Cyanide Ion-Promoted Nucleophilic Displacement of Aromatic Nitro Groups: A Mild, One-Pot, Transition Metal-Free Synthesis of Nitrile-Containing Naphthalimide Aryl Ether Derivatives

2021 ◽  
Vol 86 (3) ◽  
pp. 3059-3064
Author(s):  
Lu Chen ◽  
Xi Chen ◽  
Tingting Zhu ◽  
Haibing Shao ◽  
Zhihua Chen ◽  
...  
Keyword(s):  
Transition Metal ◽  
Aryl Ether ◽  
Cyanide Ion ◽  
One Pot ◽  
Metal Free ◽  
Nucleophilic Displacement ◽  
Aromatic Nitro

scholarly journals An entry to 2-(cyclobut-1-en-1-yl)-1H-indoles through a cyclobutenylation/deprotection cascade

2021 ◽  
Author(s):  
Philipp Natho ◽  
Zeyu Yang ◽  
Lewis Allen ◽  
Juliette Rey ◽  
Andrew J P White ◽  
...  
Keyword(s):  
Transition Metal ◽  
One Pot ◽  
Metal Free ◽  
Mild Conditions

A transition-metal-free strategy for the synthesis of 2-(cyclobut-1-en-1-yl)-1H-indoles under mild conditions is described herein. A series of substituted 2-(cyclobut-1-en-1-yl)-1H-indoles are accessed by a one-pot cyclobutenylation/deprotection cascade from N-Boc protected indoles....

ChemInform Abstract: Transition Metal Free Intramolecular S-Arylation: One-Pot Synthesis of Thiochromen-4-ones.

ChemInform ◽  
2014 ◽  
Vol 45 (13) ◽  
pp. no-no
Author(s):  
T. A. Jenifer Vijay ◽  
Kebbahalli N. Nandeesh ◽  
Goravanahalli M. Raghavendra ◽  
Kanchugarakoppal S. Rangappa ◽  
Kempegowda Mantelingu
Keyword(s):  
Transition Metal ◽  
One Pot ◽  
Metal Free ◽  
One Pot Synthesis

ChemInform Abstract: A One-Pot Transition Metal Free Tandem Process to 1,4-Benzodiazepine Scaffolds.

ChemInform ◽  
2013 ◽  
Vol 44 (17) ◽  
pp. no-no
Author(s):  
Yanqiu Li ◽  
Chunjing Zhan ◽  
Bingchuan Yang ◽  
Xiaoqun Cao ◽  
Chen Ma
Keyword(s):  
Transition Metal ◽  
One Pot ◽  
Metal Free ◽  
Tandem Process

One-pot synthesis of thioesters with sodium thiosulfate as a sulfur surrogate under transition metal-free conditions

2018 ◽  
Vol 16 (11) ◽  
pp. 1871-1881 ◽  
Author(s):  
Yen-Sen Liao ◽  
Chien-Fu Liang
Keyword(s):  
Transition Metal ◽  
Sodium Thiosulfate ◽  
Sulfur Source ◽  
One Pot ◽  
Metal Free ◽  
One Pot Synthesis

We have developed a one-pot reaction to provide thioester derivativesviasodium thiosulfate as a sulfur source under transition metal-free conditions.

One-pot transition-metal free transamidation to sterically hindered amides

2018 ◽  
Vol 5 (20) ◽  
pp. 2950-2954 ◽  
Author(s):  
Weijie Guo ◽  
Jingjun Huang ◽  
Hongxiang Wu ◽  
Tingting Liu ◽  
Zhongfeng Luo ◽  
...  
Keyword(s):  
Transition Metal ◽  
Good Yield ◽  
One Pot ◽  
Metal Free ◽  
Highly Efficient ◽  
Sterically Hindered

A highly efficient one-pot transamidation of primary amides has been developed under transition-metal free conditions, generating a variety of amides including hindered amides in good yield (up to 86%) catalyzed by CsF.

scholarly journals SO2F2-Mediated one-pot cascade process for transformation of aldehydes (RCHO) to cyanamides (RNHCN)

RSC Advances ◽  
2020 ◽  
Vol 10 (29) ◽  
pp. 17288-17292 ◽  
Author(s):  
Yiyong Zhao ◽  
Junjie Wei ◽  
Shuting Ge ◽  
Guofu Zhang ◽  
Chengrong Ding
Keyword(s):  
Transition Metal ◽  
Nitrogen Source ◽  
Functional Group ◽  
Cascade Process ◽  
One Pot ◽  
Metal Free ◽  
Work Up

Our gram-scale process uses abundant and inexpensive aldehydes, a clean nitrogen source, requires no additional carbon atoms, is transition-metal free, and features easy work-up and excellent functional group compatibility.

Synthesis of 3-keto-quinolines from enaminones, anilines and DMSO: Transition metal free one pot cascade

Tetrahedron ◽  
2019 ◽  
Vol 75 (30) ◽  
pp. 4024-4030 ◽  
Author(s):  
Sandip Balasaheb Wakade ◽  
Dipak Kumar Tiwari ◽  
Mandalaparthi Phanindrudu ◽  
Pushpendra ◽  
Dharmendra Kumar Tiwari
Keyword(s):  
Transition Metal ◽  
One Pot ◽  
Metal Free

Stereoselective three-component cascade synthesis of α-substituted 2,4-dienamides from gem-difluorochloro ethanes

2019 ◽  
Vol 55 (95) ◽  
pp. 14355-14358
Author(s):  
Shyamsundar Das ◽  
Nakeun Ko ◽  
Eunsung Lee ◽  
Sang Eun Kim ◽  
Byung Chul Lee
Keyword(s):  
Transition Metal ◽  
Claisen Rearrangement ◽  
Cascade Reaction ◽  
One Pot ◽  
Metal Free

Herein, we describe a new transition metal-free Claisen rearrangement for the synthesis of α-substituted 2,4-dienamide. This one-pot, stereoselective three-component cascade reaction affords various polysubstituted 2,4-dienamides in good yields.

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