Novel Method of Constructing Two-Dimensional Correlation Spectroscopy without Subtracting a Reference Spectrum

2018 ◽  
Vol 122 (3) ◽  
pp. 788-797 ◽  
Author(s):  
Anqi He ◽  
Yiwei Zeng ◽  
Xiaoyan Kang ◽  
Shigeaki Morita ◽  
Yizhuang Xu ◽  
...  
2013 ◽  
Vol 139 (1-4) ◽  
pp. 115-119 ◽  
Author(s):  
Anthea L. Fudge ◽  
Kerry L. Wilkinson ◽  
Renata Ristic ◽  
Daniel Cozzolino

2003 ◽  
Vol 57 (8) ◽  
pp. 991-995 ◽  
Author(s):  
Mirosław A. Czarnecki

It has been shown that for two-dimensional (2D) correlation analysis with a perturbation average, the first or the last spectrum in the data set as a reference provides identical qualitative results. On the other hand, selection of the reference spectrum significantly different from the spectra used for 2D correlation analysis may complicate interpretation of the contour plots and in consequence lead to erroneous results. The effect of noise is relatively small when 2D correlation spectra are calculated without the reference spectrum. For the other reference spectra the magnitude of the noise effect is comparable. In all cases, the asynchronous spectra are more strongly affected by the noise as compared to the synchronous spectra.


2004 ◽  
Vol 18 (1) ◽  
pp. 49-58 ◽  
Author(s):  
José Luis R. Arrondo ◽  
Ibon Iloro ◽  
Julián Aguirre ◽  
Félix M. Goñi

Two‒dimensional IR correlation spectroscopy (2D‒IR) is a novel method that provides the analysis of infrared spectra with the capacity to differentiate overlapping peaks and to distinguish between in‒phase and out‒of‒phase spectral responses. Artificial spectra originated from protein amide I band component parameters have been used to study their variation in the correlation maps. Using spectra composed of one, two or three Gaussian peaks, behaviour patterns of the bands in the synchronous and asynchronous maps have been originated, with changes in intensity, band position and bandwidth. Intensity changes produce high‒intensity spots in the synchronous spectra, whereas only noise is observed in the asynchronous spectra. Band shifting originates more complex patterns. In synchronous spectra, several spots are generated at the beginning and at the end of the shifting band. Also, characteristic asynchronous spectra with butterfly‒like shapes are formed showing the trajectory of the shift. Finally, synchronous maps corresponding to band broadening reveal several spots at peak inflection points, related to the zones with higher intensity variation. The asynchronous spectra are very complex but they follow a characteristic symmetric pattern. Furthermore, examples of maps obtained from polypeptides and proteins using temperature as the perturbing factor are interpreted in terms of the patterns obtained from artificial bands.


AIAA Journal ◽  
1997 ◽  
Vol 35 ◽  
pp. 909-912
Author(s):  
Ronald J. Epstein ◽  
John A. Rule ◽  
Donald B. Bliss

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kiyoshi Masuyama ◽  
Tomoaki Higo ◽  
Jong-Kook Lee ◽  
Ryohei Matsuura ◽  
Ian Jones ◽  
...  

AbstractIn contrast to hypertrophic cardiomyopathy, there has been reported no specific pattern of cardiomyocyte array in dilated cardiomyopathy (DCM), partially because lack of alignment assessment in a three-dimensional (3D) manner. Here we have established a novel method to evaluate cardiomyocyte alignment in 3D using intravital heart imaging and demonstrated homogeneous alignment in DCM mice. Whilst cardiomyocytes of control mice changed their alignment by every layer in 3D and position twistedly even in a single layer, termed myocyte twist, cardiomyocytes of DCM mice aligned homogeneously both in two-dimensional (2D) and in 3D and lost myocyte twist. Manipulation of cultured cardiomyocyte toward homogeneously aligned increased their contractility, suggesting that homogeneous alignment in DCM mice is due to a sort of alignment remodelling as a way to compensate cardiac dysfunction. Our findings provide the first intravital evidence of cardiomyocyte alignment and will bring new insights into understanding the mechanism of heart failure.


Author(s):  
Wenjing Ji ◽  
Guojie Zhao ◽  
Cong Guo ◽  
Li Fan ◽  
Hua Deng ◽  
...  
Keyword(s):  

Author(s):  
Alexey S. Kiryutin ◽  
Ivan V. Zhukov ◽  
Fabien Ferrage ◽  
G Bodenhausen ◽  
Alexandra V. Yurkovskaya ◽  
...  

A novel method dubbed ZULF-TOCSY results from the combination of Zero and Ultra-Low Field (ZULF) with high-field, high-resolution NMR, leading to a generalization of the concept of total correlation spectroscopy...


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