Diverse Native Ensembles Dictate the Differential Functional Responses of Nuclear Receptor Ligand-Binding Domains

2021 ◽  
Vol 125 (14) ◽  
pp. 3546-3555
Author(s):  
Soundhararajan Gopi ◽  
Bincy Lukose ◽  
Athi N. Naganathan
Keyword(s):  
Ligand Binding ◽  
Nuclear Receptor ◽  
Functional Responses ◽  
Receptor Ligand ◽  
Binding Domains

scholarly journals Helix 1/8 Interactions Influence the Activity of Nuclear Receptor Ligand-Binding Domains

2003 ◽  
Vol 17 (9) ◽  
pp. 1704-1714 ◽  
Author(s):  
Jason A. Holt ◽  
Thomas G. Consler ◽  
Shawn P. Williams ◽  
Andrea H. Ayscue ◽  
Lisa M. Leesnitzer ◽  
...  
Keyword(s):  
Ligand Binding ◽  
Nuclear Receptor ◽  
Receptor Ligand ◽  
Binding Domains

scholarly journals Dynamic Stabilization of Nuclear Receptor Ligand Binding Domains by Hormone or Corepressor Binding

2000 ◽  
Vol 6 (2) ◽  
pp. 245-253 ◽  
Author(s):  
Pavlos Pissios ◽  
Iphigenia Tzameli ◽  
Peter J. Kushner ◽  
David D. Moore
Keyword(s):  
Ligand Binding ◽  
Nuclear Receptor ◽  
Dynamic Stabilization ◽  
Receptor Ligand ◽  
Binding Domains

Conformational adaptation of nuclear receptor ligand binding domains to agonists: Potential for novel approaches to ligand design

2005 ◽  
Vol 93 (2-5) ◽  
pp. 127-137 ◽  
Author(s):  
Marie Togashi ◽  
Sabine Borngraeber ◽  
Ben Sandler ◽  
Robert J. Fletterick ◽  
Paul Webb ◽  
...  
Keyword(s):  
Ligand Binding ◽  
Nuclear Receptor ◽  
Ligand Design ◽  
Receptor Ligand ◽  
Binding Domains ◽  
Novel Approaches

scholarly journals Nuclear receptor ligand-binding domains: reduction of helix H12 dynamics to favour crystallization

2008 ◽  
Vol 64 (7) ◽  
pp. 614-616 ◽  
Author(s):  
Virginie Nahoum ◽  
Alexandra Lipski ◽  
Fabien Quillard ◽  
Jean-François Guichou ◽  
Yvan Boublik ◽  
...  
Keyword(s):  
Ligand Binding ◽  
Nuclear Receptor ◽  
Receptor Ligand ◽  
Binding Domains

scholarly journals Biochemical and NMR Mapping of the Interface between CREB-binding Protein and Ligand Binding Domains of Nuclear Receptor

2004 ◽  
Vol 280 (7) ◽  
pp. 5682-5692 ◽  
Author(s):  
Fabrice A. C. Klein ◽  
R. Andrew Atkinson ◽  
Noelle Potier ◽  
Dino Moras ◽  
Jean Cavarelli
Keyword(s):  
Ligand Binding ◽  
Nuclear Receptor ◽  
Binding Protein ◽  
Creb Binding Protein ◽  
Binding Domains
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