Metal-Free Intermolecular Coupling of Arenes with Secondary Amides: Chemoselective Synthesis of Aromatic Ketimines and Ketones, and N-Deacylation of Secondary Amides

2016 ◽  
Vol 81 (19) ◽  
pp. 9020-9027 ◽  
Author(s):  
Pei-Qiang Huang ◽  
Ying-Hong Huang ◽  
Kai-Jiong Xiao
Keyword(s):  
Metal Free ◽  
Chemoselective Synthesis ◽  
Secondary Amides ◽  
Intermolecular Coupling

Metal-Free [2 + 2 + 2] Cycloaddition of Ynamide–Nitriles with Ynamides: A Highly Regio- and Chemoselective Synthesis of δ-Carboline Derivatives

2018 ◽  
Vol 83 (21) ◽  
pp. 13308-13324 ◽  
Author(s):  
Hao Wen ◽  
Wei Cao ◽  
Yu Liu ◽  
Liang Wang ◽  
Ping Chen ◽  
...  
Keyword(s):  
Metal Free ◽  
Chemoselective Synthesis

Phosphazene-Promoted Metal-Free Ring-Opening Polymerization of 1,2-Epoxybutane Initiated by Secondary Amides

2015 ◽  
Vol 48 (21) ◽  
pp. 7755-7764 ◽  
Author(s):  
Laetitia Dentzer ◽  
Caroline Bray ◽  
Sylvie Noinville ◽  
Nicolas Illy ◽  
Philippe Guégan
Keyword(s):  
Ring Opening ◽  
Ring Opening Polymerization ◽  
Free Ring ◽  
Metal Free ◽  
Secondary Amides

ChemInform Abstract: Mild Metal-Free Hydrosilylation of Secondary Amides to Amines.

ChemInform ◽  
2016 ◽  
Vol 47 (40) ◽  
Author(s):  
Pei-Qiang Huang ◽  
Qi-Wei Lang ◽  
Yan-Rong Wang
Keyword(s):  
Metal Free ◽  
Secondary Amides

Tf2 O-Mediated Intermolecular Coupling of Secondary Amides with Enamines or Ketones: A Versatile and Direct Access to β-Enaminones

2019 ◽  
Vol 2019 (42) ◽  
pp. 7169-7174 ◽  
Author(s):  
Yong-Peng Liu ◽  
Cheng-Jie Zhu ◽  
Cun-Cun Yu ◽  
Ai-E Wang ◽  
Pei-Qiang Huang
Keyword(s):  
Direct Access ◽  
Secondary Amides ◽  
Intermolecular Coupling

ChemInform Abstract: Metal-Free N-Arylation of Secondary Amides at Room Temperature.

ChemInform ◽  
2015 ◽  
Vol 46 (41) ◽  
pp. no-no
Author(s):  
Fredrik Tinnis ◽  
Elin Stridfeldt ◽  
Helena Lundberg ◽  
Hans Adolfsson ◽  
Berit Olofsson
Keyword(s):  
Room Temperature ◽  
Metal Free ◽  
Secondary Amides

ChemInform Abstract: Metal-Free One-Pot Domino Reaction: Chemoselective Synthesis of Polyarylated Oxazoles.

ChemInform ◽  
2015 ◽  
Vol 46 (37) ◽  
pp. no-no
Author(s):  
Hua Meng ◽  
You Zi ◽  
Xiao-Ping Xu ◽  
Shun-Jun Ji
Keyword(s):  
Domino Reaction ◽  
One Pot ◽  
Metal Free ◽  
Chemoselective Synthesis

Transition metal-free N-arylation of secondary amides through iodonium salts as aryne precursors

2016 ◽  
Vol 14 (43) ◽  
pp. 10185-10188 ◽  
Author(s):  
Ming Wang ◽  
Zhijian Huang
Keyword(s):  
Transition Metal ◽  
Iodonium Salts ◽  
Metal Free ◽  
Diaryliodonium Salts ◽  
Secondary Amides

A transition metal-free approach for N-arylation of secondary amides was developed via diaryliodonium salts as aryne precursors.

scholarly journals Catalyst-Free, Metal-Free, and Chemoselective Transamidation of Activated Secondary Amides

Synthesis ◽  
2018 ◽  
Vol 51 (04) ◽  
pp. 921-932 ◽  
Author(s):  
Srinivasan Chandrasekaran ◽  
Rajagopal Ramkumar
Keyword(s):  
Amino Acids ◽  
The Other ◽  
Metal Free ◽  
Mild Conditions ◽  
Catalyst Free ◽  
Wide Range ◽  
Simple Protocol ◽  
Secondary Amides ◽  
Free Metal ◽  
Better Than

A simple protocol, which is catalyst-free, metal-free, and chemoselective, for transamidation of activated secondary amides in ethanol as solvent under mild conditions is reported. A wide range of amines, amino acids, amino alcohols, and the substituents, which are problematic in catalyzed transamidation, are tolerated in this methodology. The transamidation reaction was successfully extended to water as the medium as well. The present methodology appears to be better than the other catalyzed transamidations reported recently.

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