Achyrophenols A–F: Polycyclic Polyphenol Lactone Skeletons and a Nor-Ursane-Type Triterpenoid from Achyrocline Satureioides

Author(s):  
Shicheng Wang ◽  
Dongming Zhang ◽  
Jinhua Zhu ◽  
Hongdong Liu ◽  
Bin Li ◽  
...  
1998 ◽  
Vol 24 (3) ◽  
pp. 235-241 ◽  
Author(s):  
I. C. de Paula ◽  
G. González Ortega ◽  
V. L. Bassani ◽  
P. R. Petrovick

2004 ◽  
Vol 91 (1) ◽  
pp. 13-20 ◽  
Author(s):  
M.F Arredondo ◽  
F Blasina ◽  
C Echeverry ◽  
A Morquio ◽  
M Ferreira ◽  
...  

2017 ◽  
Vol 37 ◽  
pp. 368-374 ◽  
Author(s):  
Ketheley L. Guss ◽  
Stefano Pavanni ◽  
Bruno Prati ◽  
Lucas Dazzi ◽  
Jairo P. de Oliveira ◽  
...  

2018 ◽  
Vol 8 ◽  
Author(s):  
Nathalia Stark Pedra ◽  
Kennia de Cássia Araújo Galdino ◽  
Daniel Schuch da Silva ◽  
Priscila Treptow Ramos ◽  
Natália Pontes Bona ◽  
...  

2001 ◽  
Vol 31 (3) ◽  
pp. 517-518 ◽  
Author(s):  
Flávia Charão Marques ◽  
Ingrid Bergman Inchausti de Barros

Avaliaram-se o estabelecimento e crescimento inicial de plantas de marcela e a viabilidade da produção de mudas a partir de sementes. O estudo foi conduzido em casa de vegetação. A semeadura foi feita a lanço sobre um substrato 1:1:1 de turfa, casca de arroz carbonizada e composto orgânico, em bandejas de alumínio. O delineamento experimental foi completamente casualizado, com 10 repetições. Determinou-se a massa fresca e seca de 10 plantas por repetição a cada 10 dias, até os 70 dias após a semeadura. A germinação das sementes foi desuniforme e o ganho de massa fresca e seca indicou que o crescimento inicial foi lento; havendo maior incremento a partir dos 50 dias da semeadura. O estabelecimento das plantas foi satisfatório e a obtenção de mudas através de sementes foi viável.


Pharmaceutics ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1241
Author(s):  
Lucélia Albarello Balestrin ◽  
Tainá Kreutz ◽  
Flávia Nathiely Silveira Fachel ◽  
Juliana Bidone ◽  
Nicolly Espindola Gelsleichter ◽  
...  

Achyrocline satureioides (Lam.) DC Asteraceae extracts (ASEs) have been investigated for the treatment of various skin disorders. This study reports the effects of ASE-loaded nanoemulsions (NEASE) on the cellular viability, death by necrosis, and migration of immortalized human keratinocytes (HaCaT cell line), as well as the irritant potential through the hen’s egg chorioallantoic membrane test (HET-CAM). NEASE exhibited a polydispersity index above 0.12, with a droplet size of 300 nm, ζ-potential of −40 mV, and content of flavonoids close to 1 mg/mL. No cytotoxicity of the ASE was observed on HaCaT by MTT assay (up to 10 µg/mL). A significant increase of HaCaT viability was observed to NEASE (up to 5 μg/mL of flavonoids), compared to treatment with the ASE. The necrosis death evaluation demonstrated that only NEASE did not lead to cell death at all the tested concentrations. The scratch assay demonstrated that NEASE was able to increase the cell migration at low flavonoid concentrations. Finally, the HET-CAM test proved the non-irritative potential of NEASE. Overall, the results indicate the potential of the proposed formulations for topical use in wound healing, in view of their promising effects on proliferation and migration in keratinocytes, combined with an indication of the absence of cytotoxicity and non-irritating potential.


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