Total Synthesis, Structure Revision, and Neuroprotective Effect of Hericenones C–H and Their Derivatives

2021 ◽  
Vol 86 (3) ◽  
pp. 2602-2620
Author(s):  
Shoji Kobayashi ◽  
Tomoki Tamura ◽  
Mizuho Koshishiba ◽  
Takeshi Yasumoto ◽  
Satoshi Shimizu ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Neuroprotective Effect ◽  
Structure Revision

scholarly journals Total Synthesis of the Alleged Structure of Crenarchaeol enables Structure Revision

2021 ◽  
Author(s):  
Mira Holzheimer ◽  
Jaap S. Sinninghe Damsté ◽  
Stefan Schouten ◽  
Remco W. A. Havenith ◽  
Ana V. Cunha ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Structure Revision

Bioinspired Total Synthesis of Marine Anti-Cancer Meroterpenoids Dysideanone B and Dysiherbol A and Structure Revision of Dysiherbol A

Synlett ◽  
2021 ◽  
Author(s):  
Zhaoyong Lu ◽  
Chuanke Chong
Keyword(s):  
Total Synthesis ◽  
Heck Reaction ◽  
Recent Progress ◽  
Benzyl Bromide ◽  
Radical Cyclization ◽  
Ethoxy Group ◽  
Anti Cancer ◽  
Structure Revision ◽  
A Site ◽  
Intramolecular Heck Reaction

Our recent progress on the total synthesis of marine anti-cancer sesquiterpene quinone/hydroquinone dysideanone B and dysiherbol A was briefly highlighted. This success relied on some key transformations. The union of the terpene and quinone/hydroquinone moieties was realized through a site and stereoselective α-position alkylation of Wieland–Miescher ketone derivative with a bulky benzyl bromide. The 6/6/6/6-tetracycle of dysideanone B was constructed using an intramolecular radical cyclization and the 6/6/5/6-fused core structure of dysiherbol A was forged by an intramolecular Heck reaction, respectively. The possible origin of ethoxy group in dysideanone B was revealed by mimicking the isolation conditions at a late-stage. The structure of dysiherbol A was revised through the total synthesis of this natural product. Schmalz’s synthesis of dysiherbol A was also included.

Total Synthesis and Structure Revision of (−)-Avicennone C

2020 ◽  
Vol 85 (20) ◽  
pp. 13108-13120
Author(s):  
Yolanda Kleiner ◽  
Peter Hammann ◽  
Jonathan Becker ◽  
Armin Bauer ◽  
Christoph Pöverlein ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Structure Revision

ChemInform Abstract: Total Synthesis and Structure Revision of Mirubactin, and Its Iron Binding Activity.

ChemInform ◽  
2016 ◽  
Vol 47 (16) ◽  
Author(s):  
Shinji Kishimoto ◽  
Shinichi Nishimura ◽  
Hideaki Kakeya
Keyword(s):  
Total Synthesis ◽  
Binding Activity ◽  
Iron Binding ◽  
Structure Revision

Substrate-Controlled Asymmetric Total Synthesis and Structure Revision of (+)-Itomanallene A

2009 ◽  
Vol 122 (4) ◽  
pp. 764-768 ◽  
Author(s):  
Wonjang Jeong ◽  
Mi Jung Kim ◽  
Hyoungsu Kim ◽  
Sanghee Kim ◽  
Deukjoon Kim ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Asymmetric Total Synthesis ◽  
Structure Revision

Total synthesis and neuroprotective effect of O-methylmurrayamine A and 7-methoxymurrayacine

2017 ◽  
Vol 19 (6) ◽  
pp. 623-629 ◽  
Author(s):  
Ying-Da Zang ◽  
Chuang-Jun Li ◽  
Xiu-Yun Song ◽  
Jie Ma ◽  
Jing-Zhi Yang ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Neuroprotective Effect

Total Synthesis and Structure Revision ofStachybotrysSpirolactams

2003 ◽  
Vol 68 (19) ◽  
pp. 7422-7427 ◽  
Author(s):  
Wei-Ping Deng ◽  
Min Zhong ◽  
Xiao-Chuan Guo ◽  
Andrew S. Kende
Keyword(s):  
Total Synthesis ◽  
Structure Revision

A Total Synthesis Prompts the Structure Revision of Haouamine B

2012 ◽  
Vol 134 (22) ◽  
pp. 9291-9295 ◽  
Author(s):  
Maria Matveenko ◽  
Guangxin Liang ◽  
Erica M. W. Lauterwasser ◽  
Eva Zubía ◽  
Dirk Trauner
Keyword(s):  
Total Synthesis ◽  
Structure Revision
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