Mechanical Properties with Respect to Water Content of Host–Guest Hydrogels

2021 ◽  
Vol 54 (17) ◽  
pp. 8067-8076 ◽  
Author(s):  
Motofumi Osaki ◽  
Shin Yonei ◽  
Chiharu Ueda ◽  
Ryohei Ikura ◽  
Junsu Park ◽  
...  
2018 ◽  
Vol 24 (8) ◽  
pp. 843-854 ◽  
Author(s):  
Weiguo Xu ◽  
Shujun Dong ◽  
Yuping Han ◽  
Shuqiang Li ◽  
Yang Liu

Hydrogels, as a class of materials for tissue engineering and drug delivery, have high water content and solid-like mechanical properties. Currently, hydrogels with an antibacterial function are a research hotspot in biomedical field. Many advanced antibacterial hydrogels have been developed, each possessing unique qualities, namely high water swellability, high oxygen permeability, improved biocompatibility, ease of loading and releasing drugs and structural diversity. In this article, an overview is provided on the preparation and applications of various antibacterial hydrogels. Furthermore, the prospects in biomedical researches and clinical applications are predicted.


2021 ◽  
pp. 105678952199119
Author(s):  
Kai Yang ◽  
Qixiang Yan ◽  
Chuan Zhang ◽  
Wang Wu ◽  
Fei Wan

To explore the mechanical properties and damage evolution characteristics of carbonaceous shale with different confining pressures and water-bearing conditions, triaxial compression tests accompanied by simultaneous acoustic emission (AE) monitoring were conducted on carbonaceous shale rock specimens. The AE characteristics of carbonaceous shale were investigated, a damage assessment method based on Shannon entropy of AE was further proposed. The results suggest that the mechanical properties of carbonaceous shale intensify with increasing confining pressure and degrade with increasing water content. Moisture in rocks does not only weaken the cohesion but also reduce the internal friction angle of carbonaceous shale. It is observed that AE activities mainly occur in the post-peak stage and the strong AE activities of saturated carbonaceous shale specimens appear at a lower normalized stress level than that of natural-state specimens. The maximum AE counts and AE energy increase with water content while decrease with confining pressure. Both confining pressure and water content induce changes in the proportions of AE dominant frequency bands, but the changes caused by confining pressure are more significant than those caused by water content. The results also indicate that AE entropy can serve as an applicable index for rock damage assessment. The damage evolution process of carbonaceous shale can be divided into two main stages, including the stable damage development stage and the damage acceleration stage. The damage variable increases slowly accompanied by a few AE activities at the first stage, which is followed by a rapid growth along with intense acoustic emission activities at the damage acceleration stage. Moreover, there is a sharp rise in the damage evolution curve for the natural-state specimen at the damage acceleration stage, while the damage variable develops slowly for the saturated-state specimen.


2015 ◽  
Vol 51 (4) ◽  
pp. 901-909 ◽  
Author(s):  
Kassandra Azevedo Tadini ◽  
Daiane Garcia Mercurio ◽  
Patrícia Maria Berardo Gonçalves Maia Campos

abstract Acetyl hexapeptide-3 has been used in anti-aging topical formulations aimed at improving skin appearance. However, few basic studies address its effects on epidermis and dermis, when vehiculated in topical formulations. Thus, the objective of this study was to determine the clinical efficacy of acetyl hexapeptide-3 using biophysical techniques. For this purpose, formulations with and without acetyl hexapeptide-3 were applied to the ventral forearm and the face area of forty female volunteers. Skin conditions were evaluated after 2 and 4-week long daily applications, by analyzing the stratum corneum water content and the skin mechanical properties, using three instruments, the Corneometer(r) CM 825, CutometerSEM 575 and ReviscometerRV600. All formulations tested increased the stratum corneum water content in the face region, which remained constant until the end of the study. In contrast, only formulations containing acetyl hexapeptide-3 exhibit a significant effect on mechanical properties, by decreasing the anisotropy of the face skin. No significant effects were observed in viscoelasticity parameters. In conclusion, the effects of acetyl hexapeptide-3 on the anisotropy of face skin characterize the compound as an effective ingredient for improving conditions of the cutaneous tissue, when used in anti-aging cosmetic formulations.


2016 ◽  
Vol 17 (3) ◽  
pp. 1057-1066 ◽  
Author(s):  
Kenjiro Yazawa ◽  
Kana Ishida ◽  
Hiroyasu Masunaga ◽  
Takaaki Hikima ◽  
Keiji Numata

1966 ◽  
Vol 44 (1) ◽  
pp. 59-68
Author(s):  
S. H. P. MADDRELL

1. When larvae of Rhodnius feed, the abdominal wall rapidly becomes extensible. This change is brought about peripherally by the abdominal nervous supply; as a consequence, abdominal segments which have been denervated fail to stretch as much at feeding as do neighbouring innervated segments. 2. The stimulus for this change originates in the head. It appears that the sensations accompanying feeding are responsible and that they have a cumulative effect, so that the degree of plasticization of the abdominal wall depends on the length of time during which the insect has been sucking. 3. Neurosecretory axons are the only known efferent supply to the abdominal wall and so it is most probable that they cause the localized plasticization. 4. The evidence suggests that the plasticization of the abdominal cuticle is a result of an increase in its water content. 5. The increase in plasticity of the abdominal wall is temporary, the effect decreasing progressively after feeding.


2019 ◽  
Vol 292 ◽  
pp. 102-107 ◽  
Author(s):  
Josef Fládr ◽  
Petr Bílý ◽  
Karel Šeps ◽  
Roman Chylík ◽  
Vladimír Hrbek

High-performance concrete is a very specific type of concrete. Its production is sensitive to both the quality of compounds used and the order of addition of particular compounds during the homogenization process. The mechanical properties were observed for four dosing procedures of each of the three tested concrete mixtures. The four dosing procedures were identical for the three mixes. The three mixes varied only in the type of supplementary cementitious material used and in water content. The water content difference was caused by variable k-value of particular additives. The water-to-binder ratio was kept constant for all the concretes. The additives used were metakaolin, fly ash and microsilica. The comparison of particular dosing procedures was carried out on the values of basic mechanical properties of concrete. The paper compares compressive strength and depth of penetration of water under pressure. Besides the comparsion of macro-mechanical properties, the effect of microsilica and fly ash additives on micro-mechanical properties was observed with the use of scanning electron microscopy (SEM) and nanoindentation data analysis. Nanoindentation was used to determine the thickness and strength of interfacial transition zone (ITZ) for different sequence of addition of cement, additive and aggregate. The thickness obtained by nanoindentation was further investigated by SEM EDS line scanning.


2018 ◽  
Vol 175 ◽  
pp. 01003
Author(s):  
Bingquan Sun ◽  
Jiajia Sun

This paper, from the point of view of improving compactness of density and crystal water content of radiation-proof concrete, using magnesite with high crystal water content as aggregate and alkaline potential water as mixing water, prepared ordinary density radiation-proof concrete and studied its mechanical properties, resistivity and pore structure. The results show that, compared to base ordinary concrete, the prepared concrete has better 28d compressive strength and resistivity, overall porosity decreases by 17%, and pore gradation at all ages improves significantly. It is indicated that the prepared magnesite aggregate radiation concrete has good density and durability, improves concrete radiation protection performance.


2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Jik Hang Clifford Lee ◽  
Benjamin Ondruschka ◽  
Lisa Falland-Cheung ◽  
Mario Scholze ◽  
Niels Hammer ◽  
...  

With increasingly detailed imaging and mechanical analysis, modalities need arises to update methodology and assessment criteria for skull bone analysis to understand how bone microarchitecture and the presence of attached tissues may affect the response to mechanical load. The main aim was to analyze the effect of macroscopic and microstructural features, as well as periosteal attachment, on the mechanical properties of human skull bone. Fifty-six skull specimens from ethanol-phenoxyethanol-embalmed cadavers were prepared from two human cadavers. Assuming symmetry of the skull, all samples from one-half each were stripped of periosteum and dura mater, while the soft tissues were kept intact on the remaining samples on the contralateral side. The specimens were analyzed using microcomputed tomography to assess trabecular connectivity density, total surface area, and volume ratio. The specimens were loaded under three-point bend tests until fracture with optical co-registration. The bone fragments were then lyophilized to measure their water content. With increasingly detailed imaging and mechanical analysis modalities, there is a need to update methodology and assessment criteria for skull bone analysis to understand how the bone microarchitecture and the presence of attached tissues may affect the response to mechanical load. The mechanical properties were negatively correlated to bone thickness and water content. Conversely, most microarchitectural features did not influence either mechanical parameter. The correlation between mechanical response data and morphologic properties remains similar between the results of embalmed tissues presented here and fresh osseous tissue from literature data. The findings presented here add to the existing methodology to assess human skull for research purposes. The interaction between most microarchitectural features in ethanol-phenoxyethanol-embalmed embalmed skull samples and bending stress appear to be minute.


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