Synthesis of 4-Acylpyrazoles from Saturated Ketones and Hydrazones Featured with Multiple C(sp3)–H Bond Functionalization and C–C Bond Cleavage and Reorganization

2017 ◽  
Vol 82 (14) ◽  
pp. 7363-7372 ◽  
Author(s):  
Miaomiao Tian ◽  
Xiaonan Shi ◽  
Xinying Zhang ◽  
Xuesen Fan
Keyword(s):  
Bond Cleavage ◽  
Bond Functionalization

The Mechanism of NO Bond Cleavage in Rhodium-Catalyzed CH Bond Functionalization of QuinolineN-oxides with Alkynes: A Computational Study

2015 ◽  
Vol 21 (28) ◽  
pp. 10131-10137 ◽  
Author(s):  
Yingzi Li ◽  
Song Liu ◽  
Zisong Qi ◽  
Xiaotian Qi ◽  
Xingwei Li ◽  
...  
Keyword(s):  
Computational Study ◽  
Bond Cleavage ◽  
Bond Functionalization

Direct C–H heteroarylation of azoles with 1,2-di(pyrimidin-2-yl)disulfides through C–S cleavage of disulfides

RSC Advances ◽  
2016 ◽  
Vol 6 (81) ◽  
pp. 78059-78063 ◽  
Author(s):  
Kai-Jie Wei ◽  
Zheng-jun Quan ◽  
Zhang Zhang ◽  
Yu-xia Da ◽  
Xi-cun Wang
Keyword(s):  
Bond Cleavage ◽  
Bond Functionalization

C–C bond construction via C–H bond functionalization of oxazoles/thiazoles and C–S bond cleavage of di(hetero)aryl disulfides are described.

Advances in Silylation and Borylation of Fluoroarenes and gem-Difluoroalkenes via C-F bond Cleavage

2021 ◽  
Author(s):  
Zhang Feng ◽  
Shasha Geng ◽  
Juan Zhang
Keyword(s):  
Organic Synthesis ◽  
Bond Cleavage ◽  
Bond Functionalization

Organoboron and organosilane compounds are widely used in organic synthesis and pharmaceuticals. In addition, the C-F bond functionalization is a useful tool for the construction of carbon-carbon and carbon-heteroatom bonds....

Visible Light Promotes Decyanation Esterification Reaction of β-Ketonitriles with Dioxygen and Alcohols to α-Ketoesters

Synlett ◽  
2018 ◽  
Vol 29 (08) ◽  
pp. 1065-1070 ◽  
Author(s):  
Cheng Guo ◽  
Chen Xu ◽  
Nan-Nan Zhang ◽  
Xiao-ji Li ◽  
Yan-qin Ge ◽  
...  
Keyword(s):  
Visible Light ◽  
Singlet Oxygen ◽  
Bond Cleavage ◽  
Esterification Reaction ◽  
Bond Functionalization ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Catalyst Free ◽  
Plausible Mechanism

A green and mild method has been developed for the conversion of β-ketonitriles into α-ketoesters under catalyst-free conditions. A plausible mechanism is that visible light promotes singlet oxygen generation to form the products through oxidative C–H bond functionalization and C–C σ-bond cleavage.

C(sp3)–H Bond Functionalization of Benzo[c]oxepines via C–O bond Cleavage: Formal [3+3] Synthesis of Multisubstituted Chromans

2018 ◽  
Vol 83 (6) ◽  
pp. 3409-3416 ◽  
Author(s):  
Miao Wang ◽  
Bo-Cheng Tang ◽  
Jia-Chen Xiang ◽  
Yan Cheng ◽  
Zi-Xuan Wang ◽  
...  
Keyword(s):  
Bond Cleavage ◽  
Bond Functionalization

From Simple to Complex: Rhodium(III)-Catalyzed C–C Bond Cleavage and C–H Bond Functionalization for the Synthesis of 3a,8b-Dihydro-1H-cyclopenta[b]benzofuran-1-ones

2017 ◽  
Vol 19 (19) ◽  
pp. 5026-5029 ◽  
Author(s):  
Guiyu Guo ◽  
Saihong Wan ◽  
Xiaodong Si ◽  
Qijian Jiang ◽  
Yuanyuan Jia ◽  
...  
Keyword(s):  
Bond Cleavage ◽  
Bond Functionalization

Amidinyl Radical Formation through Anodic N−H Bond Cleavage and Its Application in Aromatic C−H Bond Functionalization

2016 ◽  
Vol 129 (2) ◽  
pp. 602-605 ◽  
Author(s):  
Huai-Bo Zhao ◽  
Zhong-Wei Hou ◽  
Zhan-Jiang Liu ◽  
Ze-Feng Zhou ◽  
Jinshuai Song ◽  
...  
Keyword(s):  
Bond Cleavage ◽  
Radical Formation ◽  
Bond Functionalization

Amidinyl Radical Formation through Anodic N−H Bond Cleavage and Its Application in Aromatic C−H Bond Functionalization

2016 ◽  
Vol 56 (2) ◽  
pp. 587-590 ◽  
Author(s):  
Huai-Bo Zhao ◽  
Zhong-Wei Hou ◽  
Zhan-Jiang Liu ◽  
Ze-Feng Zhou ◽  
Jinshuai Song ◽  
...  
Keyword(s):  
Bond Cleavage ◽  
Radical Formation ◽  
Bond Functionalization

scholarly journals Recent Advances in C–H Bond Functionalization with Ruthenium-Based Catalysts

Catalysts ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 173 ◽  
Author(s):  
Keisham Singh
Keyword(s):  
Transition Metals ◽  
Bond Cleavage ◽  
Rapid Development ◽  
Bond Functionalization ◽  
Bond Forming ◽  
The Past ◽  
Tremendous Progress ◽  
Specific Manner ◽  
Ruthenium Catalysis ◽  
Cleavage Reactions

The past decades have witnessed rapid development in organic synthesis via catalysis, particularly the reactions through C–H bond functionalization. Transition metals such as Pd, Rh and Ru constitute a crucial catalyst in these C–H bond functionalization reactions. This process is highly attractive not only because it saves reaction time and reduces waste,but also, more importantly, it allows the reaction to be performed in a highly region specific manner. Indeed, several organic compounds could be readily accessed via C–H bond functionalization with transition metals. In the recent past, tremendous progress has been made on C–H bond functionalization via ruthenium catalysis, including less expensive but more stable ruthenium(II) catalysts. The ruthenium-catalysed C–H bond functionalization, viz. arylation, alkenylation, annulation, oxygenation, and halogenation involving C–C, C–O, C–N, and C–X bond forming reactions, has been described and presented in numerous reviews. This review discusses the recent development of C–H bond functionalization with various ruthenium-based catalysts. The first section of the review presents arylation reactions covering arylation directed by N–Heteroaryl groups, oxidative arylation, dehydrative arylation and arylation involving decarboxylative and sp3-C–H bond functionalization. Subsequently, the ruthenium-catalysed alkenylation, alkylation, allylation including oxidative alkenylation and meta-selective C–H bond alkylation has been presented. Finally, the oxidative annulation of various arenes with alkynes involving C–H/O–H or C–H/N–H bond cleavage reactions has been discussed.

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