Toward a Multipathway Perspective: pH-Dependent Kinetic Selection of Competing Pathways and the Role of the Internal Glutamate in Cl–/H+ Antiporters

AbstractImmunosuppression permits graft survival after transplantation and consequently a longer and better life. On the other hand, it increases the risk of infection, for instance with cytomegalovirus (CMV). However, the various available immunosuppressive therapies differ in this regard. One of the first clinical trials using de novo everolimus after kidney transplantation [1] already revealed a considerably lower incidence of CMV infection in the everolimus arms than in the mycophenolate mofetil (MMF) arm. This result was repeatedly confirmed in later studies [2–4]. Everolimus is now considered a substance with antiviral properties. This article is based on the expert meeting “Posttransplant CMV infection and the role of immunosuppression”. The expert panel called for a paradigm shift: In a CMV prevention strategy the targeted selection of the immunosuppressive therapy is also a key element. For patients with elevated risk of CMV, mTOR inhibitor-based immunosuppression is advantageous as it is associated with a significantly lower incidence of CMV events.

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Energy Efficiency Analysis in ERA using NFL-BA Algorithm

International Journal of Scientific Research in Science and Technology ◽

10.32628/ijsrst207477 ◽

2020 ◽

pp. 340-348

Author(s):

Palky Mehta ◽

H. L. Sharma

Keyword(s):

Cluster Head ◽

Vital Role ◽

Wireless Sensor ◽

Energy Usage ◽

Cluster Heads ◽

Comparison Results ◽

Current Scenario ◽

Energy Efficiency Analysis ◽

Selection Of

In the current scenario of Wireless Sensor Network (WSN), power consumption is the major issue associated with nodes in WSN. LEACH technique plays a vital role of clustering in WSN and reduces the energy usage effectively. But LEACH has its own limitation in order to search cluster head nodes which are randomly distributed over the network. In this paper, ERA-NFL- BA algorithm is being proposed for selects the cluster heads in WSN. This algorithm help in selection of cluster heads can freely transform from global search to local search. At the end, a comparison has been done with earlier researcher using protocol ERA-NFL, which clearly shown that proposed Algorithm is best suited and from comparison results that ERA-NFL-BA has given better performance.

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Tauchnitz for Translators. The Circulation of English-language Literature in Finland

Comparative Critical Studies ◽

10.3366/ccs.2019.0325 ◽

2019 ◽

Vol 16 (2-3) ◽

pp. 161-179

Author(s):

Outi Paloposki

Keyword(s):

Foreign Language ◽

English Language ◽

Book History ◽

Language Skills ◽

Point Of View ◽

Book Production ◽

German Publisher ◽

Language Literature ◽

Selection Of

The article looks at book production and circulation from the point of view of translators, who, as purchasers and readers of foreign-language books, are an important mediating force in the selection of literature for translation. Taking the German publisher Tauchnitz's series ‘Collection of British Authors’ and its circulation in Finland in the nineteenth and early twentieth century as a case in point, the article argues that the increased availability of English-language books facilitated the acquiring and honing of translators' language skills and gradually diminished the need for indirect translating. Book history and translation studies meet here in an examination of the role of the Collection in Finnish translators' work.

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The Adult as Foe or Friend?: Childism in Guus Kuijer's Criticism and Fiction

International Research in Children s Literature ◽

10.3366/ircl.2013.0099 ◽

2013 ◽

Vol 6 (2) ◽

pp. 205-217 ◽

Cited By ~ 3

Author(s):

Vanessa Joosen

Keyword(s):

Children's Literature ◽

Children’S Literature ◽

Age Groups ◽

Children's Books ◽

Children’S Books ◽

Memorial Award ◽

Adult Reader ◽

Shed Light ◽

Selection Of

Compared to the attention that children's literature scholars have paid to the construction of childhood in children's literature and the role of adults as authors, mediators and readers of children's books, few researchers have made a systematic study of adults as characters in children's books. This article analyses the construction of adulthood in a selection of texts by the Dutch author and Astrid Lindgren Memorial Award winner Guus Kuijer and connects them with Elisabeth Young-Bruehl's recent concept of ‘childism’ – a form of prejudice targeted against children. Whereas Kuijer published a severe critique of adulthood in Het geminachte kind [The despised child] (1980), in his literary works he explores a variety of positions that adults can take towards children, with varying degrees of childist features. Such a systematic and comparative analysis of the way grown-ups are characterised in children's texts helps to shed light on a didactic potential that materialises in different adult subject positions. After all, not only literary and artistic aspects of children's literature may be aimed at the adult reader (as well as the child), but also the didactic aspect of children's books can cross over between different age groups.

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Phytocenotic selection of perennial grasses as a factor of increasing the productivity of mixed agrophytocenoses

сборник статей всероссийской научной конференции с международным участием "Растениеводство и луговодство" ◽

10.26897/978-5-9675-1762-4-2020-96 ◽

2020 ◽

Author(s):

V.N. Zolotarev ◽

◽

I.S. Ivanov ◽

O.N. Lyubtseva

Keyword(s):

Perennial Grasses ◽

New Varieties ◽

The Creation ◽

High Yields ◽

Selection Of

Based on the analysis of data available in the literature and our own experimental material on phytocenotic selection of the stony stalk (Bromopsis inermis Holub.) the important role of competition between plants in the field for the creation of new varieties of perennial grasses that provide high yields of feed polyvid agrophytocenoses is shown.

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SISTEM PENDUKUNG KEPUTUSAN PEMILIHAN GURU BERPRESTASI KOTA MEDAN MENERAPKAN METODE PREFERENCES SELECTION INDEX (STUDI KASUS : DINAS PENDIDIKAN KOTA MEDAN)

KOMIK (Konferensi Nasional Teknologi Informasi dan Komputer) ◽

10.30865/komik.v2i1.921 ◽

2018 ◽

Vol 2 (1) ◽

Author(s):

Fajar Syahputra ◽

Mesran Mesran ◽

Ikhwan Lubis ◽

Agus Perdana Windarto

Keyword(s):

Decision Making ◽

Decision Support ◽

Decision Support System ◽

Support System ◽

Formal Education ◽

Basic Education ◽

Selection Index ◽

Main Task ◽

Selection Of

The teacher is a major milestone in the world of education, the ability and achievement of students cannot be separated from the role of a teacher in teaching and guiding students. Based on the Law of the Republic of Indonesia No. 14 of 2005 concerning Teachers and Lecturers, in Article 1 explained that teachers are professional educators with the main task of educating, teaching, guiding, directing, training, evaluating, and evaluating students in early childhood education through formal education, basic education and education medium. Whereas in Article 4 of the Act, it is explained that the position of teachers as professionals serves to enhance the dignity and role of teachers as learning agents to function to improve the quality of national education.Decision making is an election process, among various alternatives that aim to meet one or several targets. The decision-making system has 4 phases, namely intelligence, design, choice and implementation. These phases are the basis for decision making, which ends with a recommendation.The Preferences Selection Index (PSI) method is a rarely used decision support system method. This method is a method developed by stevanie and Bhatt (2010) to solve the Multi Criteria Decision Making (MCDM). With the right consideration, this method can be one of the tools to determine policies in decision-making systems, especially the selection of outstanding teachers. Determination of policies taken as a basis for decision making, must use criteria that can be defined clearly and objectively.Keywords: Decision Support System, PSI, Selection of Achieving Teachers

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Pulvino-cortical interaction: an integrative role in the control of attention

10.31234/osf.io/g4fn7 ◽

2019 ◽

Author(s):

Alexia Bourgeois ◽

Carole Guedj ◽

Emmanuel Carrera ◽

Patrik Vuilleumier

Keyword(s):

Executive Control ◽

Sensory Information ◽

Relevant Information ◽

Cortical Circuits ◽

Attention And Executive Control ◽

Neural Communication ◽

Subcortical Regions ◽

Theoretical Proposal ◽

Selection Of

Selective attention is a fundamental cognitive function that guides behavior by selecting and prioritizing salient or relevant sensory information of our environment. Despite early evidence and theoretical proposal pointing to an implication of thalamic control in attention, most studies in the past two decades focused on cortical substrates, largely ignoring the contribution of subcortical regions as well as cortico-subcortical interactions. Here, we suggest a key role of the pulvinar in the selection of salient and relevant information via its involvement in priority maps computation. Prioritization may be achieved through a pulvinar- mediated generation of alpha oscillations, which may then modulate neuronal gain in thalamo-cortical circuits. Such mechanism might orchestrate the synchrony of cortico-cortical interaction, by rendering neural communication more effective, precise and selective. We propose that this theoretical framework will support a timely shift from the prevailing cortico- centric view of cognition to a more integrative perspective of thalamic contributions to attention and executive control processes.

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