Influence of Monovalent Cation Size on Nanodomain Formation in Anionic–Zwitterionic Mixed Bilayers

2017 ◽  
Vol 121 (4) ◽  
pp. 787-799 ◽  
Author(s):  
Sai J. Ganesan ◽  
Hongcheng Xu ◽  
Silvina Matysiak
Keyword(s):  
Monovalent Cation ◽  
Cation Size

Monovalent Cation Size and DNA Conformational Stability

Biochemistry ◽  
2011 ◽  
Vol 50 (15) ◽  
pp. 3084-3094 ◽  
Author(s):  
Earle Stellwagen ◽  
Joseph M. Muse ◽  
Nancy C. Stellwagen
Keyword(s):  
Conformational Stability ◽  
Monovalent Cation ◽  
Cation Size

scholarly journals Structural Characterization and Comparison of Monovalent Cation-Exchanged Zeolite-W

Materials ◽  
2020 ◽  
Vol 13 (17) ◽  
pp. 3684
Author(s):  
Donghoon Seoung ◽  
Hyeonsu Kim ◽  
Pyosang Kim ◽  
Chihyun Song ◽  
Suhyeong Lee ◽  
...  
Keyword(s):  
Volume Expansion ◽  
Structural Changes ◽  
Monovalent Cation ◽  
Water Molecules ◽  
Channel Opening ◽  
Group A ◽  
Framework Species ◽  
Cation Size ◽  
Cell Volumes ◽  
Channel Unit

We report comparative structural changes of potassium-contained zeolite-W (K-MER, structural analogue of natural zeolite merlinoite) and monovalent extra-framework cation (EFC)-exchanged M-MERs (M = Li+, Na+, Ag+, and Rb+). High-resolution synchrotron X-ray powder diffraction study precisely determines that crystal symmetry of MERs is tetragonal (I4/mmm). Rietveld refinement results reveal that frameworks of all MERs are geometrically composed of disordered Al/Si tetrahedra, bridged by linkage oxygen atoms. We observe a structural relationship between a group of Li-, Na-, and Ag-MER and the group of K- and Rb-MER by EFC radius and position of M(1) site inside double 8-membered ring unit (d8r). In the former group, a-axes decrease reciprocally, c-axes gradually extend by EFC size, and M(1) cations are located at the middle of the d8r. In the latter group, a- and c-axes lengths become longer and shorter, respectively, than axes of the former group, and these axial changes come from middle-to-edge migration of M(1) cations inside the d8r channel. Unit cell volumes of the Na-, Ag-, and K-MER are ca. 2005 Å3, and the volume expansion in the MER series is limited by EFC size, the number of water molecules, and the distribution of extra-framework species inside the MER channel. EFC sites of M(1) and M(2) show disordered and ordered distribution in the former group, and all EFC sites change to disordered distribution after migration of the M(1) site in the latter group. The amount of water molecules and porosities are inversely proportional to EFC size due to the limitation of volume expansion of MERs. The channel opening area of a pau composite building unit and the amount of water molecules are universally related as a function of cation size because water molecules are mainly distributed inside a pau channel.

scholarly journals The Influence of Monovalent Cation Size on the Stability of RNA Tertiary Structures

2009 ◽  
Vol 390 (4) ◽  
pp. 791-804 ◽  
Author(s):  
Dominic Lambert ◽  
Desirae Leipply ◽  
Ross Shiman ◽  
David E. Draper
Keyword(s):  
Monovalent Cation ◽  
Tertiary Structures ◽  
The Stability ◽  
Cation Size

scholarly journals TRPM4 in Cancer—A New Potential Drug Target

Biomolecules ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 229
Author(s):  
Anna Borgström ◽  
Christine Peinelt ◽  
Paulina Stokłosa
Keyword(s):  
Anticancer Drug ◽  
Drug Target ◽  
Transient Receptor Potential ◽  
Human Cancer ◽  
Receptor Potential ◽  
B Cell Lymphoma ◽  
Underlying Mechanism ◽  
Monovalent Cation ◽  
Transient Receptor Potential Melastatin ◽  
And Migration

Transient receptor potential melastatin 4 (TRPM4) is widely expressed in various organs and associated with cardiovascular and immune diseases. Lately, the interest in studies on TRPM4 in cancer has increased. Thus far, TRPM4 has been investigated in diffuse large B-cell lymphoma, prostate, colorectal, liver, breast, urinary bladder, cervical, and endometrial cancer. In several types of cancer TRPM4 is overexpressed and contributes to cancer hallmark functions such as increased proliferation and migration and cell cycle shift. Hence, TRPM4 is a potential prognostic cancer marker and a promising anticancer drug target candidate. Currently, the underlying mechanism by which TRPM4 contributes to cancer hallmark functions is under investigation. TRPM4 is a Ca2+-activated monovalent cation channel, and its ion conductivity can decrease intracellular Ca2+ signaling. Furthermore, TRPM4 can interact with different partner proteins. However, the lack of potent and specific TRPM4 inhibitors has delayed the investigations of TRPM4. In this review, we summarize the potential mechanisms of action and discuss new small molecule TRPM4 inhibitors, as well as the TRPM4 antibody, M4P. Additionally, we provide an overview of TRPM4 in human cancer and discuss TRPM4 as a diagnostic marker and anticancer drug target.

Cation-size mismatch and interface stabilization for efficient NiOx-based inverted perovskite solar cells with 21.9% efficiency

Nano Energy ◽  
2021 ◽  
pp. 106285
Author(s):  
Yousheng Wang ◽  
Hui Ju ◽  
Tahmineh Mahmoudi ◽  
Chong Liu ◽  
Cuiling Zhang ◽  
...  
Keyword(s):  
Solar Cells ◽  
Perovskite Solar Cells ◽  
Size Mismatch ◽  
Cation Size

scholarly journals Specific Ion Effects on the Behavior of Mixtures of Sodium Iso-Butyl Xanthate and Sodium Diethyl Dithiophosphate during the Flotation of a Cu-Ni-PGM Ore: Effects of CaCl2 and NaCl

2021 ◽  
Vol 6 (1) ◽  
pp. 22
Author(s):  
Malibongwe S. Manono ◽  
Katlego Matibidi ◽  
Kirsten C. Corin ◽  
Catherine K. Thubakgale ◽  
Iyiola O. Otunniyi ◽  
...  
Keyword(s):  
Froth Flotation ◽  
Monovalent Cation ◽  
Process Water ◽  
Polyvalent Cation ◽  
Flotation Reagents ◽  
Sulfide Flotation ◽  
Froth Stability ◽  
Ion Effects ◽  
The Relationship ◽  
Diethyl Dithiophosphate

Inorganic electrolytes present in the process water used during froth flotation may have both beneficial and detrimental effects. These effects are said to be ion specific, as some ions may result in enhanced froth stability, increased mineral recoveries and decreased concentrate grades, while others may bring the opposite effects. Onsite process water quality variations have intensified the need to understand the relationship between inorganic electrolytes and flotation reagents on flotation performance. The use of mixtures of thiol collectors in sulfide flotation is a common practice across the globe; however, very few investigations have considered these in process waters of varying compositions. This study considers the effect of common cations, Na+ and Ca2+, in process water on the behavior of mixtures of thiol collectors. Single-salt solutions of NaCl and CaCl2 at an ionic strength of 0.0213 mol·dm−3 were used to investigate the behavior of mixtures of two thiol collectors. These were carefully selected to understand how mixtures of thiol collectors behave in the presence of a monovalent cation versus a polyvalent cation. Bench-scale froth flotation tests were conducted using a Cu-Ni-PGM ore from the Merensky Reef. The results have shown that the divalent cation, Ca2+, resulted in higher %Cu and %Ni recoveries at all collector mixtures compared to the monovalent cation, Na+. The concentrate grades were, however, slightly compromised, as slightly more gangue reported to the concentrate in the presence of Ca2+. This behavior is attributed to the effect of polyvalent cations on bubble coalescence and froth stability.

TRPC1, TRPC3, and TRPC4 in Rat Orofacial Structures

2017 ◽  
Vol 204 (5-6) ◽  
pp. 293-303 ◽  
Author(s):  
Masatoshi Fujita ◽  
Tadasu Sato ◽  
Takehiro Yajima ◽  
Eiji Masaki ◽  
Hiroyuki Ichikawa
Keyword(s):  
Transient Receptor Potential ◽  
Sympathetic Neurons ◽  
Receptor Potential ◽  
Monovalent Cation ◽  
Calcitonin Gene ◽  
Cervical Ganglion ◽  
Parasympathetic Neurons ◽  
Transient Receptor ◽  
And Function ◽  
And Control

TRPC (transient receptor potential cation channel subfamily C) members are nonselective monovalent cation channels and control Ca2+ inflow. In this study, immunohistochemistry for TRPC1, TRPC3, and TRPC4 was performed on rat oral and craniofacial structures to elucidate their distribution and function in the peripheries. In the trigeminal ganglion (TG), 56.1, 84.1, and 68.3% of sensory neurons were immunoreactive (IR) for TRPC1, TRPC3, and TRPC4, respectively. A double immunofluorescence method revealed that small to medium-sized TG neurons co-expressed TRPCs and calcitonin gene-related peptide. In the superior cervical ganglion, all sympathetic neurons showed TRPC1 and TRPC3 immunoreactivity. Parasympathetic neurons in the submandibular ganglion, tongue, and parotid gland were TRPC1, TRPC3, and TRPC4 IR. Gustatory and olfactory cells were also IR for TRPC1, TRPC3, and/or TRPC4. In the musculature, motor endplates expressed TRPC1 and TRPC4 immunoreactivity. It is likely that TRPCs are associated with sensory, autonomic, and motor functions in oral and craniofacial structures.

Sign in / Sign up

Export Citation Format

Share Document