Modulation of the Fecal Microbiota in Sprague-Dawley Rats Using Genetically Modified and Isogenic Corn Lines

2018 ◽  
Vol 66 (2) ◽  
pp. 551-561 ◽  
Author(s):  
Penggao Li ◽  
Chun Yang ◽  
Rong Yue ◽  
Yaping Zhen ◽  
Qin Zhuo ◽  
...  
Keyword(s):  
Genetically Modified ◽  
Fecal Microbiota ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

Testing Safety of Genetically Modified Products of Rice: Case Study on Sprague Dawley Rats

2019 ◽  
Vol 55 (8) ◽  
pp. 962-968
Author(s):  
M. Shirdeli ◽  
Y. L. Orlov ◽  
G. Eslami ◽  
B. Hajimohammadi ◽  
L. E. Tabikhanova ◽  
...  
Keyword(s):  
Genetically Modified ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

scholarly journals The effect of genetically modified Lactobacillus plantarum 590 on the gut health of sprague-dawley rats

IUBMB Life ◽  
2012 ◽  
Vol 64 (7) ◽  
pp. 617-627 ◽  
Author(s):  
Hai-Yan Liu ◽  
Wen-Tao Xu ◽  
Yan-Fang Yuan ◽  
Si-Shuo Cao ◽  
Xiao-Yun He ◽  
...  
Keyword(s):  
Lactobacillus Plantarum ◽  
Genetically Modified ◽  
Gut Health ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

scholarly journals A 90-Day Dietary Toxicity Study of Genetically Modified Rice T1C-1 Expressing Cry1C Protein in Sprague Dawley Rats

PLoS ONE ◽  
2012 ◽  
Vol 7 (12) ◽  
pp. e52507 ◽  
Author(s):  
Xueming Tang ◽  
Fangting Han ◽  
Kai Zhao ◽  
Yan Xu ◽  
Xiao Wu ◽  
...  
Keyword(s):  
Genetically Modified ◽  
Toxicity Study ◽  
Sprague Dawley ◽  
Genetically Modified Rice ◽  
Sprague Dawley Rats ◽  
Dietary Toxicity

A 90-day subchronic feeding study of genetically modified maize expressing Cry1Ac-M protein in Sprague–Dawley rats

2012 ◽  
Vol 50 (9) ◽  
pp. 3215-3221 ◽  
Author(s):  
Pengfei Liu ◽  
Xiaoyun He ◽  
Delong Chen ◽  
Yunbo Luo ◽  
Sishuo Cao ◽  
...  
Keyword(s):  
Genetically Modified ◽  
M Protein ◽  
Genetically Modified Maize ◽  
Sprague Dawley ◽  
Feeding Study ◽  
Sprague Dawley Rats

Subchronic feeding study of stacked trait genetically-modified soybean (3Ø5423×40-3-2) in Sprague–Dawley rats

2012 ◽  
Vol 50 (9) ◽  
pp. 3256-3263 ◽  
Author(s):  
Xiaozhe Qi ◽  
Xiaoyun He ◽  
Yunbo Luo ◽  
Shuangying Li ◽  
Shiying Zou ◽  
...  
Keyword(s):  
Genetically Modified ◽  
Sprague Dawley ◽  
Genetically Modified Soybean ◽  
Feeding Study ◽  
Sprague Dawley Rats

Allergenicity test of genetically modified soybean in Sprague Dawley rats

2001 ◽  
Vol 24 (3) ◽  
pp. 256-261 ◽  
Author(s):  
Hyun Sung Chang ◽  
Youn Kyoung Bae ◽  
Si Kyu Lim ◽  
Tae Cheon Jeong ◽  
Hyung Soo Kim ◽  
...  
Keyword(s):  
Genetically Modified ◽  
Sprague Dawley ◽  
Genetically Modified Soybean ◽  
Sprague Dawley Rats

scholarly journals Safety assessment of genetically modified rice expressing Cry1Ab protein in Sprague–Dawley rats

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Bahador Hajimohammadi ◽  
Gilda Eslami ◽  
Hengameh Zandi ◽  
Mohammad Hassan Ehrampoush ◽  
Azar Naimi ◽  
...  
Keyword(s):  
Urine Analysis ◽  
Genetically Modified ◽  
Hematological Parameters ◽  
Sprague Dawley ◽  
Cry1ab Protein ◽  
Bt Rice ◽  
Sprague Dawley Rats ◽  
Significant Difference ◽  
Gene Expressing ◽  
Hormonal Levels

AbstractRice is considered one of the most important staple food crops. Genetically modified (GM) Bt rice, harbored cry1Ab gene expressing the insect-resistance protein has been developed to resistance to the insects. In this study, we assessed the safety of the GM Bt rice on Sprague–Dawley rats for 90 days. Totally, 120 rats in both sexes were used for three different diets, including 50% GM Bt rice, feeding with 50% rice, and standard feeding. Each 40 SD rats including 20 males and 20 females were considered as each diet. The clinical variables such as body weight and food consumption were measured and a range of clinical tests was examined, including hematology, serum chemistry parameters, urinalysis profile, thyroid, and sex hormone levels. Pathological assessments were also done. The results showed that the mean weekly feed utilization (%) had no significant difference among the studied groups. Also, blood biochemistry, hematological parameters, urine analysis, and hormonal levels had no significant differences among the groups. However, alanine aminotransferase was less in males versus female feeding with GM Bt rice. No histopathological changes were observed among the groups. In conclusion, this study demonstrated that GM Bt rice had no obvious adverse effects on rats' health.

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