Adsorption of Human Serum Albumin on Graphene Oxide: Implications for Protein Corona Formation and Conformation

2018 ◽  
Vol 53 (15) ◽  
pp. 8631-8639 ◽  
Author(s):  
Xitong Liu ◽  
Chenxu Yan ◽  
Kai Loon Chen
Keyword(s):  
Graphene Oxide ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Protein Corona ◽  
Corona Formation

scholarly journals A study on human serum albumin corona formed on photoluminescent carbon dots

2020 ◽  
Vol 44 (7-8) ◽  
pp. 447-452
Author(s):  
Peng Wang ◽  
Ming Yuan ◽  
Na Li ◽  
Feng Zhang
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Carbon Dots ◽  
Resonance Energy ◽  
Binding Constants ◽  
Protein Corona ◽  
Hybrid Nanomaterial ◽  
Corona Formation ◽  
Biomedical Field

Fluorescence nanostructures have been widely applied in the biomedical field as therapeutic agents and as novel tools for labeling, imaging, and sensing. However, the protein corona will dramatically influence the predesigned properties of nanostructures in serum. Therefore, it is important to understand the mechanism of protein corona formation on nanostructures. Photoluminescent carbon dots have been widely applied in the biomedical field since their discovery. Due to the large overlap between the absorption spectra of proteins and the fluorescence spectra of photoluminescent carbon dots, herein we investigate the mechanism of human serum albumin corona formed on photoluminescent carbon dots using fluorescence resonance energy transfer. By employing spectroscopic methods, the binding constants and the number of binding sites between human serum albumin and photoluminescent carbon dots have been determined, and the corresponding thermodynamics are also discussed as well for the interaction between photoluminescent carbon dots and human serum albumin. In addition, we successfully demonstrate the photoluminescent carbon dots in labeling bean sprouts. We believe that the current research cannot shed light on the mechanism of protein corona formation on nanostructures, but also could benefit the design of hybrid nanomaterial which will be applied to serum environments.

Protein corona formation of human serum albumin with carbon quantum dots from roast salmon

2020 ◽  
Vol 11 (3) ◽  
pp. 2358-2367 ◽  
Author(s):  
Yukun Song ◽  
Haitao Wang ◽  
Lijuan Zhang ◽  
Bin Lai ◽  
Kangjing Liu ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Protein Corona ◽  
Carbon Quantum Dots ◽  
Corona Formation

Carbon quantum dots (CQDs) extracted from roast salmon could interact with human serum albumin (HSA) to form protein coronas, changing their biological identity.

Soft and Hard Interactions between Polystyrene Nanoplastics and Human Serum Albumin Protein Corona

2019 ◽  
Vol 30 (4) ◽  
pp. 1067-1076 ◽  
Author(s):  
Shinji Kihara ◽  
Nadine J. van der Heijden ◽  
Chris K. Seal ◽  
Jitendra P. Mata ◽  
Andrew E. Whitten ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Protein Corona

Multifunctional human serum albumin-modified reduced graphene oxide for targeted photothermal therapy of hepatocellular carcinoma

RSC Advances ◽  
2016 ◽  
Vol 6 (14) ◽  
pp. 11167-11175 ◽  
Author(s):  
Aixian Zheng ◽  
Da Zhang ◽  
Ming Wu ◽  
Huanghao Yang ◽  
Xiaolong Liu ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Graphene Oxide ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Reduced Graphene Oxide ◽  
Photothermal Therapy ◽  
Reduced Graphene ◽  
Nir Laser ◽  
Hcc Cells

Multifunctional human serum albumin-modified reduced graphene oxide can specifically target HCC cells and effectively kill them with the help of a NIR laser.

Human serum albumin stabilizes aqueous silver nanoparticle suspensions and inhibits particle uptake by cells

2018 ◽  
Vol 5 (4) ◽  
pp. 863-867 ◽  
Author(s):  
D. C. Kennedy ◽  
H. Qian ◽  
V. Gies ◽  
L. Yang
Keyword(s):  
Silver Nanoparticles ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Silver Nanoparticle ◽  
Protein Corona ◽  
Particle Uptake ◽  
Nanoparticle Suspensions ◽  
Commercial Polymers ◽  
Better Than

Human serum albumin forms a protein corona that stabilizes silver nanoparticles in water better than commercial polymers.

Molecularly Imprinted Nanogels Possessing Dansylamide Interaction Sites for Controlling Protein Corona In Situ by Cloaking Intrinsic Human Serum Albumin

Langmuir ◽  
2020 ◽  
Vol 36 (36) ◽  
pp. 10674-10682 ◽  
Author(s):  
Takahiro Morishita ◽  
Aoi Yoshida ◽  
Natsuki Hayakawa ◽  
Kentaro Kiguchi ◽  
Chehasan Cheubong ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Protein Corona ◽  
Molecularly Imprinted ◽  
Interaction Sites

Insights into graphene oxide interaction with human serum albumin in isolated state and in blood plasma

2021 ◽  
Vol 175 ◽  
pp. 19-29
Author(s):  
Stefka G. Taneva ◽  
Sashka Krumova ◽  
Ferenc Bogár ◽  
András Kincses ◽  
Svetozar Stoichev ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Blood Plasma ◽  
Human Serum ◽  
In Blood Plasma
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