Polyunsaturated Fatty Acid Diet and Upregulation of Lipoxin A4 Reduce the Inflammatory Response of Preeclampsia

2020 ◽  
Vol 20 (1) ◽  
pp. 357-368
Author(s):  
Minghui Ou ◽  
Qian Zhang ◽  
Huidong Zhao ◽  
Chang Shu
Keyword(s):  
Fatty Acid ◽  
Inflammatory Response ◽  
Polyunsaturated Fatty Acid ◽  
Lipoxin A4 ◽  
Acid Diet

A high n-6 polyunsaturated fatty acid diet reduces muscarinic M2/M4 receptor binding in the rat brain

2005 ◽  
Vol 29 (4) ◽  
pp. 282-288 ◽  
Author(s):  
Teresa Marie du Bois ◽  
Warren Bell ◽  
Chao Deng ◽  
Xu-Feng Huang
Keyword(s):  
Fatty Acid ◽  
Rat Brain ◽  
Polyunsaturated Fatty Acid ◽  
Receptor Binding ◽  
Acid Diet

Syndrome in Premature Infants Associated with Low Plasma Vitamin E Levels and High Polyunsaturated Fatty Acid Diet

1966 ◽  
Vol 19 (3) ◽  
pp. 147-157 ◽  
Author(s):  
HABIBA HASSAN ◽  
SAMI A. HASHIM ◽  
THEODORE B. VAN ITALLIE ◽  
WILLIAM H. SEBRELL
Keyword(s):  
Fatty Acid ◽  
Vitamin E ◽  
Polyunsaturated Fatty Acid ◽  
Premature Infants ◽  
Plasma Vitamin ◽  
Acid Diet ◽  
Plasma Vitamin E

scholarly journals Diet Supplementation in ω3 Polyunsaturated Fatty Acid Favors an Anti-Inflammatory Basal Environment in Mouse Adipose Tissue

Nutrients ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 438 ◽  
Author(s):  
Cecilia Colson ◽  
Rayane Ghandour ◽  
Océane Dufies ◽  
Samah Rekima ◽  
Agnès Loubat ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Adipose Tissue ◽  
Fatty Acid ◽  
Inflammatory Response ◽  
Polyunsaturated Fatty Acids ◽  
Polyunsaturated Fatty Acid ◽  
Inflammatory Cytokine ◽  
M2 Macrophage ◽  
Anti Inflammatory ◽  
Diet Supplementation

Oxylipins are metabolized from dietary ω3 and ω6 polyunsaturated fatty acids and are involved in an inflammatory response. Adipose tissue inflammatory background is a key factor of metabolic disorders and it is accepted that dietary fatty acids, in terms of quality and quantity, modulate oxylipin synthesis in this tissue. Moreover, it has been reported that diet supplementation in ω3 polyunsaturated fatty acids resolves some inflammatory situations. Thus, it is crucial to assess the influence of dietary polyunsaturated fatty acids on oxylipin synthesis and their impact on adipose tissue inflammation. To this end, mice fed an ω6- or ω3-enriched standard diet (ω6/ω3 ratio of 30 and 3.75, respectively) were analyzed for inflammatory phenotype and adipose tissue oxylipin content. Diet enrichment with an ω3 polyunsaturated fatty acid induced an increase in the oxylipins derived from ω6 linoleic acid, ω3 eicosapentaenoic, and ω3 docosahexaenoic acids in brown and white adipose tissues. Among these, the level of pro-resolving mediator intermediates, as well as anti-inflammatory metabolites, were augmented. Concomitantly, expressions of M2 macrophage markers were increased without affecting inflammatory cytokine contents. In vitro, these metabolites did not activate macrophages but participated in macrophage polarization by inflammatory stimuli. In conclusion, we demonstrated that an ω3-enriched diet, in non-obesogenic non-inflammatory conditions, induced synthesis of oxylipins which were involved in an anti-inflammatory response as well as enhancement of the M2 macrophage molecular signature, without affecting inflammatory cytokine secretion.

Treatment of the enhanced intestinal uptake of glucose in diabetic rats with a polyunsaturated fatty acid diet

1987 ◽  
Vol 905 (2) ◽  
pp. 426-434 ◽  
Author(s):  
A.B.R. Thomson ◽  
M. Keelan ◽  
M.T. Clandinin ◽  
R.V. Rajotte ◽  
C.I. Cheeseman ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Diabetic Rats ◽  
Intestinal Uptake ◽  
Acid Diet

TREATMENT OF IDIOPATHIC POLYNEURITIS BY A POLYUNSATURATED FATTY-ACID DIET

The Lancet ◽  
1978 ◽  
Vol 311 (8064) ◽  
pp. 583-585 ◽  
Author(s):  
B.D. Bower ◽  
E.A. Newsholme
Keyword(s):  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Acid Diet

A High-Cholesterol, n–3 Polyunsaturated Fatty Acid Diet Causes Different Responses in Rats and Hamsters

2005 ◽  
Vol 49 (6) ◽  
pp. 386-391 ◽  
Author(s):  
Mei-Huei Lin ◽  
Shao-Chun Lu ◽  
Po-Chao Huang ◽  
Young-Chau Liu ◽  
Shyun-Yeu Liu
Keyword(s):  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
High Cholesterol ◽  
Acid Diet

scholarly journals Mechanisms Mediating the Effects of Prepubertal (n-3) Polyunsaturated Fatty Acid Diet on Breast Cancer Risk in Rats

2005 ◽  
Vol 135 (12) ◽  
pp. 2946S-2952S ◽  
Author(s):  
Leena Hilakivi-Clarke ◽  
Susan E. Olivo ◽  
Ayesha Shajahan ◽  
Galam Khan ◽  
Yuelin Zhu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Fatty Acid ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Polyunsaturated Fatty Acid ◽  
Acid Diet
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