Mechanistical Insights into the Bioconjugation Reaction of Triazolinediones with Tyrosine

2018 ◽  
Vol 83 (17) ◽  
pp. 10248-10260 ◽  
Author(s):  
Dustin Kaiser ◽  
Johan M. Winne ◽  
Maria Elena Ortiz-Soto ◽  
Jürgen Seibel ◽  
Thien A. Le ◽  
...  
Keyword(s):  
Bioconjugation Reaction

In Situ IR Spectroscopic Studies of the Avidin−Biotin Bioconjugation Reaction on CdS Particle Films

Langmuir ◽  
2009 ◽  
Vol 25 (13) ◽  
pp. 7416-7423 ◽  
Author(s):  
Aidan G. Young ◽  
A.James McQuillan ◽  
David P. Green
Keyword(s):  
Spectroscopic Studies ◽  
In Situ Ir ◽  
Ir Spectroscopic ◽  
Bioconjugation Reaction

Wet Cross-Linking of Cellulose Fibers via a Bioconjugation Reaction

2011 ◽  
Vol 50 (10) ◽  
pp. 5907-5913 ◽  
Author(s):  
Alvaro Tejado ◽  
Miro Antal ◽  
Xiaojun Liu ◽  
Theo G. M. van de Ven
Keyword(s):  
Cellulose Fibers ◽  
Cross Linking ◽  
Bioconjugation Reaction

scholarly journals Continuous Flow Bioconjugations of NIR-AZA Fluorophores via Strained Alkyne Cycloadditions with Intra-chip Fluorogenic Monitoring

2021 ◽  
Author(s):  
Donal O'Shea ◽  
Sheila Fitzgerald
Keyword(s):  
Continuous Flow ◽  
Diels Alder ◽  
Reaction Monitoring ◽  
Dipolar Cycloadditions ◽  
Inverse Electron Demand ◽  
Specific Targeting ◽  
Novel Approach ◽  
Electron Demand ◽  
Chip Analysis ◽  
Bioconjugation Reaction

The importance of bioconjugation reactions continues to grow as the need for cell specific targeting and dual therapeutic plus diagnostic medical applications increase. This necessitates new bioconjugation chemistries, synthetic and analytical methods. With this goal, continuous flow bioconjugations were readily achieved with short residence times for strained alkyne substituted carbohydrate and peptide biomolecules in reaction with azide and tetrazine substituted fluorophores. The catalyst and reagent-free inverse electron demand tetrazine cycloadditions proved more favourable than the azide 1,3-dipolar cycloadditions. The use of a fluorogenic tetrazine fluorophore in a glass channelled reactor chip allowed for intra-chip reaction monitoring by recording fluorescence intensities at various positions throughout the chip. As the Diels-Alder reactions proceeded through the chip, the fluorescence intensity increased accordingly in real-time. This novel approach to continuous flow bioconjugation reaction with monitoring may offer advantages over post-chip analysis.

scholarly journals Electrochemical oxidation induced selective tyrosine bioconjugation for the modification of biomolecules

2019 ◽  
Vol 10 (34) ◽  
pp. 7982-7987 ◽  
Author(s):  
Chunlan Song ◽  
Kun Liu ◽  
Zhongjie Wang ◽  
Bo Ding ◽  
Shengchun Wang ◽  
...  
Keyword(s):  
Electrochemical Oxidation ◽  
Mild Conditions ◽  
Site Selectivity ◽  
Bioconjugation Reaction

This electrochemical bioconjugation reaction provides an efficient modification of biomolecules with high chemo- and site-selectivity under mild conditions.

Filamentous virus decoration with gold nanoparticles: global fingerprints of bionanocomposites acquired with SERS

RSC Advances ◽  
2014 ◽  
Vol 4 (100) ◽  
pp. 57329-57336 ◽  
Author(s):  
D. Montalvan-Sorrosa ◽  
J. L. González-Solis ◽  
J. Mas-Oliva ◽  
R. Castillo
Keyword(s):  
Gold Nanoparticles ◽  
Gold Nanoparticle ◽  
Gold Nanowire ◽  
Bioconjugation Reaction

A bioconjugation reaction is used to obtain fd viruses with one gold nanoparticle at the tip and gold nanowire-like structures.

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