Readily Accessible 1,2-Amino Ether Ligands for Enantioselective Intramolecular Carbolithiation

2017 ◽  
Vol 82 (9) ◽  
pp. 4949-4957 ◽  
Author(s):  
Hélène Guyon ◽  
Anne Boussonnière ◽  
Anne-Sophie Castanet
Keyword(s):  
Amino Ether

Amino-ether macrocycle that forms CuII templated threaded heteroleptic complexes: a detailed selectivity, structural and theoretical investigations

2015 ◽  
Vol 44 (34) ◽  
pp. 15198-15211 ◽  
Author(s):  
Saikat Santra ◽  
Sandip Mukherjee ◽  
Somnath Bej ◽  
Subrata Saha ◽  
Pradyut Ghosh
Keyword(s):  
Metal Ions ◽  
Divalent Metal ◽  
Divalent Metal Ions ◽  
Heteroleptic Complexes ◽  
Theoretical Investigations ◽  
Amino Ether

Self-sorting behavior of a newly synthesized macrocycle with divalent metal ions and aromatic ligands via pseudorotaxane formation has been described.

Synthesis of several 4-hydroxy-3,5-dimethoxybenzamides, their O-substituted derivatives and some related compounds as potential neurotropic agents

1985 ◽  
Vol 50 (2) ◽  
pp. 510-518 ◽  
Author(s):  
Vladimír Valenta ◽  
Miroslav Protiva
Keyword(s):  
Blood Pressure ◽  
Catalytic Hydrogenation ◽  
Anticonvulsant Activity ◽  
Sodium Hydride ◽  
Antiemetic Agent ◽  
Related Compounds ◽  
Neurotropic Agents ◽  
Amino Ether

Reactions of 4-benzyloxy-3,5-dimethoxybenzoyl chloride with pyrrolidine, piperidine, morpholine and 1-methylpiperazine gave the amides IIIa-IIId which were debenzylated by catalytic hydrogenation on palladium. The 4-hydroxy-3,5-dimethoxybenzamides IVa-IVc were then treated with sodium hydride and 2-dimethylaminoethyl chloride to give the O-(2-dimethylaminoethyl)amides Va-Vc. The 3,4,5-trimethoxybenzamide IX was prepared as a homologue of the antiemetic agent "trimethobenzamide" (II) and reduced to the benzylaniline derivative X. The substituted nicotinamide XI was obtained from nicotinoyl chloride and 4-(2-diethylaminoethoxy)aniline. Out of the compounds prepared the amides IIId and Vc had some anticonvulsant activity, the piperazide IVd revealed a significant α-adrenolytic effect and the amino ether X reduced the blood pressure of normotensive rats.

ChemInform Abstract: Straightforward Synthesis of 1,2-Amino Phosphate Diesters and Application to the Synthesis of Novel 1,2-Amino Ether Diesters.

ChemInform ◽  
2010 ◽  
Vol 41 (25) ◽  
pp. no-no
Author(s):  
Brahim Ould Elemine ◽  
Rafaa Besbes ◽  
Mohamed Rached Ennigrou
Keyword(s):  
Phosphate Diesters ◽  
Amino Ether

Straightforward Synthesis of 1,2-Amino Phosphate Diesters and Application to the Synthesis of Novel 1,2-Amino Ether Diesters

2009 ◽  
Vol 40 (1) ◽  
pp. 64-73 ◽  
Author(s):  
Brahim Ould Elemine ◽  
Rafâa Besbes ◽  
Mohamed Rached Ennigrou
Keyword(s):  
Phosphate Diesters ◽  
Amino Ether
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