Synthesis of Tetracyclic Quinazolinones Using a Visible-Light-Promoted Radical Cascade Approach

2016 ◽  
Vol 81 (16) ◽  
pp. 7276-7281 ◽  
Author(s):  
Yue-Yue Han ◽  
Heng Jiang ◽  
Ruzhi Wang ◽  
Shouyun Yu
Keyword(s):  
Visible Light ◽  
Radical Cascade

Eosin Y photoredox catalyzed net redox neutral reaction for regiospecific annulation to 3-sulfonylindoles via anion oxidation of sodium sulfinate salts

2018 ◽  
Vol 16 (4) ◽  
pp. 536-540 ◽  
Author(s):  
Rajendra S. Rohokale ◽  
Shrikant D. Tambe ◽  
Umesh A. Kshirsagar
Keyword(s):  
Visible Light ◽  
Eosin Y ◽  
Cascade Cyclization ◽  
Neutral Reaction ◽  
Neutral Process ◽  
Radical Cascade

An eosin Y photoredox catalyzed net redox neutral process for 3-sulfonylindoles via the anionic oxidation of sodium sulfinate salts and its radical cascade cyclization with 2-alkynyl-azidoarenes was developed with visible light as a mediator.

Organic Photocatalytic Cyclization of Polyenes: A Visible-Light-Mediated Radical Cascade Approach

2015 ◽  
Vol 21 (42) ◽  
pp. 14723-14727 ◽  
Author(s):  
Zhongbo Yang ◽  
Han Li ◽  
Long Zhang ◽  
Ming-Tian Zhang ◽  
Jin-Pei Cheng ◽  
...  
Keyword(s):  
Visible Light ◽  
Radical Cascade

Visible-light-induced intramolecular radical cascade of α-bromo-N-benzyl-alkylamides: a new strategy to synthesize tetracyclic N-fused indolo[2,1-a]isoquinolin-6(5H)-ones

2020 ◽  
Vol 18 (2) ◽  
pp. 263-271 ◽  
Author(s):  
Xiaoshuang Gao ◽  
Chengyang Li ◽  
Yao Yuan ◽  
Xiaomin Xie ◽  
Zhaoguo Zhang
Keyword(s):  
Natural Products ◽  
Visible Light ◽  
Materials Science ◽  
New Strategy ◽  
Radical Cascade

Polycyclic indole scaffolds are ubiquitous in pharmaceuticals and natural products and in materials science.

Visible-light-mediated radical cascade reaction: synthesis of 3-bromocoumarins from alkynoates

2017 ◽  
Vol 15 (41) ◽  
pp. 8820-8826 ◽  
Author(s):  
Shangbiao Feng ◽  
Jinlai Li ◽  
Zaimin Liu ◽  
Haiyu Sun ◽  
Hongliang Shi ◽  
...  
Keyword(s):  
Visible Light ◽  
Cascade Reaction ◽  
Radical Addition ◽  
Reaction Synthesis ◽  
Radical Cascade

The development of a visible-light mediated bromo radical addition/spirocyclization/ester migration cascade reaction to generate 3-bromocoumarins from alkynoates is reported.

Visible-Light-Induced Radical Cascade Cyclization: Synthesis of (20S )-Camptothecin, SN-38 and Irinotecan

2018 ◽  
Vol 36 (11) ◽  
pp. 1035-1040 ◽  
Author(s):  
Yao Yuan ◽  
Wuheng Dong ◽  
Xiaoshuang Gao ◽  
Xiaomin Xie ◽  
Dennis P. Curran ◽  
...  
Keyword(s):  
Visible Light ◽  
Cascade Cyclization ◽  
Radical Cascade

scholarly journals Asymmetric Total Synthesis of (+)-21-epi-Eburnamonine Via a Photocatalytic Radical Cascade Reaction

2020 ◽  
Author(s):  
Yuan Huang ◽  
Fanglin Xue ◽  
Hengmao Liu ◽  
Fei Xue ◽  
Xiao-Yu Liu ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Visible Light ◽  
Claisen Rearrangement ◽  
Cascade Reaction ◽  
Ring System ◽  
Asymmetric Total Synthesis ◽  
Radical Cascade ◽  
Key Features ◽  
Quaternary Stereocenter ◽  
Visible Light Photocatalytic

Abstract An asymmetric total synthesis of (+)-21-epi-eburnamonine has been achieved. Key features of the synthesis include a visible-light photocatalytic intra-/intramolecular radical cascade reaction to assemble the tetracyclic ABCD ring system, and a highly diastereoselective Johnson-Claisen rearrangement to establish the C20 all-carbon quaternary stereocenter. Graphic Abstract

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