Probing n-Octyl α-d-Glycosides Using Deuterated Water in the Lyotropic Phase by Deuterium NMR

2021 ◽  
Author(s):  
Wan Farah Nasuha Wan Iskandar ◽  
Malinda Salim ◽  
Melonney Patrick ◽  
Bakir A. Timimi ◽  
N. Idayu Zahid ◽  
...  
Keyword(s):  
Deuterium Nmr ◽  
Deuterated Water

In vivo study of the biosynthesis of long-chain fatty acids using deuterated water

1995 ◽  
Vol 269 (2) ◽  
pp. E247-E252 ◽  
Author(s):  
H. O. Ajie ◽  
M. J. Connor ◽  
W. N. Lee ◽  
S. Bassilian ◽  
E. A. Bergner ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
De Novo ◽  
Chain Elongation ◽  
Deuterated Water ◽  
De Novo Synthesis ◽  
Isotopomer Distribution ◽  
Long Chain ◽  
Mass Isotopomer

To determine the contributions of preexisting fatty acid, de novo synthesis, and chain elongation in long-chain fatty acid (LCFA) synthesis, the synthesis of LCFAs, palmitate (16:0), stearate (18:0), arachidate (20:0), behenate (22:0), and lignocerate (24:0), in the epidermis, liver, and spinal cord was determined using deuterated water and mass isotopomer distribution analysis in hairless mice and Sprague-Dawley rats. Animals were given 4% deuterated water for 5 days or 8 wk in their drinking water. Blood was withdrawn at the end of these times for the determination of deuterium enrichment, and the animals were killed to isolate the various tissues for lipid extraction for the determination of the mass isotopomer distributions. The mass isotopomer distributions in LCFA were incompatible with synthesis from a single pool of primer. The synthesis of palmitate, stearate, arachidate, behenate, and lignocerate followed the expected biochemical pathways for the synthesis of LCFAs. On average, three deuterium atoms were incorporated for every addition of an acetyl unit. The isotopomer distribution resulting from chain elongation and de novo synthesis can be described by the linear combination of two binomial distributions. The proportions of preexisting, chain elongation, and de novo-synthesized fatty acids as a percentage of the total fatty acids were determined using multiple linear regression analysis. Fractional synthesis was found to vary, depending on the tissue type and the fatty acid, from 47 to 87%. A substantial fraction (24-40%) of the newly synthesized molecules was derived from chain elongation of unlabeled (recycled) palmitate.

scholarly journals Deuterated water imaging of the rat brain following metabolism of [ 2 H 7 ]glucose

2021 ◽  
Vol 85 (6) ◽  
pp. 3049-3059
Author(s):  
Rohit Mahar ◽  
Huadong Zeng ◽  
Anthony Giacalone ◽  
Mukundan Ragavan ◽  
Thomas H. Mareci ◽  
...  
Keyword(s):  
Rat Brain ◽  
Deuterated Water

scholarly journals Deuterium NMR of water in immobilized protein systems

1982 ◽  
Vol 38 (1) ◽  
pp. 47-52 ◽  
Author(s):  
B. Borah ◽  
R.G. Bryant
Keyword(s):  
Deuterium Nmr

Restricted Rotational Motion of InterlayerWaterMolecules in Vanadium Pentoxide Hydrate, V2O5·n D2O, as Studied by Deuterium NMR

2002 ◽  
Vol 57 (6-7) ◽  
pp. 419-424 ◽  
Author(s):  
Sadamu Takeda ◽  
Yuko Gotoh ◽  
Goro Maruta ◽  
Shuichi Takahara ◽  
Shigeharu Kittaka
Keyword(s):  
Double Layer ◽  
Vanadium Pentoxide ◽  
Rotational Motion ◽  
Interlayer Space ◽  
Layer Structure ◽  
Bond Distance ◽  
Adsorbed Water ◽  
Deuterium Nmr ◽  
Water Molecules ◽  
Layer Structures

The rotational behavior of the interlayer water molecules of deuterated vanadium pentoxide hydrate, V2O5.nD2O, was studied by solid-state deuterium NMR for the mono- and double-layer structures of the adsorbed water molecules. The rotational motion was anisotropic even at 355 K for both the mono- and double-layer structures. The 180° flipping motion about the C2-symmetry axis of the water molecule and the rotation around the figure axis, which makes an angle Ɵ with the C2-axis, occurred with the activation energy of (34±4) and (49±6) kJmol-1, respectively. The activation energies were almost independent of the mono- and double-layer structures of the water molecules, but the angle Ɵ made by the two axes varied from 33° for the monolayer to 25° for the double-layer at 230 K. The angle started to decrease above 250 K (e. g. the angle was 17 at 355 K for the double-layer structure). The results indicate that the average orientation of the water molecules in the two dimensional interlayer space depends on the layer structure and on the temperature. From the deuterium NMR spectrum at 130 K, the quadrupole coupling constant e2Qq/h = 240 kHz and the asymmetry parameter η= 0.12 were deduced. These values indicate the average hydrogen bond distance R(O H) = 2.0 Å for the D2O molecules in the 2D-interlayer space

Backbone dynamics of poly(isopropyl acrylate) in chloroform. A deuterium NMR study

1984 ◽  
Vol 17 (12) ◽  
pp. 2837-2846 ◽  
Author(s):  
Frank D. Blum ◽  
B. Durairaj ◽  
A. S. Padmanabhan
Keyword(s):  
Backbone Dynamics ◽  
Deuterium Nmr ◽  
Nmr Study

A deuterium NMR study of orientational order in camphor

1979 ◽  
Vol 67 (2-3) ◽  
pp. 459-462 ◽  
Author(s):  
Roderick E. Wasylishen ◽  
Brian A. Pettitt ◽  
John S. Lewis
Keyword(s):  
Orientational Order ◽  
Deuterium Nmr ◽  
Nmr Study

Segmental dynamics in the amorphous phase of nylon 66: solid state deuterium NMR

1990 ◽  
Vol 23 (8) ◽  
pp. 2169-2182 ◽  
Author(s):  
H. Miura ◽  
J. Hirschinger ◽  
Alan D. English
Keyword(s):  
Solid State ◽  
Amorphous Phase ◽  
Deuterium Nmr ◽  
Nylon 66 ◽  
Segmental Dynamics
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