Identification of Novel Perfluoroalkyl Ether Carboxylic Acids (PFECAs) and Sulfonic Acids (PFESAs) in Natural Waters Using Accurate Mass Time-of-Flight Mass Spectrometry (TOFMS)

2015 ◽  
Vol 49 (19) ◽  
pp. 11622-11630 ◽  
Author(s):  
Mark Strynar ◽  
Sonia Dagnino ◽  
Rebecca McMahen ◽  
Shuang Liang ◽  
Andrew Lindstrom ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Carboxylic Acids ◽  
Natural Waters ◽  
Time Of Flight ◽  
Accurate Mass ◽  
Sulfonic Acids ◽  
Flight Mass Spectrometry

scholarly journals An automated gas chromatography time-of-flight mass spectrometry instrument for the quantitative analysis of halocarbons in air

2016 ◽  
Vol 9 (1) ◽  
pp. 179-194 ◽  
Author(s):  
F. Obersteiner ◽  
H. Bönisch ◽  
A. Engel
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Quantitative Analysis ◽  
Time Of Flight ◽  
Resolving Power ◽  
Accurate Mass ◽  
Mass Spectrometry Instrument ◽  
Flight Mass Spectrometry ◽  
Mass Resolving Power ◽  
Mass Information

Abstract. We present the characterization and application of a new gas chromatography time-of-flight mass spectrometry instrument (GC-TOFMS) for the quantitative analysis of halocarbons in air samples. The setup comprises three fundamental enhancements compared to our earlier work (Hoker et al., 2015): (1) full automation, (2) a mass resolving power R = m/Δm of the TOFMS (Tofwerk AG, Switzerland) increased up to 4000 and (3) a fully accessible data format of the mass spectrometric data. Automation in combination with the accessible data allowed an in-depth characterization of the instrument. Mass accuracy was found to be approximately 5 ppm in mean after automatic recalibration of the mass axis in each measurement. A TOFMS configuration giving R = 3500 was chosen to provide an R-to-sensitivity ratio suitable for our purpose. Calculated detection limits are as low as a few femtograms by means of the accurate mass information. The precision for substance quantification was 0.15 % at the best for an individual measurement and in general mainly determined by the signal-to-noise ratio of the chromatographic peak. Detector non-linearity was found to be insignificant up to a mixing ratio of roughly 150 ppt at 0.5 L sampled volume. At higher concentrations, non-linearities of a few percent were observed (precision level: 0.2 %) but could be attributed to a potential source within the detection system. A straightforward correction for those non-linearities was applied in data processing, again by exploiting the accurate mass information. Based on the overall characterization results, the GC-TOFMS instrument was found to be very well suited for the task of quantitative halocarbon trace gas observation and a big step forward compared to scanning, quadrupole MS with low mass resolving power and a TOFMS technique reported to be non-linear and restricted by a small dynamical range.

Accurate mass analysis and structure elucidation of selenium metabolites by liquid chromatography electrospray time-of-flight mass spectrometry

2007 ◽  
Vol 22 (8) ◽  
pp. 947-959 ◽  
Author(s):  
Juan F. García-Reyes ◽  
Mihaly Dernovics ◽  
Pilar Ortega-Barrales ◽  
Amadeo R. Fernández-Alba ◽  
Antonio Molina-Díaz
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Structure Elucidation ◽  
Time Of Flight ◽  
Accurate Mass ◽  
Mass Analysis ◽  
Flight Mass Spectrometry ◽  
Accurate Mass Analysis
Sign in / Sign up

Export Citation Format

Share Document