Structural Characterization of Lignin-Carbohydrate Complexes (LCCs) and Their Biotransformation by Intestinal Microbiota In Vitro

2021 ◽  
Author(s):  
Ran Zhang ◽  
Lei Wang ◽  
Chengcheng Shi ◽  
Qipeng Shi ◽  
Fuying Ma ◽  
...  
Keyword(s):  
Intestinal Microbiota ◽  
Structural Characterization

Structural characterization of naphthalene sulfonamides and a sulfonate ester and their in vitro efficacy against Leishmania tarentolae promastigotes

2021 ◽  
Vol 45 (10) ◽  
pp. 4791-4801
Author(s):  
Edward W. Li ◽  
Jade Katinas ◽  
Marjorie A. Jones ◽  
Christopher G. Hamaker
Keyword(s):  
Biological Activity ◽  
Structural Characterization ◽  
Leishmania Tarentolae ◽  
Sulfonate Ester

Structural and biological activity analyses of two naphthalene sulfonamides and a naphthalene sulfonate ester.

Structural characterization of soybean milk particles during in vitro digestive/non-digestive simulation

LWT ◽  
2019 ◽  
Vol 108 ◽  
pp. 326-331 ◽  
Author(s):  
Weilin Liu ◽  
Hanghang Lou ◽  
Christos Ritzoulis ◽  
Xiaoze Chen ◽  
Ping Shen ◽  
...  
Keyword(s):  
Structural Characterization ◽  
Soybean Milk

scholarly journals Structural characterization of a novel mannogalactoglucan from Fortunella margarita and its simulated digestion in vitro

2019 ◽  
Vol 133 ◽  
pp. 110778 ◽  
Author(s):  
Peilin Chen ◽  
Yan Lin ◽  
Yueyu Chen ◽  
Qing Chang ◽  
Baodong Zheng ◽  
...  
Keyword(s):  
Structural Characterization ◽  
Simulated Digestion

Structural characterization of electrochemically and in vitro biologically generated oxidation products of atorvastatin using UHPLC/MS/MS

2013 ◽  
Vol 405 (23) ◽  
pp. 7181-7193 ◽  
Author(s):  
Robert Jirásko ◽  
Tomáš Mikysek ◽  
Vitaliy Chagovets ◽  
Ivan Vokřál ◽  
Michal Holčapek
Keyword(s):  
Structural Characterization ◽  
Oxidation Products

De novo formation and ultra-structural characterization of a fiber-producing human hair follicle equivalent in vitro

2011 ◽  
Vol 152 (3) ◽  
pp. 108-112 ◽  
Author(s):  
Gerd Lindner ◽  
Reyk Horland ◽  
Ilka Wagner ◽  
Beren Ataç ◽  
Roland Lauster
Keyword(s):  
Hair Follicle ◽  
Structural Characterization ◽  
Human Hair ◽  
De Novo ◽  
Human Hair Follicle

scholarly journals In Vitro Anticancer Activity and Structural Characterization of Ubiquinones from Antrodia cinnamomea Mycelium

Molecules ◽  
2017 ◽  
Vol 22 (5) ◽  
pp. 747 ◽  
Author(s):  
I-Chuan Yen ◽  
Shih-Yu Lee ◽  
Kuen-Tze Lin ◽  
Feng-Yi Lai ◽  
Mao-Tien Kuo ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Structural Characterization ◽  
Antrodia Cinnamomea

scholarly journals Enantioseparation, in vitro testing, and structural characterization of triple-binding reactivators of organophosphate-inhibited cholinesterases

2020 ◽  
Vol 477 (15) ◽  
pp. 2771-2790 ◽  
Author(s):  
Nikola Maraković ◽  
Anamarija Knežević ◽  
Igor Rončević ◽  
Xavier Brazzolotto ◽  
Zrinka Kovarik ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Proton Transfer ◽  
Structural Characterization ◽  
Active Site ◽  
In Vitro Testing ◽  
Active Site Residues

The enantiomers of racemic 2-hydroxyimino-N-(azidophenylpropyl)acetamide-derived triple-binding oxime reactivators were separated, and tested for inhibition and reactivation of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibited with tabun (GA), cyclosarin (GF), sarin (GB), and VX. Both enzymes showed the greatest affinity toward the methylimidazole derivative (III) of 2-hydroxyimino-N-(azidophenylpropyl)acetamide (I). The crystal structure was determined for the complex of oxime III within human BChE, confirming that all three binding groups interacted with active site residues. In the case of BChE inhibited by GF, oximes I (kr = 207 M−1 min−1) and III (kr = 213 M−1 min−1) showed better reactivation efficiency than the reference oxime 2-PAM. Finally, the key mechanistic steps in the reactivation of GF-inhibited BChE with oxime III were modeled using the PM7R6 method, stressing the importance of proton transfer from Nε of His438 to Oγ of Ser203 for achieving successful reactivation.

scholarly journals In Vitro Functional and Structural Characterization of A Synthetic Clinical Pulmonary Surfactant with Enhanced Resistance to Inhibition

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Mercedes Echaide ◽  
Chiara Autilio ◽  
Elena López-Rodríguez ◽  
Antonio Cruz ◽  
Jesús Pérez-Gil
Keyword(s):  
Structural Characterization ◽  
Pulmonary Surfactant ◽  
Enhanced Resistance
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