Photoredox Alkenylation of Carboxylic Acids and Peptides: Synthesis of Covalent Enzyme Inhibitors

Lisa Marie Kammer; Benjamin Lipp; Till Opatz

doi:10.1021/acs.joc.8b02759

Photoredox Alkenylation of Carboxylic Acids and Peptides: Synthesis of Covalent Enzyme Inhibitors

The Journal of Organic Chemistry ◽

10.1021/acs.joc.8b02759 ◽

2018 ◽

Vol 84 (5) ◽

pp. 2379-2392 ◽

Cited By ~ 5

Author(s):

Lisa Marie Kammer ◽

Benjamin Lipp ◽

Till Opatz

Keyword(s):

Carboxylic Acids ◽

Enzyme Inhibitors ◽

Peptides Synthesis

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Irreversible enzyme inhibitors. 191. Hydrophobic bonding to some dehydrogenases by 6-, 7-, or 8-substituted-4-hydroxyquinoline-3-carboxylic acids

Journal of Medicinal Chemistry ◽

10.1021/jm00273a007 ◽

1972 ◽

Vol 15 (3) ◽

pp. 235-237 ◽

Cited By ~ 7

Author(s):

B. R. Baker ◽

Ray R. Bramhall

Keyword(s):

Carboxylic Acids ◽

Enzyme Inhibitors ◽

Hydrophobic Bonding

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Irreversible enzyme inhibitors. 190. Inhibition of some dehydrogenases by 1-substituted-1,4-dihydro-4-quinolone-3-carboxylic acids

Journal of Medicinal Chemistry ◽

10.1021/jm00273a006 ◽

1972 ◽

Vol 15 (3) ◽

pp. 233-235 ◽

Cited By ~ 8

Author(s):

B. R. Baker ◽

Ray R. Bramhall

Keyword(s):

Carboxylic Acids ◽

Enzyme Inhibitors

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7-SUBSTITUTED-4-HYROXYQUINOLINE-3-CARBOXYLIC ACIDS AS DEHYDROGENASE ENZYME INHIBITORS

Chemical Structure–Biological Activity Relationships: Quantitative Approaches ◽

10.1016/b978-0-08-026388-5.50014-6 ◽

1980 ◽

pp. 91-100

Author(s):

Eugene A. Coats ◽

Kishor J. Shah ◽

Stanley R. Milstein ◽

Clara S. Genther ◽

Dilip M. Nene ◽

...

Keyword(s):

Carboxylic Acids ◽

Enzyme Inhibitors ◽

Dehydrogenase Enzyme

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ChemInform Abstract: (MERCAPTOPROPANOYL)INDOLINE-2-CARBOXYLIC ACIDS AND RELATED COMPOUNDS AS POTENT ANGIOTENSIN CONVERTING ENZYME INHIBITORS AND ANTIHYPERTENSIVE AGENTS

Chemischer Informationsdienst ◽

10.1002/chin.198334183 ◽

1983 ◽

Vol 14 (34) ◽

Author(s):

D. H. KIM ◽

C. J. GUINOSSO ◽

G. C. JUN. BUZBY ◽

D. R. HERBST ◽

R. J. MCCAULLY ◽

...

Keyword(s):

Angiotensin Converting Enzyme ◽

Carboxylic Acids ◽

Enzyme Inhibitors ◽

Antihypertensive Agents ◽

Angiotensin Converting Enzyme Inhibitors ◽

Converting Enzyme ◽

Converting Enzyme Inhibitors ◽

Related Compounds

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Irreversible enzyme inhibitors. 194. Hydrophobic bonding to some dehydrogenases by substituted 5-phenylethyl-4-hydroxyquinoline-3-carboxylic acids

Journal of Medicinal Chemistry ◽

10.1021/jm00279a015 ◽

1972 ◽

Vol 15 (9) ◽

pp. 937-940 ◽

Cited By ~ 4

Author(s):

B. R. Baker ◽

Ray R. Bramhall

Keyword(s):

Carboxylic Acids ◽

Enzyme Inhibitors ◽

Hydrophobic Bonding

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(Mercaptopropanoyl)indoline-2-carboxylic acids and related compounds as potent angiotensin converting enzyme inhibitors and antihypertensive agents

Journal of Medicinal Chemistry ◽

10.1021/jm00357a014 ◽

1983 ◽

Vol 26 (3) ◽

pp. 394-403 ◽

Cited By ~ 42

Author(s):

Dong H. Kim ◽

Charles J. Guinosso ◽

George C. Buzby ◽

David R. Herbst ◽

Ronald J. McCaully ◽

...

Keyword(s):

Angiotensin Converting Enzyme ◽

Carboxylic Acids ◽

Enzyme Inhibitors ◽

Antihypertensive Agents ◽

Angiotensin Converting Enzyme Inhibitors ◽

Converting Enzyme ◽

Converting Enzyme Inhibitors ◽

Related Compounds

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Irreversible enzyme inhibitors. 189. Inhibition of some dehydrogenases by derivatives of 4-hydroxyquinoline-2- and -3-carboxylic acids

Journal of Medicinal Chemistry ◽

10.1021/jm00273a005 ◽

1972 ◽

Vol 15 (3) ◽

pp. 230-233 ◽

Cited By ~ 25

Author(s):

B. R. Baker ◽

Ray R. Bramhall

Keyword(s):

Carboxylic Acids ◽

Enzyme Inhibitors ◽

Derivatives Of

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Irreversible enzyme inhibitors. 192. Hydrophobic bonding to some dehydrogenases with 5-substituted-4-hydroxyquinoline-3-carboxylic acids

Journal of Medicinal Chemistry ◽

10.1021/jm00273a008 ◽

1972 ◽

Vol 15 (3) ◽

pp. 237-241 ◽

Cited By ~ 7

Author(s):

B. R. Baker ◽

Ray R. Bramhall

Keyword(s):

Carboxylic Acids ◽

Enzyme Inhibitors ◽

Hydrophobic Bonding

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Peptides: Synthesis, Structures, and Applications Edited by Bernd Gutte (Biochemisches Institut der Universit Zurich). Academic Press, San Diego, CA. 1995. xiv + 511 pp. 15 × 22.5 cm. $69.95. ISBN 0-12-310920-5.

Journal of Natural Products ◽

10.1021/np960471s ◽

1996 ◽

Vol 59 (12) ◽

pp. 1219-1220

Author(s):

Robert D. Walkup

Keyword(s):

San Diego ◽

Academic Press ◽

Peptides Synthesis

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3644 Pleiotropic effect of angiotensin-converting enzyme inhibitors on MMP-9: a key enzyme in cardiac and vascular remodelling

European Heart Journal ◽

10.1016/s0195-668x(03)96228-2 ◽

2003 ◽

Vol 24 (5) ◽

pp. 711

Author(s):

D REINHARDT

Keyword(s):

Angiotensin Converting Enzyme ◽

Enzyme Inhibitors ◽

Angiotensin Converting Enzyme Inhibitors ◽

Pleiotropic Effect ◽

Converting Enzyme ◽

Vascular Remodelling ◽

Converting Enzyme Inhibitors ◽

Key Enzyme

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