scholarly journals α-Hydrogen Abstraction by •OH and •SH Radicals from Amino Acids and Their Peptide Derivatives

2016 ◽  
Vol 12 (4) ◽  
pp. 1606-1613 ◽  
Author(s):  
Bun Chan ◽  
Amir Karton ◽  
Christopher J. Easton ◽  
Leo Radom
Keyword(s):  
Amino Acids ◽  
Hydrogen Abstraction ◽  
Peptide Derivatives

FREE RADICALS OF BIOLOGICAL INTEREST: PART II. ELECTRON SPIN RESONANCE (ESR) SPECTRA OF 2537 A IRRADIATED AMINO ACIDS

1967 ◽  
Vol 45 (12) ◽  
pp. 1831-1839 ◽  
Author(s):  
W. F. Forbes ◽  
P. D. Sullivan
Keyword(s):  
Amino Acids ◽  
Electron Spin Resonance ◽  
Electron Spin ◽  
Hydrogen Abstraction ◽  
Esr Spectra ◽  
Side Chain ◽  
Biological Interest ◽  
Spin Resonance ◽  
Cyclohexadienyl Radical ◽  
Secondary Radical

Polycrystalline amino acids, when irradiated with 2537 Å light, afford a variety of electron spin resonance signals. These signals are generally stable at room temperature for relatively long periods of time. For a number of the spectra obtained, there is evidence that more than one radical species contributes to the observed spectra. The signals obtained frequently differ from those obtained on exposure to ionizing radiation. The postulated species formed can often be visualized as being formed by effective hydrogen abstraction from the alkyl-substituted tertiary carbon atom or from the —OH, —SH or —NH group contained in the side chain. For L-phenylalanine a secondary radical is obtained, which is ascribed to a cyclohexadienyl radical.

Thia-analogues of amino acids synthesis of peptide derivatives containing 3-thia-analogues of amino acids

Amino Acids ◽  
1992 ◽  
Vol 3 (1) ◽  
pp. 105-118 ◽  
Author(s):  
P. Hermann ◽  
H. Baumann ◽  
Ch. Herrnstadt ◽  
D. Glanz
Keyword(s):  
Amino Acids ◽  
Peptide Derivatives

γ-Radiation-induced carboxylation of pyrrolidine

1976 ◽  
Vol 29 (12) ◽  
pp. 2603 ◽  
Author(s):  
A Davison ◽  
NT Barker ◽  
DF Sangster
Keyword(s):  
Aqueous Solution ◽  
Amino Acids ◽  
Carboxylic Acid ◽  
Hydroxyl Radicals ◽  
Hydrogen Abstraction ◽  
Major Product ◽  
Amino Group ◽  
Γ Radiation ◽  
Neutral Aqueous Solution ◽  
Radiation Induced

Amino acids produced in the γ-radiation-induced carboxylation of pyrrolidine and formate in neutral aqueous solution have been studied. Two products only were found in the ratio 1 : 5.5. The minor product, proline, and the major product, pyrrolidine-3-carboxylic acid, have been characterized. Their presence indicates that the predominant site of hydrogen abstraction from pyrrolidine by radiation-generated hydroxyl radicals is β to the amino group.

scholarly journals Free radical destruction of hydroxyl-containing amino acids

2019 ◽  
pp. 3-13
Author(s):  
Anastasia A. Sladkova ◽  
Irina P. Edimecheva ◽  
Anna A. Sosnovskaya ◽  
Oleg I. Shadyro
Keyword(s):  
Amino Acids ◽  
Free Radical ◽  
Side Chain ◽  
Free Radical Processes ◽  
Peptide Derivatives ◽  
Novel Approaches ◽  
Radical Processes ◽  
Subsequent Decomposition ◽  
Reducing Properties

А new way of the free radical ROS- and HOCl-induced destruction of serine, threonine, and their peptide derivatives due to the nitrogen-centered radicals formation and their subsequent decomposition with the side chain elimination has been established. It has been shown that substances with reducing properties are inhibitors of this process, while oxygen does not affect the probability of its occurrence. The data obtained are relevant for the development of novel approaches to the search for effective free radical processes regulators.

Peptide Derivatives Containing Two Trifunctional Amino Acids. II

1955 ◽  
Vol 77 (3) ◽  
pp. 750-751 ◽  
Author(s):  
R. F. Fischer ◽  
R. R. Whetstone
Keyword(s):  
Amino Acids ◽  
Peptide Derivatives

Peptide Derivatives Containing Two Trifunctional Amino Acids

1954 ◽  
Vol 76 (20) ◽  
pp. 5076-5080 ◽  
Author(s):  
R. F. Fischer ◽  
R. R. Whetstone
Keyword(s):  
Amino Acids ◽  
Peptide Derivatives
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