Eugenol Alleviates Dextran Sulfate Sodium-Induced Colitis Independent of Intestinal Microbiota in Mice

2021 ◽  
Author(s):  
Shuai Chen ◽  
Xin Wu ◽  
Shengguo Tang ◽  
Jie Yin ◽  
Zehe Song ◽  
...  
Keyword(s):  
Intestinal Microbiota ◽  
Dextran Sulfate ◽  
Dextran Sulfate Sodium

Ingestion of Low Dose Pyroglutamyl Leucine Improves Dextran Sulfate Sodium-Induced Colitis and Intestinal Microbiota in Mice

2013 ◽  
Vol 61 (37) ◽  
pp. 8807-8813 ◽  
Author(s):  
Sayori Wada ◽  
Kenji Sato ◽  
Ryoko Ohta ◽  
Eri Wada ◽  
Yukiho Bou ◽  
...  
Keyword(s):  
Intestinal Microbiota ◽  
Low Dose ◽  
Dextran Sulfate ◽  
Dextran Sulfate Sodium

Gut relief formula attenuates dextran sulfate sodium-induced colitis by regulating NF-κB signaling and the intestinal microbiota in mice

2021 ◽  
Author(s):  
Xuemeng Si ◽  
Ning Liu ◽  
Hai Jia ◽  
Jiaqi Wang ◽  
Lina Pan ◽  
...  
Keyword(s):  
Intestinal Microbiota ◽  
Dextran Sulfate ◽  
Dextran Sulfate Sodium ◽  
Mucosal Barrier ◽  
Mucosal Inflammation ◽  
Barrier Dysfunction

Gut relief formula administration alleviated mucosal inflammation and mucosal barrier dysfunction by inhibiting STAT3 and NF-κB activity and upregulating abundances of Lactobacillus in DSS-induced colitis.

Fungal–bacterial interactions in mice with dextran sulfate sodium (DSS)-induced acute and chronic colitis

RSC Advances ◽  
2016 ◽  
Vol 6 (70) ◽  
pp. 65995-66006 ◽  
Author(s):  
Xinyun Qiu ◽  
Xia Li ◽  
Zhe Wu ◽  
Feng Zhang ◽  
Ning Wang ◽  
...  
Keyword(s):  
Intestinal Microbiota ◽  
Inflammatory Bowel Diseases ◽  
Dextran Sulfate ◽  
Dextran Sulfate Sodium ◽  
Chronic Colitis ◽  
Bacterial Interactions ◽  
Bowel Diseases ◽  
Inflammatory Bowel

The commensal intestinal microbiota plays critical roles in the initiation and development of inflammatory bowel diseases (IBD).

scholarly journals Selenium-Enriched Lactobacillus acidophilus Ameliorates Dextran Sulfate Sodium-Induced Chronic Colitis in Mice by Regulating Inflammatory Cytokines and Intestinal Microbiota

2021 ◽  
Vol 8 ◽  
Author(s):  
Zeyu Wu ◽  
Dan Pan ◽  
Min Jiang ◽  
Lixuan Sang ◽  
Bing Chang
Keyword(s):  
Inflammatory Cytokines ◽  
Intestinal Microbiota ◽  
Relative Abundance ◽  
Lactobacillus Acidophilus ◽  
Dextran Sulfate ◽  
Dextran Sulfate Sodium ◽  
Activity Index ◽  
Disease Activity Index ◽  
Chronic Colitis ◽  
Group A

Aim: To evaluate the effect of Selenium-enriched Lactobacillus acidophilus (Se-enriched L. acidophilus) on dextran sulfate sodium (DSS)-induced colitis in mice.Methods: Mice were randomly divided into four groups: a control group, a control + Se-enriched L. acidophilus group, a chronic colitis group, and a chronic colitis + Se-enriched L. acidophilus group (n = 10 each group). The mice were sacrificed on the 26th day. The disease activity index, survival rates, and histological injury score were determined. Cytokines produced by lamina propria lymphocytes (LPLs), the selenium (Se) concentrations in serum and colon tissue and the mouse intestinal microbiota were evaluated.Results: Se-enriched L. acidophilus can improve histological injury and the disease activity index in mice with chronic colitis and reduce IL-1β, IL-6, IL-12p70, TNF-α, IL-23, IFN-γ, IL-17A, and IL-21 (P < 0.05) and increase IL-10 (P < 0.05) expression levels. Moreover, Se-enriched L. acidophilus can increase the β diversity of intestinal microbiota in mice with chronic colitis, significantly reduce the relative abundance of Lactobacillus and Romboutsia (P < 0.05), and significantly increase the relative abundance of Parasutterella (P < 0.05).Conclusions: Se-enriched L. acidophilus can improve DSS-induced chronic colitis by regulating inflammatory cytokines and intestinal microbiota.

Shikonin inhibits colitis-associated colorectal dysplasias in a mouse model of azoxymethane/dextran sulfate sodium colitis

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
JL Ríos ◽  
A Martí ◽  
I Andújar ◽  
RM Giner ◽  
MC Recio
Keyword(s):  
Mouse Model ◽  
Dextran Sulfate ◽  
Dextran Sulfate Sodium

Oral in vivo Bactofection in Dextran Sulfate Sodium Treated Female Wistar Rats

2010 ◽  
Vol 58 (3) ◽  
pp. 171-176 ◽  
Author(s):  
Roland Pálffy ◽  
Michal Behuliak ◽  
Roman Gardlík ◽  
Peter Jáni ◽  
L'udevít Kádaši ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Dextran Sulfate ◽  
Dextran Sulfate Sodium ◽  
Female Wistar Rats
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