Simultaneous Imaging and Selective Photothermal Therapy through Aptamer-Driven Au Nanosphere Clustering

2018 ◽  
Vol 10 (2) ◽  
pp. 183-188 ◽  
Author(s):  
Zhenping Guan ◽  
Taishi Zhang ◽  
Hai Zhu ◽  
Da Lyu ◽  
Sreelatha Sarangapani ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Simultaneous Imaging ◽  
Au Nanosphere

Facile one-pot synthesis of carbon/calcium phosphate/Fe3O4 composite nanoparticles for simultaneous imaging and pH/NIR-responsive drug delivery

2016 ◽  
Vol 52 (74) ◽  
pp. 11068-11071 ◽  
Author(s):  
Mingyu Gou ◽  
Shengnan Li ◽  
Lingyu Zhang ◽  
Lu Li ◽  
Chungang Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Calcium Phosphate ◽  
Photothermal Therapy ◽  
Composite Nanoparticles ◽  
One Pot ◽  
Drug Delivery Vehicles ◽  
Simultaneous Imaging ◽  
One Pot Synthesis ◽  
Delivery Vehicles

We report herein a facile one-pot synthesis of carbon/calcium phosphate/Fe3O4 composite nanoparticles, which were employed as pH/NIR-responsive drug delivery vehicles for simultaneous MRI and chemo-photothermal therapy.

A designed synthesis of multifunctional Fe3O4@carbon/zinc phosphate nanoparticles for simultaneous imaging and synergic chemo-photothermal cancer therapy

2016 ◽  
Vol 4 (35) ◽  
pp. 5809-5813 ◽  
Author(s):  
Chunyan Wang ◽  
Lingyu Zhang ◽  
Shengnan Li ◽  
Manjie Zhang ◽  
Tingting Wang ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Photothermal Therapy ◽  
Zinc Phosphate ◽  
Simple Method ◽  
Simultaneous Imaging ◽  
Designed Synthesis

A simple method is developed to synthesize Fe3O4@C/ZnP NPs for simultaneous MRI and synergic chemo-photothermal therapy.

Magnetic iron oxide–fluorescent carbon dots integrated nanoparticles for dual-modal imaging, near-infrared light-responsive drug carrier and photothermal therapy

2014 ◽  
Vol 2 (6) ◽  
pp. 915-923 ◽  
Author(s):  
Hui Wang ◽  
Jing Shen ◽  
Yingyu Li ◽  
Zengyan Wei ◽  
Guixin Cao ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Near Infrared ◽  
Drug Carrier ◽  
Hybrid Nanoparticles ◽  
Infrared Light ◽  
Great Promise ◽  
High Efficacy ◽  
Imaging Diagnostics ◽  
Simultaneous Imaging ◽  
Fluorescent Carbon Dots

The multifunctional hybrid nanoparticles described demonstrate great promise towards advanced nanoplatforms for simultaneous imaging diagnostics and high efficacy therapy.

Nanotheranostics for Cancer Therapy and Detection: State of the Art

2020 ◽  
Vol 26 (42) ◽  
pp. 5503-5517
Author(s):  
Shivani Rai Paliwal ◽  
Rameshroo Kenwat ◽  
Sabyasachi Maiti ◽  
Rishi Paliwal
Keyword(s):  
Carbon Nanotubes ◽  
Gold Nanoparticles ◽  
Cancer Therapy ◽  
Photothermal Therapy ◽  
State Of The Art ◽  
Cellular Level ◽  
Inorganic Materials ◽  
Simultaneous Imaging ◽  
Specific Targeting ◽  
Organ Tissue

Nanotheranostics, an approach of combining both diagnosis and therapy, is one of the latest advances in cancer therapy particularly. Nanocarriers designed and derived from inorganic materials such as like gold nanoparticles, silica nanoparticles, magnetic nanoparticles and carbon nanotubes have been explored for tremendous applications in this area. Similarly, nanoparticles composed of some organic material alone or in combination with inorganic nano-cargos have been developed pre-clinically and possess excellent features desired. Photothermal therapy, MRI, simultaneous imaging and delivery, and combination chemotherapy with a diagnosis are a few of the known methods exploring cancer therapy and detection at organ/tissue/molecular/sub-cellular level. This review comprises an overview of the recent reports meant for nano theranostics purposes. Targeted cancer nanotheranostics have been included for understating tumor micro-environment or cell-specific targeting approach employed. A brief account of various strategies is also included for the readers highlighting the mechanism of cancer therapy.

NIR-active Nanoterminator with Mature Dendritic Cell Acitivities for Immuno-Priming Mild Photothermal Cancer Therapy

2020 ◽  
Author(s):  
zhihong sun ◽  
Guanjun Deng ◽  
Xinghua Peng ◽  
Xiuli Xu ◽  
Lanlan Liu ◽  
...  
Keyword(s):  
Dendritic Cell ◽  
Photothermal Therapy ◽  
Whole Body ◽  
Mature Dendritic Cell ◽  
Immune Microenvironment ◽  
Highly Efficient ◽  
Tumor Immune Microenvironment ◽  
Shock Proteins ◽  
Mild Temperature ◽  
Broad Interest

Recently, photothermal-immuno synergistic therapy under mild temperature (~ 45 °C) has got broad interest in cancer treatment. Inhibition the intratumorally HSPs production is the key to accomplish highly efficient and mild photothermal therapy. In this work, we developed biomimetic nanoterminators with mature DCs functions by coating the mature dendritic cell membrane on photothermal nanoagents. As-prepared nanoterminators could automatically locate on T cell in the complex tumor-immune microenvironment and promote the T cells proliferation, activation and cytokine secretion, which could not only inhibit the expression of heat shock proteins to cooperate on highly efficient mild photothermal therapy (~42°C), but also promote tumor apoptosis during the treatment. More importantly, this nanoterminator could serve as vaccine to trigger anti-tumor immune response of the whole body, which would be promising to long-life tumor inhibition and termination.

Selectively Sensitizing Malignant Cells to Photothermal Therapy Using a CD44-Targeting Heat Shock Protein 72 Depletion Nanosystem

ACS Nano ◽  
2016 ◽  
Vol 10 (9) ◽  
pp. 8578-8590 ◽  
Author(s):  
Shouju Wang ◽  
Ying Tian ◽  
Wei Tian ◽  
Jing Sun ◽  
Shuang Zhao ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Photothermal Therapy ◽  
Malignant Cells ◽  
Heat Shock Protein 72 ◽  
Cd44 Targeting

Human Induced Pluripotent Stem Cells for Tumor Targeted Delivery of Gold Nanorods and Enhanced Photothermal Therapy

ACS Nano ◽  
2016 ◽  
Vol 10 (2) ◽  
pp. 2375-2385 ◽  
Author(s):  
Yanlei Liu ◽  
Meng Yang ◽  
Jingpu Zhang ◽  
Xiao Zhi ◽  
Chao Li ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Gold Nanorods ◽  
Pluripotent Stem Cells ◽  
Targeted Delivery ◽  
Photothermal Therapy ◽  
Induced Pluripotent

Bi19S27I3 nanorods: a new candidate for photothermal therapy in the first and second biological near-infrared windows

Nanoscale ◽  
2021 ◽  
Author(s):  
Jinsong Xiong ◽  
Qinghuan Bian ◽  
Shuijin Lei ◽  
Yatian Deng ◽  
Kehan Zhao ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Research Interest ◽  
The Past ◽  
Nir Light ◽  
Considerable Research ◽  
Key Factor

Near-infrared (NIR) light induced photothermal cancer therapy using nanomaterials as photothermal agents has attracted considerable research interest over the past few years. As the key factor in the photothermal therapy...

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