Anti-inflammatory Effect of Essential Oil fromCitrus aurantiumL. var.amaraEngl

2017 ◽  
Vol 65 (39) ◽  
pp. 8586-8594 ◽  
Author(s):  
Chun-Yan Shen ◽  
Jian-Guo Jiang ◽  
Wei Zhu ◽  
Qin Ou-Yang
Keyword(s):  
Essential Oil ◽  
Anti Inflammatory ◽  
Inflammatory Effect

scholarly journals Effect of Essential Oils from Ginger (Zingiber officinale) and Turmeric (Curcuma longa) Rhizomes on Some Inflammatory Biomarkers in Cadmium Induced Neurotoxicity in Rats

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Ayodele Jacob Akinyemi ◽  
Philip Adeyemi Adeniyi
Keyword(s):  
Prefrontal Cortex ◽  
Essential Oil ◽  
Essential Oils ◽  
Neurological Diseases ◽  
Curcuma Longa ◽  
Zingiber Officinale ◽  
Inflammatory Biomarkers ◽  
Tnf Alpha ◽  
Anti Inflammatory ◽  
Inflammatory Effect

Studies have revealed that anti-inflammatory agents could provide beneficial effect in lowering the incidence/progression of neurological diseases. Hence, this study sought to investigate the effect of essential oils from Nigeria ginger and turmeric rhizomes on some cytokines in cadmium induced neurotoxicity. The result revealed that essential oil from ginger and turmeric rhizomes exerts anti-inflammatory effect by preventing alterations of some cytokines/inflammatory biomarkers (IL-6, IL-10 and TNF-Alpha) levels and inhibits both hippocampus and prefrontal cortex acetylcholinesterase (AChE) and adenosine deaminase (ADA) activities (important enzymes relevant in the management/prevention of neurodegenerative diseases) in Cd treated rats. In conclusion, essential oil from ginger and turmeric rhizomes exerts anti-inflammatory properties in Cd induced neurotoxicity. The observed effect could be due to the volatile compounds as revealed by GC-MS analysis.

scholarly journals Antinociceptive and anti-inflammatory effect of Lippia pedunculosa Hayek essential oil and its β-cyclodextrin inclusion complex

2021 ◽  
Vol 20 (2) ◽  
pp. 162-176
Author(s):  
Renan Marinho Braga ◽  
◽  
Humberto Hugo Nunes de Andrade ◽  
Humberto de Carvalho Aragao Neto ◽  
Ryldene Marques Duarte da Cruz ◽  
...  
Keyword(s):  
Essential Oil ◽  
Inclusion Complex ◽  
Antinociceptive Effect ◽  
Experimental Models ◽  
Complex Formulation ◽  
Cyclodextrin Inclusion ◽  
Leucocyte Migration ◽  
Prevalence Of Pain ◽  
Anti Inflammatory ◽  
Inflammatory Effect

Lippia pedunculosa Hayek (EOLp) presents tripanocid and amebicid effects. However essential oil needs to be further studied in experimental models of analgesia and inflammation once the prevalence of pain in the population generates great suffering and disability and the drugs most often used have undesirable side effects. We also evaluated whether the inclusion complex formulation EOLp/β-cyclodextrin (β-CD) was able to improve the antinociceptive activity of the EOLp alone. Data were evaluated by analysis of variance (ANOVA), followed by Tukey’s test. Differences were considered significant if p<0.05. EOLp presented better antinociceptive effect when compared to the EOLp/β-CD inclusion complex. Thus, cyclodextrins appear not to be efficient for essential oils with peroxide substances. However, in peritonitis, EOLp reduced total leucocyte migration and IL-1β levels in the peritoneal fluid, which confirmed its anti-inflammatory effect. The observed effects suggest that EOLp is the best promising option for the treatment of inflammation and pain-related disorders.

scholarly journals Anti-Inflammatory Investigations of Extracts of Zanthoxylum rhetsa

2021 ◽  
Vol 2021 ◽  
pp. 1-15
Author(s):  
Chureeporn Imphat ◽  
Pakakrong Thongdeeying ◽  
Arunporn Itharat ◽  
Sumalee Panthong ◽  
Sunita Makchuchit ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Essential Oil ◽  
Ethanolic Extract ◽  
Inhibitory Effect ◽  
No Production ◽  
Water Distillation ◽  
Raw264.7 Macrophages ◽  
Tnf Α ◽  
Anti Inflammatory ◽  
Inflammatory Effect

Zanthoxylum rhetsa has been consumed in the diet in northern Thailand and also used as a medicament in ancient scripture for arthropathies. Thus, this study aimed to evaluate the activity of various extracts from differential parts of Z. rhetsa via inhibition of inflammatory mediators (NO, TNF-α, and PGE2) in RAW264.7 macrophages. The chemical composition in active extracts was also analyzed by GC/MS. The parts of this plant studied were whole fruits (F), pericarp (P), and seed (O). The methods of extraction included maceration in hexane, 95% ethanol and 50% ethanol, boiling in water, and water distillation. The results demonstrated that the hexane and 95% ethanolic extract from pericarp (PH and P95) and seed essential oil (SO) were the most active extracts. PH and P95 gave the highest inhibition of NO production with IC50 as 11.99 ± 1.66 μg/ml and 15.33 ± 1.05 μg/ml, respectively, and they also showed the highest anti-inflammatory effect on TNF-α with IC50 as 36.08 ± 0.55 μg/ml and 34.90 ± 2.58 μg/ml, respectively. PH and P95 also showed the highest inhibitory effect on PGE2 but less than SO with IC50 as 13.72 ± 0.81 μg/ml, 12.26 ± 0.71 μg/ml, and 8.61 ± 2.23 μg/ml, respectively. 2,3-Pinanediol was the major anti-inflammatory compound analyzed in PH (11.28%) and P95 (19.82%) while terpinen-4-ol constituted a major anti-inflammatory compound in SO at 35.13%. These findings are the first supportive data for ethnomedical use for analgesic and anti-inflammatory activity in acute (SO) and chronic (PH and P95) inflammation.

Composition and anti-Inflammatory effect of the common myrtle (Myrtus communisL.) essential oil growing wild in Algeria

2018 ◽  
Vol 16 (S1) ◽  
pp. S143-S148
Author(s):  
M. Touaibia
Keyword(s):  
Essential Oil ◽  
Positive Control ◽  
Inflammatory Activity ◽  
Myrtus Communis ◽  
Paw Edema ◽  
High Fraction ◽  
The Common ◽  
Anti Inflammatory ◽  
Different Doses ◽  
Inflammatory Effect

This study was designed to evaluate the chemical composition and anti-inflammatory activity of the common myrtle (Myrtus communisL.) essential oil. The composition ofMyrtus communisL. essential oil, extracted by steam distillation, was characterized by a high fraction (80.9%) of oxygenated monoterpenes. The major components were myrtenyl acetate (38.7%), eucalyptol (12.7%), α-pinene (13.7%), and linalool (7.00%). The chemical profile of this essential oil allows us to classify it as myrtényle acétate/α- pinène chemotype, but with atypical proportions, related to the harvesting area. In the carrageenan-induced paw edema, five different groups were established and the essential oil was administered orally in three different doses. The common myrtle essential oil (100 mg/kg) was able to reduce the paw edema, with a comparable effect to that observed with diclofenac (positive control). This is the first report to demonstrate a significant anti-inflammatory activity of Algerian common myrtle essential oil.

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