Role of Surface Functionalization on Cellular Uptake of AuNPs Characterized by Computational Microscopy

2020 ◽  
Vol 124 (10) ◽  
pp. 1898-1908 ◽  
Author(s):  
Thodsaphon Lunnoo ◽  
Jirawat Assawakhajornsak ◽  
Sukhum Ruangchai ◽  
Theerapong Puangmali
Polymers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1026
Author(s):  
Elisa Chiodi ◽  
Allison M. Marn ◽  
Matthew T. Geib ◽  
M. Selim Ünlü

The importance of microarrays in diagnostics and medicine has drastically increased in the last few years. Nevertheless, the efficiency of a microarray-based assay intrinsically depends on the density and functionality of the biorecognition elements immobilized onto each sensor spot. Recently, researchers have put effort into developing new functionalization strategies and technologies which provide efficient immobilization and stability of any sort of molecule. Here, we present an overview of the most widely used methods of surface functionalization of microarray substrates, as well as the most recent advances in the field, and compare their performance in terms of optimal immobilization of the bioreceptor molecules. We focus on label-free microarrays and, in particular, we aim to describe the impact of surface chemistry on two types of microarray-based sensors: microarrays for single particle imaging and for label-free measurements of binding kinetics. Both protein and DNA microarrays are taken into consideration, and the effect of different polymeric coatings on the molecules’ functionalities is critically analyzed.


2013 ◽  
Vol 13 (10) ◽  
pp. 6485-6498 ◽  
Author(s):  
Ningning Ma ◽  
Chao Ma ◽  
Chuanyan Li ◽  
Ting Wang ◽  
Yongjun Tang ◽  
...  

1997 ◽  
Vol 7 (14) ◽  
pp. 1909-1914 ◽  
Author(s):  
Charles J. Stankovic ◽  
Narayanan Surendran ◽  
Elizabeth A. Lunney ◽  
Mark S. Plummer ◽  
Kimberly S. Para ◽  
...  
Keyword(s):  

2016 ◽  
Vol 18 (45) ◽  
pp. 30946-30953 ◽  
Author(s):  
Damien Magne ◽  
Vincent Mauchamp ◽  
Stéphane Célérier ◽  
Patrick Chartier ◽  
Thierry Cabioc'h

The role of the surface groups in chemical bonding in two dimensional Ti3C2is evidenced at the nano-object level.


2018 ◽  
Vol 122 (23) ◽  
pp. 12243-12250 ◽  
Author(s):  
Yanbin Wang ◽  
Shayandev Sinha ◽  
Kunal Ahuja ◽  
Parth Rakesh Desai ◽  
Jiaqi Dai ◽  
...  

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Mireille Alhouayek ◽  
René Sorti ◽  
Jonathan D. Gilthorpe ◽  
Christopher J. Fowler

Biomaterials ◽  
2011 ◽  
Vol 32 (22) ◽  
pp. 5148-5157 ◽  
Author(s):  
Ling Xiao ◽  
Xiaoqin Xiong ◽  
Xiaohui Sun ◽  
Yanhong Zhu ◽  
Hao Yang ◽  
...  

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