biological barriers that assist in treatment reisistance. In this sense, nanotechnology has provided new strategies for delivery of anticancer therapeutics. Recently, delivery platforms for overcoming biological barriers raised by tumor cells and tumor-bearing hosts have been reported. Among them, amphiphilic block copolymers (ABC)-based self-assembled nanocarriers have attracted researchers worldwide owing to their unique properties. In this work, we addressed different biological barriers for effective cancer treatment along with several strategies to overcome them by using ABC‐based self-assembled nanostructures, with special emphasis in those that have the ability to act as responsive nanocarriers to internal or external environmental clues to trigger release of the payload. These nanocarriers have shown promising properties to revolutionize cancer treatment and diagnosis, but there are still challenges for their successful translation to clinical applications.

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