Dual Role of Missing-Linker Defects Terminated by Acetate Ligands in a Zirconium-Based MOF in Promoting Photocatalytic Hydrogen Peroxide Production

2021 ◽  
Author(s):  
Yoshifumi Kondo ◽  
Yasutaka Kuwahara ◽  
Kohsuke Mori ◽  
Hiromi Yamashita
Keyword(s):  
Hydrogen Peroxide ◽  
Dual Role ◽  
Hydrogen Peroxide Production

scholarly journals Thimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNA

2012 ◽  
Vol 2012 ◽  
pp. 1-12 ◽  
Author(s):  
Martyn A. Sharpe ◽  
Andrew D. Livingston ◽  
David S. Baskin
Keyword(s):  
Hydrogen Peroxide ◽  
Caspase 3 ◽  
Permeability Transition ◽  
Fold Increase ◽  
Hydrogen Peroxide Production ◽  
Fenton Chemistry ◽  
Human Astrocytes ◽  
Mitochondrial Toxin ◽  
Normal Human

Thimerosal generates ethylmercury in aqueous solution and is widely used as preservative. We have investigated the toxicology of Thimerosal in normal human astrocytes, paying particular attention to mitochondrial function and the generation of specific oxidants. We find that ethylmercury not only inhibits mitochondrial respiration leading to a drop in the steady state membrane potential, but also concurrent with these phenomena increases the formation of superoxide, hydrogen peroxide, and Fenton/Haber-Weiss generated hydroxyl radical. These oxidants increase the levels of cellular aldehyde/ketones. Additionally, we find a five-fold increase in the levels of oxidant damaged mitochondrial DNA bases and increases in the levels of mtDNA nicks and blunt-ended breaks. Highly damaged mitochondria are characterized by having very low membrane potentials, increased superoxide/hydrogen peroxide production, and extensively damaged mtDNA and proteins. These mitochondria appear to have undergone a permeability transition, an observation supported by the five-fold increase in Caspase-3 activity observed after Thimerosal treatment.

Dual role of hydrogen peroxide on the oxidase-like activity of nanoceria and its application for colorimetric hydrogen peroxide and glucose sensing

RSC Advances ◽  
2016 ◽  
Vol 6 (65) ◽  
pp. 59939-59945 ◽  
Author(s):  
Ruochen Guo ◽  
Yanru Wang ◽  
Shaoxuan Yu ◽  
Wenxin Zhu ◽  
Fangqing Zheng ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Catalytic Activity ◽  
Cerium Oxide ◽  
Glucose Sensing ◽  
Dual Role ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Chromogenic Substrate

Nanoceria (cerium oxide nanoparticles) exhibits excellent catalytic activity towards chromogenic substrate 3,3,5,5-tetramethylbenzidine (TMB) in the presence of hydrogen peroxide (H2O2), which has been reported.

A mild and chemoselective CALB biocatalysed synthesis of sulfoxides exploiting the dual role of AcOEt as solvent and reagent

2021 ◽  
Vol 19 (1) ◽  
pp. 156-161
Author(s):  
Silvia Anselmi ◽  
Siyu Liu ◽  
Seong-Heun Kim ◽  
Sarah M. Barry ◽  
Thomas S. Moody ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Dual Role ◽  
Mild Conditions ◽  
Urea Hydrogen Peroxide ◽  
Role Of Solvent

Sulfoxides have been synthesised from various sulfide substrates under mild conditions exploiting CALB biocatalyst in the presence of urea hydrogen peroxide and AcOEt which acts with the dual role of solvent and reagent.

The dual role of hydrogen peroxide in fuel cells

2015 ◽  
Vol 60 (1) ◽  
pp. 55-64 ◽  
Author(s):  
Liang An ◽  
Tianshou Zhao ◽  
Xiaohui Yan ◽  
Xuelong Zhou ◽  
Peng Tan
Keyword(s):  
Hydrogen Peroxide ◽  
Fuel Cells ◽  
Dual Role
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