Branched-Chain Fatty Acid Content Modulates Structure, Fluidity, and Phase in Model Microbial Cell Membranes

2019 ◽  
Vol 123 (27) ◽  
pp. 5814-5821 ◽  
Author(s):  
Barmak Mostofian ◽  
Tony Zhuang ◽  
Xiaolin Cheng ◽  
Jonathan D. Nickels
1998 ◽  
Vol 180 (19) ◽  
pp. 5269-5272 ◽  
Author(s):  
Geoffrey Bartholomeusz ◽  
Yanglong Zhu ◽  
John Downard

ABSTRACT We compared the cellular fatty acid profiles of Myxococcus xanthus cells grown in either a Casitone-based complex medium or a chemically defined medium. The cells grown in the complex medium had a much higher content of the abundant branched-chain fatty acidiso-15:0 and several other branched-chain species. The higher branched-chain fatty acid content of the cells grown in the complex medium was dependent on the esg locus, which encodes the E1α and E1β components of a branched-chain keto acid dehydrogenase (BCKAD) multienzyme complex involved in branched-chain fatty acid biosynthesis. Cells grown in the complex medium were also found to have a higher level of esg transcription and more BCKAD enzyme activity than cells from the chemically defined medium. The level of esg transcription appears to be an important factor in the growth medium-dependent regulation of the M. xanthus branched-chain fatty acid content.


Lipids ◽  
2011 ◽  
Vol 46 (7) ◽  
pp. 569-576 ◽  
Author(s):  
R. R. Ran-Ressler ◽  
D. Sim ◽  
A. M. O’Donnell-Megaro ◽  
D. E. Bauman ◽  
D. M. Barbano ◽  
...  

2018 ◽  
Vol 7 (3) ◽  
pp. 8
Author(s):  
Andrew Paul Smith ◽  
Eddie Deaville ◽  
Glenn Gibson

Research has shown that consumption of high fiber breakfast cereal is associated with improved subjective well-being, especially increased energy. One possible explanation of these results is through metabolism by gut bacteria and concomitant production of metabolites that influence psychological and gastrointestinal (GI) welfare. This was examined in the present study to determine whether consumption of wheat bran could modulate the composition of the GI microbiota. This human volunteer study (20 volunteers) involved the comparison of three breakfast cereals, All-Bran, Bran Flakes and Cornflakes (60 g/d). The study involved a 14-day baseline phase (no breakfast cereals) and an eight-week experimental phase. Each cereal was consumed for 14 days. A seven-day washout period (no cereals) was carried out between each successive cereal condition. Faecal samples were collected every seven days. Enumeration of predominant faecal bacterial populations (bacteroides, bifidobacteria, clostridia, lactobacilli and eubacteria) was carried out using the culture independent fluorescent in situ hybridisation (FISH) technique. Faecal short chain fatty acid content was also determined. The volunteers completed a battery of questionnaires to assess fatigue/energy, subjective mood, physical and mental health, bowel function and fiber intake. The results showed that in general there was no overall significant effect of breakfast cereal type on the faecal bacterial populations studied. There was also no major effect of breakfast type on short chain fatty acid content. The high-fiber conditions (All-Bran and Bran Flakes) were associated with less fatigue, a significant reduction in cognitive difficulties, looser stools, more motions and feeling more energised.


PLoS ONE ◽  
2012 ◽  
Vol 7 (11) ◽  
pp. e49261 ◽  
Author(s):  
Sophie Jasinski ◽  
Alain Lécureuil ◽  
Martine Miquel ◽  
Olivier Loudet ◽  
Sylvain Raffaele ◽  
...  

2015 ◽  
Vol 47 ◽  
pp. 488
Author(s):  
Jacob M. Allen ◽  
Matthew R. Panasevich ◽  
Brandt D. Pence ◽  
Yi Sun ◽  
Ryan N. Dilger ◽  
...  

1995 ◽  
Vol 68 (2) ◽  
pp. 241-248 ◽  
Author(s):  
Anna M Berggren ◽  
Inger M E Björck ◽  
E Margareta G L Nyman ◽  
Bjørn O Eggum

2017 ◽  
Vol 174 (1) ◽  
pp. 97-109 ◽  
Author(s):  
Umidjon Iskandarov ◽  
Jillian E. Silva ◽  
Hae Jin Kim ◽  
Mariette Andersson ◽  
Rebecca E. Cahoon ◽  
...  

Euphytica ◽  
2008 ◽  
Vol 164 (2) ◽  
pp. 583-592 ◽  
Author(s):  
Daren Coonrod ◽  
Mark A. Brick ◽  
Patrick F. Byrne ◽  
Lorin DeBonte ◽  
Zhizheng Chen

2016 ◽  
Vol 7 (10) ◽  
pp. 4460-4467 ◽  
Author(s):  
María Jesús Periago ◽  
Gala Martín-Pozuelo ◽  
Rocío González-Barrio ◽  
Marina Santaella ◽  
Victoria Gómez ◽  
...  

The plausible mechanisms of the hypocholesterolemic effect of tomato juice have been studied evaluating the activity of HMGCR in liver and the propionic acid formation in feces.


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