Solubility Determination and Thermodynamic Properties of Bezafibrate in Pure and Binary Mixed Solvents

2020 ◽  
Vol 65 (4) ◽  
pp. 2156-2169
Author(s):  
Mengmeng Liu ◽  
Shui Wang ◽  
Chao Qu ◽  
Zhichao Zhang ◽  
Yixin Qu
Keyword(s):  
Thermodynamic Properties ◽  
Mixed Solvents ◽  
Solubility Determination

Co-solvence phenomenon and thermodynamic properties of edaravone in pure and mixed solvents

2019 ◽  
Vol 138 ◽  
pp. 304-312 ◽  
Author(s):  
Rongrong Li ◽  
Lusha Yao ◽  
Arshad Khan ◽  
Bo Zhao ◽  
Dehua Wang ◽  
...  
Keyword(s):  
Thermodynamic Properties ◽  
Mixed Solvents ◽  
Pure And Mixed Solvents

Impacts of polyols and temperature on the micellization, interaction and thermodynamics behavior of the mixture of tetradecyltrimethylammonium bromide and polyvinyl alcohol

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Sharmin Sultana ◽  
Abdullah Al Mamun ◽  
Shahina Aktar ◽  
Shamim Mahbub ◽  
Kareem Yusuf ◽  
...  
Keyword(s):  
Thermodynamic Properties ◽  
Polyvinyl Alcohol ◽  
Hydrophobic Interactions ◽  
Specific Conductivity ◽  
Mixed Solvents ◽  
Conductivity Measurement ◽  
Micelle Formation ◽  
Tetradecyltrimethylammonium Bromide ◽  
Delta G ◽  
Free Energy Of Micellization

Abstract Herein, the aggregation manner of the mixture of polyvinyl alcohol (PVA) and tetradecyltrimethylammonium bromide (TTAB) was performed in polyols (glucose, maltose and galactose) media over 300.55–320.55 K temperatures range with 5 K interval through conductivity measurement method. The micelle formation of TTAB + PVA mixture was identified by the assessment of critical micelle concentration (CMC) from the plots of specific conductivity (κ) versus TTAB concentration. The degree of micelle ionization (α), the extent of bound counter ions (β) as well as thermodynamic properties ( Δ G m 0 ${\Delta}{G}_{m}^{0}$ , Δ H m 0 ${\Delta}{H}_{m}^{0}$ and Δ S m 0 ${\Delta}{S}_{m}^{0}$ ) of TTAB + PVA systems have been estimated. The CMC values reveal that the micelle formation of TTAB + PVA mixture experience an enhancement in the manifestation of polyols. The values of free energy of micellization ( Δ G m 0 ${\Delta}{G}_{m}^{0}$ ) are negative for the TTAB + PVA system in aqueous polyols media, suggesting a spontaneous aggregation phenomenon. The Δ H m 0 ${\Delta}{H}_{m}^{0}$ and Δ S m 0 ${\Delta}{S}_{m}^{0}$ values of TTAB + PVA systems direct that the PVA molecule interacts with TTAB through the exothermic, ion-dipole, and hydrophobic interactions. The thermodynamic properties of transfer were also determined for the move of TTAB + PVA mixture from H2O to water + polyols mixed solvents. The values of compensation temperature (T c) and intrinsic enthalpy gain ( Δ H m 0 , ∗ ${\Delta}{H}_{m}^{0,\ast }$ ) were evaluated and discussed for the studied system.

Dissolution behavior and thermodynamic properties of apixaban in pure and mixed solvents

2020 ◽  
Vol 144 ◽  
pp. 105949 ◽  
Author(s):  
Cunbin Du ◽  
Yang Cong ◽  
Ying Zhang ◽  
Yi Xue ◽  
Bin Qiao ◽  
...  
Keyword(s):  
Thermodynamic Properties ◽  
Mixed Solvents ◽  
Dissolution Behavior ◽  
Pure And Mixed Solvents
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