scholarly journals Ambient Pressure Hydrodesulfurization of Refractory Sulfur Compounds in Highly Sensitive μ-Reactor Platform Coupled to a Time-of-Flight Mass Spectrometer

2018 ◽  
Vol 122 (3) ◽  
pp. 1699-1705 ◽  
Author(s):  
Ann-Louise N. Christoffersen ◽  
Anders Bodin ◽  
Christian F. Elkjær ◽  
Jakob E. Sørensen ◽  
Jakob Kibsgaard ◽  
...  
Keyword(s):  
Mass Spectrometer ◽  
Ambient Pressure ◽  
Time Of Flight ◽  
Sulfur Compounds ◽  
Flight Mass Spectrometer ◽  
Highly Sensitive

scholarly journals Matrix-assisted ionisation in vacuum mass spectrometry and imaging on a modified quadrupole-quadrupole-time-of-flight mass spectrometer

2019 ◽  
Author(s):  
Alex Harding ◽  
James Hough ◽  
Charlotte Curtis ◽  
Daniel Kinsman ◽  
Malcolm Clench
Keyword(s):  
Mass Spectrometry ◽  
Mass Spectrometer ◽  
Ambient Pressure ◽  
Time Of Flight ◽  
Ion Source ◽  
Matrix Composition ◽  
Orifice Diameter ◽  
External Energy ◽  
Source Pressure ◽  
Flight Mass Spectrometer

Matrix-Assisted Ionisation in Vacuum (MAIV) is a new ionisation technique which ionises non-volatile compounds producing electrospray ionisation-like spectra. Its simple, matrix-assisted laser desorption/ionisation-like sample preparation allows for rapid analysis, with no requirement for external energy in the form of a laser or high voltage to produce ions. Ionisation occurs when the matrix (often 3-nitrobenzonitrile) is exposed to sub-ambient pressure. Here, the first use of this revolutionary new ionisation technique to image biological samples is reported. A commercial quadrupole-quadrupole-time-of-flight mass spectrometer was modified to incorporate control of the ion source pressure and a reduced sampling cone orifice diameter. In initial experiments, optimisation of source pressure and matrix composition was carried out to increase the longevity of ion formation. It was noted during these experiments that ion production was only observed when the sample was directly under the sampling cone. Optimisation of sample extraction into the MAIV matrix by the addition of 5% chloroform enabled MAIV mass spectrometry imaging of lipids in rat brain sections to be carried out in raster imaging mode. Modification of the size and position of the sampling cone improved the selectivity obtainable in these images. Although the quality of these initial images is relatively poor, work is underway to improve the spatial resolution by further modification of the ion source and progress is reported.

A TIME-OF-FLIGHT MASS SPECTROMETER FOR SIMS AND FIELD IONISED NEUTRAL ANALYSIS USING A PULSED LMIS

1987 ◽  
Vol 48 (C6) ◽  
pp. C6-577-C6-582 ◽  
Author(s):  
A. R. Waugh ◽  
D. R. Kingham ◽  
C. H. Richardson ◽  
M. Goff
Keyword(s):  
Mass Spectrometer ◽  
Time Of Flight ◽  
Flight Mass Spectrometer

Lumas-30 time-of-flight mass spectrometer with pulsed glow discharge for direct determination of nitrogen in steel

2011 ◽  
Vol 66 (14) ◽  
pp. 1411-1416 ◽  
Author(s):  
A. A. Ganeev ◽  
A. R. Gubal’ ◽  
V. I. Mosichev ◽  
N. V. Pershin ◽  
S. N. Petrov ◽  
...  
Keyword(s):  
Glow Discharge ◽  
Mass Spectrometer ◽  
Time Of Flight ◽  
Direct Determination ◽  
Pulsed Glow Discharge ◽  
Flight Mass Spectrometer
Sign in / Sign up

Export Citation Format

Share Document