Potentially High Value Conjugated Linolenic Acids (CLnA) in Melon Seed Waste

2019 ◽  
Vol 67 (37) ◽  
pp. 10306-10312 ◽  
Author(s):  
Dong Hao Wang ◽  
Zhen Wang ◽  
Kim Phuong Le ◽  
J. Raven Cortright ◽  
Hui Gyu Park ◽  
...  
Keyword(s):  
Melon Seed ◽  
Conjugated Linolenic Acids

scholarly journals A comparative study on quality parameters of pumpkin, melon and sunflower oils during thermal treatment

OCL ◽  
2019 ◽  
Vol 26 ◽  
pp. 32 ◽  
Author(s):  
Zhana Petkova ◽  
Ginka Antova
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Thermal Treatment ◽  
Microwave Heating ◽  
Acid Composition ◽  
Seed Oil ◽  
Conventional Heating ◽  
Melon Seed ◽  
Sunflower Oils ◽  
Melon Seed Oil

Current paper reveals the impact of thermal treatment on the quality of two seed oils – pumpkin and melon compared to the quality of the most used oil – sunflower oil. Conventional and microwave heating were used for processing the oils. The duration of the thermal treatment was 9, 12 and 18 min for the conventional heating. The microwave heating was performed with two microwave powers of the equipment (600 W and 900 W) for 3, 6, 9 and 12 min. At every stage of the thermal processing were determined acid and peroxide value, the absorbance of the oils at 232 and 268 nm, tocopherol and fatty acid composition. It was observed that the degree of oxidation of the examined oils during microwave and conventional heating increased with the duration of the thermal process and the power of the microwaves. Also, the two methods of heating had a little impact on the processes leading to the formation of free fatty acids. Total tocopherols of the melon seed oil were more stable to thermal treatment. The amount of linoleic acid decreased in the pumpkin and sunflower oils during microwave treatment, while that of oleic and palmitic acid relatively increased. The biggest change in the fatty acid composition of both oils was found during microwave heating at 900W. The changes in fatty acid composition of thermally treated melon seed oil were insignificant. Overall, melon seed oil was observed to be more thermally stable than pumpkin and sunflower oils.

scholarly journals Ferroptotic cell death triggered by conjugated linolenic acids is mediated by ACSL1

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Alexander Beatty ◽  
Tanu Singh ◽  
Yulia Y. Tyurina ◽  
Vladimir A. Tyurin ◽  
Svetlana Samovich ◽  
...  
Keyword(s):  
Cell Death ◽  
Therapeutic Potential ◽  
Neutral Lipids ◽  
Cell Types ◽  
Lipid Hydroperoxides ◽  
Conjugated Linolenic Acids ◽  
Cellular Lipids ◽  
Transcriptional Changes ◽  
Acyl Chains ◽  
Tumor Growth And Metastasis

AbstractFerroptosis is associated with lipid hydroperoxides generated by the oxidation of polyunsaturated acyl chains. Lipid hydroperoxides are reduced by glutathione peroxidase 4 (GPX4) and GPX4 inhibitors induce ferroptosis. However, the therapeutic potential of triggering ferroptosis in cancer cells with polyunsaturated fatty acids is unknown. Here, we identify conjugated linoleates including α-eleostearic acid (αESA) as ferroptosis inducers. αESA does not alter GPX4 activity but is incorporated into cellular lipids and promotes lipid peroxidation and cell death in diverse cancer cell types. αESA-triggered death is mediated by acyl-CoA synthetase long-chain isoform 1, which promotes αESA incorporation into neutral lipids including triacylglycerols. Interfering with triacylglycerol biosynthesis suppresses ferroptosis triggered by αESA but not by GPX4 inhibition. Oral administration of tung oil, naturally rich in αESA, to mice limits tumor growth and metastasis with transcriptional changes consistent with ferroptosis. Overall, these findings illuminate a potential approach to ferroptosis, complementary to GPX4 inhibition.

Thermal transitions of melon seed proteins

1984 ◽  
Vol 13 (4) ◽  
pp. 309-316 ◽  
Author(s):  
J Onuora
Keyword(s):  
Seed Proteins ◽  
Thermal Transitions ◽  
Melon Seed

Characterization and Stability Studies of Egusi Melon Seed Oil (Citrullus colocynthis L.)

2021 ◽  
Vol 46 (2) ◽  
Author(s):  
C.O. Ajenu ◽  
M.E. Ukhun ◽  
C. Imoisi ◽  
E.E. Imhontu ◽  
L.E. Irede ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Free Fatty Acid ◽  
Iodine Value ◽  
Peroxide Value ◽  
Seed Oil ◽  
Thiobarbituric Acid ◽  
Acid Value ◽  
Melon Seed ◽  
Thiobarbituric Acid Value ◽  
Melon Seed Oil

The physical value of oil depends upon its chemical composition, even today these values play a vital role while using different oil for industrial products and also, despite the vast nutritional and medicinal significance of egusi melon, there are little details on the shell life and stability of its oil over time. Therefore, the influence of time and temperature on melon seed oil was investigated at temperatures of 0oC and 30oC at different weeks to ascertain its physicochemical value and storage stability. For week zero, at 0oC and ambient temperature (30oC), the result revealed iodine value 124.09, Acid value 3.64 mgNaOH/g, Free Fatty Acid value 1.84 mgNaOH/g, Saponification 217.35 mgKOH/g, Peroxide value 1.25 mg/g oil, pH 5.89 and thiobarbituric acid value 0.1383 respectively. In the 5th week, at 30oC, the result revealed iodine value 91.1543, acid value 12.8921 mgNaOH/g, free fatty acid value 6.4988 mgNaOH/g, Saponification 346.42 mgKOH/g, Peroxide value 9.5mg/g oil, pH 3.2 and thiobarbituric acid value 0.413 respectively. Also at 0oC in the 5th week, the results were observed as follow: Iodine value 102.53, Acid value 7.96 mgNaOH/g, Free Fatty Acid value 4.01 mgNaOH/g, saponification 287.51 mgKOH/g, Peroxide value 6.1 mg/g oil, pH 5.05, and thiobarbituric acid value 0.2658 respectively. Refrigeration (0oC) of oil reduced the rate of most of the oxidative deterioration that produces rancidity. These values are within recommended range for edible oils. These results indicate that egusi melon oil could be a good source of table oil. The statistical results show that there was a significant difference between the melon seed oil stored at 0oC and 30oC (P < 0.001).

Formulation And Antioxidant Property Of Bitter Melon Seeds Oil Loaded Into SNEDDS Systems As A Nutraceutical

2021 ◽  
Author(s):  
Lina Winarti ◽  
Lusia Oktora Ruma Kumala Sari ◽  
Evi Umayah Ulfa ◽  
Dwi Ayu Samsuri
Keyword(s):  
Antioxidant Activity ◽  
Seed Oil ◽  
Ph Value ◽  
Reducing Power ◽  
Antioxidant Property ◽  
Bitter Melon ◽  
Antioxidant Power ◽  
Melon Seed ◽  
Melon Seed Oil ◽  
Melon Seeds

Bitter melon seeds oil is less soluble in the gastrointestinal tract and has low absorption. Therefore, a self-nanoemulsion dosage form needed to support its absorption and increase its stability. This study aimed to formulate bitter melon seeds oil into a self-nano emulsifying drug delivery system (SNEDDS) and evaluate its antioxidant activity using the Ferric Reducing Antioxidant Power (FRAP) method. The SNEDDS formulation uses bitter melon seed oil as the active ingredient and the oil phase, cremophor RH 40 as a surfactant, and glycerin as a co-surfactant. The results showed that the best SNEDDS formula obtains a ratio of oil: Smix (surfactant mixture) of 1:4. The best formula transmittance was 97.35 ± 0.04% with an emulsification time of 15.69 ± 0.06 seconds, a pH value of 6.87 ± 0.08, and a particle size of 31.8 ± 16.3 nm. Thermodynamic stability and robustness to dilution tests show the preparation is stable and resistant to various dilutions and pH. The antioxidant activity of bitter melon seed oil before and after being formulated into SNEDDS resulted in 62.73% and 50.31% reducing power. This result is not differences significantly. This study concluded that bitter melon seeds oil SNEDDS has good physical characteristics, stability, and no antioxidant activity changes.

scholarly journals EFFECT OF PLANT EXTRACTS ON SPORULATION AND SPORE GERMINATION OF STORED MELON SEED FUNGI

2014 ◽  
Vol 1 (1) ◽  
pp. 21-29
Author(s):  
Amadi E. ◽  
Deleke E. ◽  
Olahan G. ◽  
Garuba T. ◽  
Adebola M.O.
Keyword(s):  
Plant Extracts ◽  
Spore Germination ◽  
Fusarium Species ◽  
Phytochemical Screening ◽  
Nutrient Contents ◽  
Melon Seed ◽  
Storage Fungi ◽  
Test Organisms ◽  
Melon Seeds

Frequently, stored melon seeds fail to preserve to their time of use. Storage fungi invade these seeds and cause their deterioration. A study was, therefore, carried out to determine the effect of guava (Psidiumguajava L.) leaf and ginger (Zingiberofficinale) rhizome extracts on the sporulation and spore germination of the invading seed fungi.Dried leaves and rhizomes were ground in sterile mortar, filtered through a wire sieve and then extracted usingthree different solvents. Results revealed that both extracts hindered sporulation and spore germination in the four fungi tested namely: Aspergillusflavus, A. niger, Rhizopusstolonifer and Fusarium species. The effect of the extracts on the test organisms increased with concentration of the extracts. Phytochemical screening confirmed the presence of alkaloids, saponins, lipids,tannins, flavonoids, and steroids. A reduction in nutrient contents was also observed in infested melon seeds. These results are significant and would serve as a template for planning the control of storage fungi in melon seeds in particular and other crop produce in general.

scholarly journals Feasibility Study of Melon Seed Oil as a Source of Biodiesel

2015 ◽  
Vol 03 (08) ◽  
pp. 24-27 ◽  
Author(s):  
Kennedy Izuchukwu Ogunwa ◽  
Samuel Ofodile ◽  
Ozioma Achugasim
Keyword(s):  
Feasibility Study ◽  
Seed Oil ◽  
Melon Seed ◽  
Melon Seed Oil
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