Matched and Mismatched Phenomena in the Helix Orientation Bias Induced by Chiral Appendages at Multiple Positions of Indolocarbazole-Pyridine Hybrid Foldamers

2018 ◽  
Vol 83 (9) ◽  
pp. 5123-5131 ◽  
Author(s):  
Han Bit Jang ◽  
Ye Rin Choi ◽  
Kyu-Sung Jeong
Keyword(s):  
Helix Orientation ◽  
Orientation Bias

scholarly journals Influences of Histone Stoichiometry on the Target Site Preference of Retrotransposons Ty1 and Ty2 in Saccharomyces cerevisiae

Genetics ◽  
1996 ◽  
Vol 142 (3) ◽  
pp. 761-776 ◽  
Author(s):  
Lori A Rinckel ◽  
David J Garfinkel
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Promoter Region ◽  
Target Site ◽  
Site Preference ◽  
Wild Type ◽  
Histone Proteins ◽  
Protein Levels ◽  
In The Wild ◽  
Type Strains ◽  
Orientation Bias

Abstract In Saccharomyces cerevisiae, the target site specificity of the retrotransposon Ty1 appears to involve the Ty integration complex recognizing chromatin structures. To determine whether changes in chromatin structure affect Ty1 and Ty2 target site preference, we analyzed Ty transposition at the CAN1 locus in mutants containing altered levels of histone proteins. A Δhta1-htb1 mutant with decreased levels of H2A and H2B histone proteins showed a pattern of Ty1 and Ty2 insertions at CAN1 that was significantly different from that of both the wild-type and a Δhta2-htb2 mutant, which does not have altered histone protein levels. Altered levels of H2A and H2B proteins disrupted a dramatic orientation bias in the CAN1 promoter region. In the wild-type strains, few Ty1 and Ty2 insertions in the promoter region were oriented opposite to the direction of CAN1 transcription. In the Δhta1-htb1 background, however, numerous Ty1 and Ty2 insertions were in the opposite orientation clustered within the TATA region. This altered insertion pattern does not appear to be due to a bias caused by selecting canavanine resistant isolates in the different HTA1-HTB1 backgrounds. Our results suggest that reduced levels of histone proteins alter Ty target site preference and disrupt an asymmetric Ty insertion pattern.

The orientation bias of Chi sequences is a general tendency of G-rich oligomers

Gene ◽  
2000 ◽  
Vol 259 (1-2) ◽  
pp. 207-215 ◽  
Author(s):  
Reina Uno ◽  
Yoichi Nakayama ◽  
Kazuharu Arakawa ◽  
Masaru Tomita
Keyword(s):  
General Tendency ◽  
Orientation Bias

Coming Out in Class: Disclosure of Sexual Orientation and Teaching Evaluations

1997 ◽  
Vol 24 (1) ◽  
pp. 32-35 ◽  
Author(s):  
Becky J. Liddle
Keyword(s):  
Sexual Orientation ◽  
Coming Out ◽  
Counseling Psychology ◽  
Assistant Professor ◽  
Group Differences ◽  
Teaching Evaluations ◽  
Disclosure Of Sexual Orientation ◽  
Orientation Bias

A lesbian assistant professor of counseling psychology disclosed her sexual orientation during lectures to 2 sections of an undergraduate course and did not disclose in 2 comparable sections of the same course. Group differences in means and variances of teaching evaluations were examined for possible student bias. No evidence of sexual orientation bias was found.

scholarly journals Analysis of orientation bias in cat retina

1982 ◽  
Vol 329 (1) ◽  
pp. 243-261 ◽  
Author(s):  
W. R. Levick ◽  
L. N. Thibos
Keyword(s):  
Cat Retina ◽  
Orientation Bias

scholarly journals Fast-spiking interneurons have an initial orientation bias that is lost with vision

2011 ◽  
Vol 14 (9) ◽  
pp. 1121-1123 ◽  
Author(s):  
Sandra J Kuhlman ◽  
Elaine Tring ◽  
Joshua T Trachtenberg
Keyword(s):  
Initial Orientation ◽  
Fast Spiking ◽  
Orientation Bias

scholarly journals A Truncation Mutant of the 95-Kilodalton Subunit of Transcription Factor IIIC Reveals Asymmetry in Ty3 Integration

2001 ◽  
Vol 21 (22) ◽  
pp. 7839-7851 ◽  
Author(s):  
Michael Aye ◽  
Sandra L. Dildine ◽  
Jonathan A. Claypool ◽  
Sabine Jourdain ◽  
Suzanne B. Sandmeyer
Keyword(s):  
Transcription Initiation ◽  
Protein Complexes ◽  
Proteolytic Processing ◽  
Trna Genes ◽  
Wild Type ◽  
Long Terminal Repeats ◽  
Truncation Mutant ◽  
Two Hybrid ◽  
Orientation Bias

ABSTRACT Position-specific integration of the retroviruslike element Ty3 near the transcription initiation sites of tRNA genes requires transcription factors IIIB and IIIC (TFIIIB and TFIIIC). Using a genetic screen, we isolated a mutant with a truncated 95-kDa subunit of TFIIIC (TFIIIC95) that reduced the apparent retrotransposition of Ty3 into a plasmid-borne target site between two divergently transcribed tRNA genes. Although TFIIIC95 is conserved and essential, no defect in growth or transcription of tRNAs was detected in the mutant. Steps of the Ty3 life cycle, such as protein expression, proteolytic processing, viruslike particle formation, and reverse transcription, were not affected by the mutation. However, Ty3 integration into a divergent tDNA target occurred exclusively in one orientation in the mutant strain. Investigation of this orientation bias showed that TFIIIC95 and Ty3 integrase interacted in two-hybrid and glutathioneS-transferase pulldown assays and that interaction with the mutant TFIIIC95 protein was attenuated. The orientation bias observed here suggests that even for wild-type Ty3, the protein complexes associated with the long terminal repeats are not equivalent in vivo.

Induction Motor Vector Control Based on Adaptive Identification of Rotor Parameters

2014 ◽  
Vol 494-495 ◽  
pp. 1517-1523
Author(s):  
Qi Wei Xu ◽  
Jia Ning Xu
Keyword(s):  
Control System ◽  
Vector Control ◽  
Induction Motor ◽  
Design Method ◽  
Theory And Practice ◽  
Adaptive Identification ◽  
Lyapunov Stabilization ◽  
Simulation Results ◽  
Vector Control System ◽  
Orientation Bias

The paper analyzed the influence of rotor parameters changing for the induction motor vector control, and an adaptive identification method for rotor parameters was proposed. Based on Lyapunov stabilization theory, design method of adaptive identification discipline was expatiated. The model of rotor parameters adaptive identification under induction motor vector control was completed using Matlab/Simulink. The simulation results demonstrate the feasibility of the proposed method, and it can be taken as the theory and practice reference for improve the orientation bias for vector control system.

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