Interactions between Silica-Coated Gold Nanorod Substrates and Hydrophobic Analytes in Colloidal Surface-Enhanced Raman Spectroscopy

2019 ◽  
Vol 123 (40) ◽  
pp. 24685-24697
Author(s):  
Hyunho Kang ◽  
Christy Haynes
Coatings ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 198 ◽  
Author(s):  
Mehmet Yilmaz

The controlled deposition of nanoparticles onto 3-D nanostructured films is still facing challenges due to the uncontrolled aggregation of colloidal nanoparticles. In the context of this study, a simple yet effective approach is demonstrated to decorate the silver nanoparticles (AgNP) onto the 3-D and anisotropic gold nanorod arrays (GNAs) through a bioinspired polydopamine (PDOP) coating to fabricate surface-enhanced Raman spectroscopy (SERS) platforms. Since the Raman reporter molecules (methylene blue, MB, 10 µM) were not adsorbed directly on the surface of the plasmonic material, a remarkable decrease in SERS signals was detected for the PDOP-coated GNAs (GNA@PDOP) platforms. However, after uniform and well-controlled AgNP decoration on the GNA@PDOP (GNA@PDOP@AgNP), huge enhancement was observed in SERS signals from the resultant platform due to the synergistic action which originated from the interaction of GNAs and AgNPs. I also detected that PDOP deposition time (i.e., PDOP film thickness) is the dominant parameter that determines the SERS activity of the final system and 30 min of PDOP deposition time (i.e., 3 nm of PDOP thickness) is the optimum value to obtain the highest SERS signal. To test the reproducibility of GNA@PDOP@AgNP platforms, relative standard deviation (RSD) values for the characteristic peaks of MB were found to be less than 0.17, demonstrating the acceptable reproducibility all over the proposed platform. This report suggests that GNA@PDOP@AgNP system may be used as a robust platform for practical SERS applications.


ACS Photonics ◽  
2016 ◽  
Vol 3 (6) ◽  
pp. 1027-1035 ◽  
Author(s):  
Pilar G. Vianna ◽  
Daniel Grasseschi ◽  
Greice K. B. Costa ◽  
Isabel C. S. Carvalho ◽  
Sergio H. Domingues ◽  
...  

2018 ◽  
Vol 26 (18) ◽  
pp. 22698 ◽  
Author(s):  
Pilar G. Vianna ◽  
Daniel Grasseschi ◽  
Sergio H. Domingues ◽  
Christiano J. S. de Matos

The Analyst ◽  
2021 ◽  
Author(s):  
Najwan Albarghouthi ◽  
Presley MacMillan ◽  
Christa L. Brosseau

Modified gold nanorod arrays are used as SERS substrates for the detection of atrazine.


ACS Nano ◽  
2013 ◽  
Vol 7 (3) ◽  
pp. 2099-2105 ◽  
Author(s):  
Sean T. Sivapalan ◽  
Brent M. DeVetter ◽  
Timothy K. Yang ◽  
Thomas van Dijk ◽  
Matthew V. Schulmerich ◽  
...  

2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.


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