Development of Polythiophene–Tripeptide Covalent Conjugates Showing Excellent Structure-Dependent Photophysical and Photocurrent Properties

2021 ◽  
Author(s):  
Sanjoy Mondal ◽  
Soumyajit Hazra ◽  
Arnab Shit ◽  
Dhruba P. Chatterjee ◽  
Arindam Banerjee ◽  
...  
Keyword(s):  
Covalent Conjugates

Effects of Covalent Conjugates of Fullerene Derivatives with Xanthene Dyes on Activity of Ca2+-ATPase of the Sarcoplasmic Reticulum

2020 ◽  
Vol 169 (1) ◽  
pp. 89-94
Author(s):  
L. V. Tatyanenko ◽  
O. V. Pokidova ◽  
N. S. Goryachev ◽  
O. A. Kraevaya ◽  
E. A. Khakina ◽  
...  
Keyword(s):  
Sarcoplasmic Reticulum ◽  
Xanthene Dyes ◽  
Fullerene Derivatives ◽  
Covalent Conjugates

Cellular uptake of covalent conjugates of oligonucleotide with membrane-modifying peptide, peptaibol

2012 ◽  
Vol 20 (10) ◽  
pp. 3219-3222 ◽  
Author(s):  
Shun-ichi Wada ◽  
Yasunari Hitora ◽  
Saori Yokoe ◽  
Osamu Nakagawa ◽  
Hidehito Urata
Keyword(s):  
Cellular Uptake ◽  
Covalent Conjugates

Structural and thermodynamic features of covalent conjugates of sodium caseinate with maltodextrins underlying their functionality

2012 ◽  
Vol 3 (3) ◽  
pp. 283-289 ◽  
Author(s):  
N. V. Grigorovich ◽  
D. V. Moiseenko ◽  
A. S. Antipova ◽  
M. S. Anokhina ◽  
L. E. Belyakova ◽  
...  
Keyword(s):  
Sodium Caseinate ◽  
Covalent Conjugates

scholarly journals Role of the Lipoperoxidation Product 4-Hydroxynonenal in the Pathogenesis of Severe Malaria Anemia and Malaria Immunodepression

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Evelin Schwarzer ◽  
Paolo Arese ◽  
Oleksii A. Skorokhod
Keyword(s):  
Oxidative Stress ◽  
Severe Malaria ◽  
Chemical Properties ◽  
Oxidative Stress Marker ◽  
Pathogenic Factor ◽  
Biologically Relevant ◽  
Cell Functions ◽  
Low Concentrations ◽  
Covalent Conjugates

Oxidative stress plays an important role in the pathogenesis offalciparummalaria, a disease still claiming close to 1 million deaths and 200 million new cases per year. Most frequent complications are severe anemia, cerebral malaria, and immunodepression, the latter being constantly present in all forms of malaria. Complications are associated with oxidative stress and lipoperoxidation. Its final product 4-hydroxynonenal (4-HNE), a stable yet very reactive and diffusible molecule, forms covalent conjugates with proteins, DNA, and phospholipids and modulates important cell functions at very low concentrations. Since oxidative stress plays important roles in the pathogenesis of severe malaria, it appears important to explore the role of 4-HNE in two important malaria complications such as malaria anemia and malaria immunodepression where oxidative stress is considered to be involved. In this review we will summarize data about 4-HNE chemistry, its biologically relevant chemical properties, and its role as regulator of physiologic processes and as pathogenic factor. We will review studies documenting the role of 4-HNE in severe malaria with emphasis on malaria anemia and immunodepression. Data from other diseases qualify 4-HNE both as oxidative stress marker and as pathomechanistically important molecule. Further studies are needed to establish 4-HNE as accepted pathogenic factor in severe malaria.

A solid-phase method for peptide–siRNA covalent conjugates based on click chemistry

MedChemComm ◽  
2012 ◽  
Vol 3 (4) ◽  
pp. 506 ◽  
Author(s):  
Yang Liu ◽  
Xiao-Feng Wang ◽  
Yue Chen ◽  
Li-He Zhang ◽  
Zhen-Jun Yang
Keyword(s):  
Click Chemistry ◽  
Solid Phase ◽  
Phase Method ◽  
Solid Phase Method ◽  
Covalent Conjugates
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