Dissecting Role of Charged Residue from Transmembrane Domain 5 of Latent Membrane Protein 1 via In Silico Simulations and Wet-Lab Experiments

2021 ◽  
Vol 125 (8) ◽  
pp. 2124-2133
Author(s):  
Yibo Wang ◽  
Bo Zhang ◽  
Cong Lin ◽  
Ying Liu ◽  
Min Yang ◽  
...  
Keyword(s):  
Membrane Protein ◽  
In Silico ◽  
Transmembrane Domain ◽  
Latent Membrane Protein ◽  
Latent Membrane Protein 1 ◽  
Charged Residue ◽  
Lab Experiments ◽  
Wet Lab

scholarly journals Targeting trimeric transmembrane domain 5 of oncogenic latent membrane protein 1 using a computationally designed peptide

2019 ◽  
Vol 10 (32) ◽  
pp. 7584-7590 ◽  
Author(s):  
Yibo Wang ◽  
Yinghua Peng ◽  
Bo Zhang ◽  
Xiaozheng Zhang ◽  
Hongyuan Li ◽  
...  
Keyword(s):  
Membrane Protein ◽  
In Silico ◽  
Transmembrane Domain ◽  
Transmembrane Helix ◽  
Latent Membrane Protein ◽  
Peptide Inhibitor ◽  
Latent Membrane Protein 1

A peptide inhibitor was designed in silico and validated experimentally to disrupt homotrimeric transmembrane helix assembly.

Pathogenic role of Epstein–Barr virus latent membrane protein-1 in the development of nasopharyngeal carcinoma

2013 ◽  
Vol 337 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Tomokazu Yoshizaki ◽  
Satoru Kondo ◽  
Naohiro Wakisaka ◽  
Shigeyuki Murono ◽  
Kazuhira Endo ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Membrane Protein ◽  
Epstein Barr Virus ◽  
Latent Membrane Protein ◽  
Latent Membrane Protein 1 ◽  
Pathogenic Role ◽  
Barr Virus ◽  
Epstein Barr ◽  
Virus Latent Membrane Protein
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