scholarly journals Recent Advances in Synthetic Methods for Radioiodination

2020 ◽  
Vol 85 (13) ◽  
pp. 8300-8310
Author(s):  
Emmanuelle Dubost ◽  
Holly McErlain ◽  
Victor Babin ◽  
Andrew Sutherland ◽  
Thomas Cailly
Keyword(s):  
Synthetic Methods ◽  
Recent Advances

α-Aminoboronates: recent advances in their preparation and synthetic applications

2021 ◽  
Author(s):  
Wenbo Ming ◽  
Harjeet S. Soor ◽  
Xiaocui Liu ◽  
Alina Trofimova ◽  
Andrei K. Yudin ◽  
...  
Keyword(s):  
Building Blocks ◽  
Synthetic Methods ◽  
Mechanistic Explanations ◽  
Recent Advances

This review summarizes new methodology for the synthesis of α-aminoboronates, including asymmetric synthetic methods and mechanistic explanations of reactivity. Applications of α-aminoboronates as versatile synthetic building blocks are also discussed.

scholarly journals Recent Advances in Synthesis of 4-Arylcoumarins

Molecules ◽  
2018 ◽  
Vol 23 (10) ◽  
pp. 2417 ◽  
Author(s):  
Jong-Wha Jung ◽  
Nam-Jung Kim ◽  
Hwayoung Yun ◽  
Young Han
Keyword(s):  
Biological Activities ◽  
Synthetic Methods ◽  
Metal Catalysis ◽  
Naturally Occurring ◽  
Recent Advances ◽  
Formation Type ◽  
Privileged Scaffold ◽  
Acid Catalyzed ◽  
A Minor ◽  
Synthetic Approaches

4-Arylcoumarins (4-aryl-2H-1-benzopyran-2-one), also known as neoflavones, comprise a minor subclass of naturally occurring flavonoids. Because of their broad-spectrum biological activities, arylcoumarins have been attracting the attention of the organic and medicinal chemistry communities, and are considered as an important privileged scaffold. Since the development of Pechmann condensation, a classical acid-catalyzed condensation between phenol and β-keto-carboxylic acid, several versatile and efficient synthetic approaches for 4-arylcoumarins have been reported. This review summarizes recent advances in the synthesis of the 4-arylcoumarin scaffold by classifying them based on the final bond-formation type. In particular, synthetic methods executed under mild and highly efficient conditions, such as solvent-free reactions and transition metal catalysis, are highlighted.

scholarly journals Recent Advances in Nanoparticle Shape and Composition Regulation Based on Galvanic Replacement for Cancer Treatment

2018 ◽  
Author(s):  
Woojun Shin ◽  
Kyungtae Kang ◽  
Hongje Jang
Keyword(s):  
Drug Delivery ◽  
Ion Exchange ◽  
Cancer Treatment ◽  
Synthetic Methods ◽  
Galvanic Replacement ◽  
Future Outlook ◽  
Composition Control ◽  
Nanoparticle Shape ◽  
Recent Advances ◽  
Constituent Elements

Owing to their unique physicochemical properties, nanoparticles are used in a variety of ways in the field of cancer treatment, including imaging, drug delivery, and photothermal and photodynamic therapies. The fascinating properties of nanoparticles are determined by their size, morphology, and constituent elements, and various synthetic methods and post-synthetic techniques have been applied to control these factors. Herein, we present examples of shape and composition control through galvanic replacement, a technique that exploits redox potential differences between elements to induce spontaneous ion-exchange and highlight its specific contributions to cancer treatment applications. The present article identifies the recent advances in nanoparticle formation techniques and discusses the future outlook of the field.

scholarly journals Superelectrophiles: Recent Advances

Molecules ◽  
2020 ◽  
Vol 25 (14) ◽  
pp. 3281
Author(s):  
Douglas A. Klumpp ◽  
Maksim V. Anokhin
Keyword(s):  
Reactive Species ◽  
Synthetic Methods ◽  
Recent Advances

Superelectrophiles are reactive species that often carry multiple positive charges. They have been useful in numerous synthetic methods and they often exhibit highly unusual reactivities. Recent advances in superelectrophile chemistry are discussed in this review.

Recent advances in the development of highly enantioselective synthetic methods

1996 ◽  
Vol 68 (3) ◽  
pp. 569-580 ◽  
Author(s):  
Dieter Enders ◽  
Wolfgang Bettray
Keyword(s):  
Synthetic Methods ◽  
Recent Advances

scholarly journals Recent Advances in the Synthetic Biology of Natural Drugs

2021 ◽  
Vol 9 ◽  
Author(s):  
Chun-Qiang Li ◽  
Hong-Mei Lei ◽  
Qian-Yi Hu ◽  
Guo-Hong Li ◽  
Pei-Ji Zhao
Keyword(s):  
Synthetic Biology ◽  
Large Scale ◽  
Raw Materials ◽  
Pharmaceutical Products ◽  
Synthetic Methods ◽  
Present Review ◽  
Plant Metabolites ◽  
Advantages And Disadvantages ◽  
Recent Advances ◽  
Natural Drugs

Natural drugs have been transformed and optimized during the long process of evolution. These compounds play a very important role in the protection of human health and treatment of human diseases. Sustainable approaches to the generation of raw materials for pharmaceutical products have been extensively investigated in drug research and development because chemical synthesis is costly and generates pollution. The present review provides an overview of the recent advances in the synthetic biology of natural drugs. Particular attention is paid to the investigations of drugs that may be mass-produced by the pharmaceutical industry after optimization of the corresponding synthetic systems. The present review describes the reconstruction and optimization of biosynthetic pathways for nine drugs, including seven drugs from plant sources and two drugs from microbial sources, suggesting a new strategy for the large-scale preparation of some rare natural plant metabolites and highly bioactive microbial compounds. Some of the suggested synthetic methods remain in a preliminary exploration stage; however, a number of these methods demonstrated considerable application potential. The authors also discuss the advantages and disadvantages of the application of synthetic biology and various expression systems for heterologous expression of natural drugs. Thus, the present review provides a useful perspective for researchers attempting to use synthetic biology to produce natural drugs.

Two-dimensional group-VA nanomaterials beyond black phosphorus: synthetic methods, properties, functional nanostructures and applications

2019 ◽  
Vol 7 (45) ◽  
pp. 25712-25771 ◽  
Author(s):  
Rijun Gui ◽  
Hui Jin ◽  
Yujiao Sun ◽  
Xiaowen Jiang ◽  
Zejun Sun
Keyword(s):  
Black Phosphorus ◽  
Synthetic Methods ◽  
Two Dimensional ◽  
Functional Nanostructures ◽  
Dimensional Group ◽  
Recent Advances ◽  
Synthesis Properties

This review summarizes recent advances on synthesis, properties, functional nanostructures and applications of two-dimensional group-VA nanomaterials beyond black phosphorus.

Post-synthetic diamine-functionalization of MOF-74 type frameworks for effective carbon dioxide separation

2019 ◽  
Vol 48 (7) ◽  
pp. 2263-2270 ◽  
Author(s):  
Minjung Kang ◽  
Dong Won Kang ◽  
Chang Seop Hong
Keyword(s):  
Carbon Dioxide ◽  
High Density ◽  
Synthetic Methods ◽  
Carbon Dioxide Separation ◽  
Recent Advances

Post-synthetic methods are considered facile and effective for adjusting a material's properties. This frontiers article highlights recent advances in the post-synthetic modifications of MOF-74 type frameworks, whose high-density exposed metal sites are grafted by various diamines, leading to the tuning of CO2 adsorption capabilities.

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