Nontarget and Target Screening of Organohalogen Compounds in Mussels and Sediment from Hiroshima Bay, Japan: Occurrence of Novel Bioaccumulative Substances

2020 ◽  
Vol 54 (9) ◽  
pp. 5480-5488
Author(s):  
Akitoshi Goto ◽  
Nguyen Minh Tue ◽  
Tomohiko Isobe ◽  
Shin Takahashi ◽  
Shinsuke Tanabe ◽  
...  
Keyword(s):  
Organohalogen Compounds ◽  
Target Screening

Organohalogen compounds in human breast milk from Republic of Buryatia, Russia

2007 ◽  
Vol 146 (1) ◽  
pp. 225-232 ◽  
Author(s):  
Oyuna V. Tsydenova ◽  
Agus Sudaryanto ◽  
Natsuko Kajiwara ◽  
Tatsuya Kunisue ◽  
Valeriy B. Batoev ◽  
...  
Keyword(s):  
Breast Milk ◽  
Human Breast Milk ◽  
Human Breast ◽  
Organohalogen Compounds

scholarly journals Target screening of plant secondary metabolites in river waters by liquid chromatography coupled to high-resolution mass spectrometry (LC–HRMS)

2020 ◽  
Vol 32 (1) ◽  
Author(s):  
Mulatu Yohannes Nanusha ◽  
Martin Krauss ◽  
Carina D. Schönsee ◽  
Barbara F. Günthardt ◽  
Thomas D. Bucheli ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Surface Waters ◽  
High Resolution Mass Spectrometry ◽  
Water Cycle ◽  
Endocrine Disrupting Chemicals ◽  
Plant Secondary Metabolites ◽  
Biologically Active ◽  
Plant Metabolites ◽  
River Waters ◽  
Target Screening

Abstract Background Substantial efforts have been made to monitor potentially hazardous anthropogenic contaminants in surface waters while for plant secondary metabolites (PSMs) almost no data on occurrence in the water cycle are available. These metabolites enter river waters through various pathways such as leaching, surface run-off and rain sewers or input of litter from vegetation and might add to the biological activity of the chemical mixture. To reduce this data gap, we conducted a LC–HRMS target screening in river waters from two different catchments for 150 plant metabolites which were selected from a larger database considering their expected abundance in the vegetation, their potential mobility, persistence and toxicity in the water cycle and commercial availability of standards. Results The screening revealed the presence of 12 out of 150 possibly toxic PSMs including coumarins (bergapten, scopoletin, fraxidin, esculetin and psoralen), a flavonoid (formononetin) and alkaloids (lycorine and narciclasine). The compounds narciclasine and lycorine were detected at concentrations up to 3 µg/L while esculetin and fraxidin occurred at concentrations above 1 µg/L. Nine compounds occurred at concentrations above 0.1 µg/L, the Threshold for Toxicological Concern (TTC) for non-genotoxic and non-endocrine disrupting chemicals in drinking water. Conclusions Our study provides an overview of potentially biologically active PSMs in surface waters and recommends their consideration in monitoring and risk assessment of water resources. This is currently hampered by a lack of effect data including toxicity to aquatic organisms, endocrine disruption and genotoxicity and demands for involvement of these compounds in biotesting.

Suspect and target screening of emerging pesticides and their transformation products in an urban river using LC-QTOF-MS

2021 ◽  
pp. 147978
Author(s):  
Yangping Zhang ◽  
Haifeng Zhang ◽  
Juan Wang ◽  
Zhiyong Yu ◽  
Hongyan Li ◽  
...  
Keyword(s):  
Transformation Products ◽  
Urban River ◽  
Target Screening

Concomitant drug abuse of opioid dependent patients in maintenance treatment detected with a multi-target screening of oral fluid

2018 ◽  
Vol 27 (5) ◽  
pp. 407-412 ◽  
Author(s):  
Elias Wagner ◽  
Florian Raabe ◽  
Gabriele Martin ◽  
Catja Winter ◽  
Diana Plörer ◽  
...  
Keyword(s):  
Drug Abuse ◽  
Maintenance Treatment ◽  
Oral Fluid ◽  
Concomitant Drug ◽  
Target Screening

Volatile organohalogen compounds in human urine: The effect of environmental exposure

Chemosphere ◽  
2006 ◽  
Vol 62 (4) ◽  
pp. 626-640 ◽  
Author(s):  
Żaneta Polkowska ◽  
Katarzyna Kozłowska ◽  
Zofia Mazerska ◽  
Tadeusz Górecki ◽  
Jacek Namieśnik
Keyword(s):  
Environmental Exposure ◽  
Human Urine ◽  
Organohalogen Compounds ◽  
Volatile Organohalogen Compounds

Multi-target screening mines hesperidin as a multi-potent inhibitor: Implication in Alzheimer's disease therapeutics

2016 ◽  
Vol 121 ◽  
pp. 810-822 ◽  
Author(s):  
Sandipan Chakraborty ◽  
Jaya Bandyopadhyay ◽  
Sourav Chakraborty ◽  
Soumalee Basu
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Potent Inhibitor ◽  
Target Screening

Ein Datenbankmodell für aggregierte Non‐Target‐Screening‐Ergebnisse

Vom Wasser ◽  
2021 ◽  
Vol 119 (3) ◽  
pp. 94-96
Author(s):  
K. Jewell ◽  
F. Thron ◽  
M. Schlüsener ◽  
K. Kramer ◽  
T. Scharrenbach ◽  
...  
Keyword(s):  
Target Screening

Concentrations, Sources, and Risk Assessment of Organohalogen Compounds in Soils from Kiambu to Mombasa, Kenya

2018 ◽  
Vol 101 (6) ◽  
pp. 766-772 ◽  
Author(s):  
Victorine Anyango Makokha ◽  
Anne Wairimu Ndung’u ◽  
Teresiah Muciku Mungai ◽  
Xue Yan ◽  
Jun Wang
Keyword(s):  
Risk Assessment ◽  
Organohalogen Compounds
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