Comparative Study of Liquid–Liquid Equilibria for Aqueous Mixtures of Phosphoric Acid with Two Structurally Similar Carbonyl Compounds: Measurement and Correlation

2020 ◽  
Vol 65 (11) ◽  
pp. 5341-5351
Author(s):  
Ali Ghanadzadeh Gilani ◽  
Saniyeh Ahmadifar ◽  
Touba Taki
Keyword(s):  
Phosphoric Acid ◽  
Comparative Study ◽  
Carbonyl Compounds ◽  
Aqueous Mixtures

Direct Asymmetric α-Hydroxylation of Cyclic α-Branched Ketones through Enol Catalysis

Synlett ◽  
2018 ◽  
Vol 30 (01) ◽  
pp. 49-53 ◽  
Author(s):  
Benjamin List ◽  
Grigory Shevchenko ◽  
Gabriele Pupo
Keyword(s):  
Natural Products ◽  
Phosphoric Acid ◽  
Carbonyl Compounds ◽  
Tertiary Alcohols ◽  
Chiral Phosphoric Acid

Enantiopure α-hydroxy carbonyl compounds are common scaffolds in natural products and pharmaceuticals. Although indirect approaches towards their synthesis are known, direct asymmetric methodologies are scarce. Herein, we report the first direct asymmetric α-hydroxylation of α-branched ketones through enol catalysis, enabling a facile access to valuable α-keto tertiary alcohols. The transformation, characterized by the use of nitrosobenzene as the oxidant and a new chiral phosphoric acid as the catalyst, delivers a good scope and excellent enantioselectivities.

Cleavage (Deprotection) of Selenoacetals to Carbonyl Compounds; A Comparative Study

Synthesis ◽  
1979 ◽  
Vol 1979 (11) ◽  
pp. 877-880 ◽  
Author(s):  
A. Burton ◽  
L. Hevesi ◽  
W. Dumont ◽  
A. Cravador ◽  
A. Krief
Keyword(s):  
Comparative Study ◽  
Carbonyl Compounds
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