Origin of Unusually High Fluorescence Anisotropy of 3-Hydroxyflavone in Water: Formation of Probe–Solvent Cage-like Cluster

2019 ◽  
Vol 124 (1) ◽  
pp. 173-180 ◽  
Author(s):  
Sinjan Das ◽  
Suman Chakrabarty ◽  
Nitin Chattopadhyay
Keyword(s):  
Fluorescence Anisotropy ◽  
Solvent Cage ◽  
Water Formation ◽  
High Fluorescence

scholarly journals “Where does the fluorescing moiety reside in a carbon dot?” – Investigations based on fluorescence anisotropy decay and resonance energy transfer dynamics

2018 ◽  
Vol 20 (4) ◽  
pp. 2251-2259 ◽  
Author(s):  
Ananya Das ◽  
Debjit Roy ◽  
Chayan K. De ◽  
Prasun K. Mandal
Keyword(s):  
Energy Transfer ◽  
Fluorescence Anisotropy ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Fluorescence Anisotropy Decay ◽  
Carbon Dot ◽  
Anisotropy Decay ◽  
High Fluorescence ◽  
Very High

It has been shown recently that aggregated dyes are responsible for very high fluorescence in a carbon dot (CD). Location of the fluorescing unit in a carbon dot could be shown.

Deactivation of the S,-State of w-Substituted 4-Dimethylamino-trans-Styrenes in Alkane Solutions

1991 ◽  
Vol 46 (12) ◽  
pp. 1043-1048
Author(s):  
A. Kawski ◽  
I. Gryczyński ◽  
K. Nowaczyk ◽  
P. Bojarski ◽  
J. Lichacz
Keyword(s):  
Excited State ◽  
Double Bond ◽  
Fluorescence Quenching ◽  
Conformational Changes ◽  
Linear Dependence ◽  
Fluorescence Anisotropy ◽  
Intersystem Crossing ◽  
Strong Fluorescence ◽  
Fluorescence Depolarization ◽  
High Fluorescence

Abstract Deactivation of three co-substituted acceptors in 4-dimethylamino-trans-styrenes (P(S)Ph2 (la), P(0)Ph2 (2a) and SO2CH3 (3a)), dissolved in «-paraffins (from n = 5 to n = 16) at 293 K, was investigated. Trans-cis isomerization and intersystem crossing are the main processes responsible for radiationless deactivation of the S1 excited state. High fluorescence anisotropy, r, observed in low-viscous «-paraffins, is due to strong fluorescence quenching resulting in the considerable shortening of the lifetime τ of these molecules. The fluorescence depolarization which occurs when lowering the viscosity, η, of the solution is caused by Brownian rotations and conformational changes due to fast adiabatic twisting of the planar trans-S1 form around the double bond, leading to the formation of the perp.-S1 structure with perpendicularly oriented parts of the molecule, and to the concomitant change in the transition moment direction. Linear dependence of τ2{r0/r - 1) on η - τ in the whole viscosity range was only observed for molecule 3a

Lattice Distortion in Mixed-Anion Lead Halide Perovskite Nanorods Leads to their High Fluorescence Anisotropy

2020 ◽  
Vol 2 (7) ◽  
pp. 814-820
Author(s):  
Yongjiang Dou ◽  
Fan Cao ◽  
Tetiana Dudka ◽  
Yunguo Li ◽  
Sheng Wang ◽  
...  
Keyword(s):  
Fluorescence Anisotropy ◽  
Lattice Distortion ◽  
Halide Perovskite ◽  
High Fluorescence ◽  
Lead Halide

High Fluorescence Anisotropy of Thioflavin T in Aqueous Solution Resulting from Its Molecular Rotor Nature

2015 ◽  
Vol 88 (1) ◽  
pp. 718-724 ◽  
Author(s):  
Irina M. Kuznetsova ◽  
Anna I. Sulatskaya ◽  
Alexander A. Maskevich ◽  
Vladimir N. Uversky ◽  
Konstantin K. Turoverov
Keyword(s):  
Aqueous Solution ◽  
Fluorescence Anisotropy ◽  
Thioflavin T ◽  
Molecular Rotor ◽  
High Fluorescence

Design and Development of Fe-Catalyzed Intra- and Intermolecular Carbofunctionalization of Vinyl Cyclopropanes

2019 ◽  
Author(s):  
Lei Liu ◽  
Wes Lee ◽  
Mingbin Yuan ◽  
Chris Acha ◽  
Michael B. Geherty ◽  
...  
Keyword(s):  
Bond Formation ◽  
Cross Coupling ◽  
Alkyl Halides ◽  
Grignard Reagents ◽  
Mechanistic Studies ◽  
Radical Intermediates ◽  
Design And Implementation ◽  
Solvent Cage ◽  
Radical Cascade ◽  
Radical Processes

Design and implementation of the first (asymmetric) Fe-catalyzed intra- and intermolecular difunctionalization of vinyl cyclopropanes (VCPs) with alkyl halides and aryl Grignard reagents has been realized via a mechanistically driven approach. Mechanistic studies support the diffusion of the alkyl radical intermediates out of the solvent cage to participate in an intra- or -intermolecular radical cascade with the VCP followed by re-entering the Fe radical cross-coupling cycle to undergo selective C(sp2)-C(sp3) bond formation. Overall, we provide new design principles for Fe-mediated radical processes and underscore the potential of using combined computations and experiments to accelerate the development of challenging transformations.

scholarly journals Malignant pericardial effusion complicated by cardiac tamponade under atezolizumab

2021 ◽  
Vol 9 ◽  
pp. 2050313X2110360
Author(s):  
Lardinois Benjamin ◽  
Goeminne Jean-Charles ◽  
Miller Laurence ◽  
Randazzo Adrien ◽  
Laurent Terry ◽  
...  
Keyword(s):  
Pericardial Effusion ◽  
Cardiac Tamponade ◽  
Cardiac Toxicity ◽  
Checkpoint Inhibitors ◽  
Final Diagnosis ◽  
Pericardial Fluid ◽  
Malignant Pericardial Effusion ◽  
Typical Cell ◽  
High Fluorescence ◽  
Tomography Scan

Immune-related adverse events including cardiac toxicity are increasingly described in patients receiving immune checkpoint inhibitors. We described a malignant pericardial effusion complicated by a cardiac tamponade in an advanced non-small cell lung cancer patient who had received five infusions of atezolizumab, a PDL-1 monoclonal antibody, in combination with cabozantinib. The definitive diagnosis was quickly made by cytology examination showing typical cell abnormalities and high fluorescence cell information provided by the hematology analyzer. The administration of atezolizumab and cabozantinib was temporarily discontinued due to cardiogenic hepatic failure following cardiac tamponade. After the re-initiation of the treatment, pericardial effusion relapsed. In this patient, the analysis of the pericardial fluid led to the final diagnosis of pericardial tumor progression. This was afterwards confirmed by the finding of proliferating intrapericardial tissue by computed tomography scan and ultrasound. This report emphasizes the value of cytology analysis performed in a hematology laboratory as an accurate and immediate tool for malignancy detection in pericardial effusions.

scholarly journals Detection of metal ions in biological systems: A review

2020 ◽  
Vol 39 (1) ◽  
pp. 231-246 ◽  
Author(s):  
Xian Zheng ◽  
Wenyu Cheng ◽  
Chendong Ji ◽  
Jin Zhang ◽  
Meizhen Yin
Keyword(s):  
Metal Ions ◽  
Metal Ion ◽  
Metabolic Regulation ◽  
Organic Dyes ◽  
Biological Systems ◽  
High Sensitivity ◽  
Transportation Energy ◽  
Material Transportation ◽  
High Fluorescence ◽  
Metal Ion Detection

Abstract Metal ions are widely present in biological systems and participate in many critical biochemical processes such as material transportation, energy conversion, information transmission and metabolic regulation, making them indispensable substance in our body. They can cause health problems when deficiency or excess occurs. To understand various metabolic processes and facilitate diseases diagnosis, it is very important to measure the content and monitor the distribution of metal ions in individual cells, tissues and whole organisms. Among the various methods for metal ion detection, fluorescent sensors with organic dyes have attracted tremendous attention due to many advantages such as high fluorescence quantum yield, facile modification approaches and biocompatibility in addition to operation ease, high sensitivity, fast detection speed, and real-time detection. This review summarizes the recent progress on the detection and imaging of the metal ions in biological systems including Na+, K+, Ca2+, Mg2+, Fe2+/Fe3+, Zn2+, and Cu2+ provides an opinion on remaining challenges to be addressed in this field.

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