Determination and Thermodynamic Analysis of the Solubility of Limonin in Eight Organic Solvents and Ethyl Acetate + 2-Propanol Binary Solvents from 283.2 to 323.2 K

2018 ◽  
Vol 63 (3) ◽  
pp. 642-650 ◽  
Author(s):  
Jie-Ping Fan ◽  
Tian-Tao Yuan ◽  
Jia-Xin Yu ◽  
Xue-Hong Zhang ◽  
Ya-Hui Cao
2021 ◽  
Vol 329 ◽  
pp. 115415
Author(s):  
Yuwei Hua ◽  
Genlei Wei ◽  
Shishuai Shi ◽  
Chunmei Cao ◽  
Xuening Zhang ◽  
...  

Author(s):  
JU Mollah ◽  
W Islam

Leaf, stem and roots of Thevetia peruviana (Pers) Schum. were extracted in four organic solvents; petroleum spirit, ethyl acetate, acetone and methanol and tested against the adults of Callosobruchus maculatus F. All the tested extracts effectively produced mortality of C. maculatus and their toxicity was in order of solvents: petroleum spirit>ethyl acetate>acetone>methanol. Root extract was the most toxic to C. maculatus. Females were more tolerant than males. Key words: Extract, mortality, solvent, Thevetia peruviana, Callosobruchus maculatus. DOI = 10.3329/jard.v5i1.1466 J Agric Rural Dev 5(1&2), 105-109, June 2007


1982 ◽  
pp. 1157-1162
Author(s):  
Masaru KIMURA ◽  
Shizuyo KURODA ◽  
Hiroko CHIBA ◽  
Mie TAKEUCHI ◽  
Natsumi KISHIDA

2017 ◽  
Vol 11 (1) ◽  
pp. 352-359 ◽  
Author(s):  
Gemechu Ameya ◽  
Aseer Manilal ◽  
Behailu Merdekios

Background: Controlling infectious disease using medicinal plants is the oldest healthcare known to mankind. Regardless of the enormous advances observed in modern medicine, medicinal plants are still playing vital roles. However, only a small proportion of medicinal plants are examined for bioactive compounds which may vary in different factors. This study aimed to evaluate phytochemical constituent and antimicrobial activities of Nicotiana tabacum L. extracted by different solvents against three set of bacteria. Methods: Nicotiana tabacum L. was collected from the Western Ethiopia and extracted in seven organic solvents. An in-vitro anti-bacterial activity of plant extracts was carried out by agar well diffusion assay against microbial type culture collection of human pathogens, clinical bacterial isolates, and biofilm forming bacteria. Gas Chromatographic and Mass Spectroscopic (GC-MS) analysis was used to determine the phytochemical constituents. Results: Antimicrobial activities of plant extract vary by extraction solvents; and ethyl acetate based extracts showed better antimicrobial activities. Of the experimental organisms, biofilm forming uropathogens were the most sensitive while clinical isolates were quite resistant. Analysis of the active ethyl acetate extract by GC-MS evinced a mixture of five volatile compounds; and Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (S) was the major compound detected. The overall results of the present study revealed that N. tabacum L extract has high antimicrobial activities against biofilm forming uropathogens. Conclusion: High antimicrobial activity was observed in ethyl acetate extract of N. tabacum against the biofilm forming bacteria whereas the clinically isolated bacteria were the most resistant group. The antibacterial property demonstrated could be due to Pyridine, 3-(1-methyl-2-pyrrolidinyl)-(S) with a broad spectrum of activity.


2019 ◽  
Vol 10 (4) ◽  
pp. 2733-2738
Author(s):  
Syaikhul Aziz ◽  
Elfahmi ◽  
Andreanus Andaja Soemardji ◽  
Sukrasno

This research was conducted to determine the total oryzanol content of various extracts and bioassay-guided isolation of active anti-hypercholesterolemic agent from Indonesian rice bran. Hot solvent extraction was done by reflux method using single and binary solvents, namely hexane, chloroform, ethyl acetate, dichloromethane, isopropanol, acetone, hexane-ethyl acetate (1:1, v/v), hexane-isopropanol (1:1, v/v), and chloroform-ethyl acetate (1:1, v/v). TLC densitometric was used to quantitatively analyze the total oryzanol content in various extracts. The hexane extract was selected for fractionation and evaluated for their anti-hypercholesterolemic activity. The structure of an isolated compound was determined on the basis of NMR and Mass spectroscopy. The total oryzanol content was obtained using various solvents ranging from 27.92 to 43.59 mg/100g rice bran, in which hexane extract showed the highest amount (43.59 ± 3.36 mg/100g rice bran). β-sitosterol has been isolated from rice bran hexane extract, which shows a significant decrease in serum total cholesterol level. In summary, hexane is the best solvent to extract oryzanol compound using reflux method, and β-sitosterol was suspected to be responsible for anti-hypercholesterolemic activity in addition to existing compound such as oryzanol that contained in the rice bran.


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