Solubility Behavior of N-Carbobenzoxy-l-2-phenylglycine in 11 Pure and a Binary Ethanol + Water Solvent Systems at 283.15–323.15 K

2021 ◽  
Author(s):  
Yue Zhao ◽  
Jingxuan Qiu ◽  
Shen Hu ◽  
Haishuang Huang ◽  
Hui He ◽  
...  
Keyword(s):  
Solubility Behavior ◽  
Water Solvent ◽  
Solvent Systems

Preparation of Ultra-Fine Clarithromycin Particles by Anti-Solvent Recrystallization

2016 ◽  
Vol 680 ◽  
pp. 534-537 ◽  
Author(s):  
Jing Xu
Keyword(s):  
Volume Ratio ◽  
Acetone Solution ◽  
Ultrafine Powders ◽  
Precipitation Temperature ◽  
Temperature And Precipitation ◽  
Water Solvent ◽  
Acetone Water ◽  
Ft Ir ◽  
Solvent Systems ◽  
The Mean

Ultrafine drug powders have higher bioavaibability than the larger signed particles. Ultrafine powders of clarithromycin were produced by anti-solvent recrystallization with the acetone - water solvent systems. The effects of volume ratio of clarithromycin acetone solution to anti-solvent, stirring speed, precipitation temperature and precipitation time on the preparation process were investigated. The results show that ultrafine powders can be yielded and well-controlled under the following optimal conditions: the volume ratio of clarithromycin acetone solution to anti-solvent 1:10, stirring speed 900 r/min, precipitation temperature 20°C, and precipitation time 10 min. The ultrafine powders with the rod-shape and the mean diameter of 1.8μm with the narrow distribution were successfully obtained. The yield of drug powders is more than 83%. The powders were analyzed with FT-IR and metalloscope. The purity of drug powders is more than 98%, according with Chinese Pharmacopoeia. The operation of the experiment was very simple, and the powders were separated easily.

Sol–gel synthesis of YAG/Al2O3 long fibres from water solvent systems

2000 ◽  
Vol 20 (5) ◽  
pp. 561-567 ◽  
Author(s):  
Kiyoshi Okada ◽  
Takayuki Motohashi ◽  
Yoshikazu Kameshima ◽  
Atsuo Yasumori
Keyword(s):  
Sol Gel ◽  
Water Solvent ◽  
Solvent Systems ◽  
Sol Gel Synthesis

scholarly journals Using water–solvent systems to estimate in vivo blood–tissue partition coefficients

2015 ◽  
Vol 9 (1) ◽  
Author(s):  
Caitlin E. Derricott ◽  
Emily A. Knight ◽  
William E. Acree ◽  
Andrew SID Lang
Keyword(s):  
Partition Coefficients ◽  
Water Solvent ◽  
Solvent Systems

Origin of Solubility Behavior of Polar π-Conjugated Crystals in Mixed Solvent Systems

2014 ◽  
Vol 14 (11) ◽  
pp. 6024-6032 ◽  
Author(s):  
Seung-Heon Lee ◽  
Min-Jeong Koo ◽  
Mojca Jazbinsek ◽  
O-Pil Kwon
Keyword(s):  
Mixed Solvent ◽  
Solubility Behavior ◽  
Solvent Systems
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