Comprehensive Interrogation of Metabolic and Bioenergetic Responses of Early-Staged Zebrafish (Danio rerio) to a Commercial Copper Hydroxide Nanopesticide

2021 ◽  
Author(s):  
Xiaohong Wang ◽  
Yingju Qin ◽  
Xiaoyu Li ◽  
Bing Yan ◽  
Christopher J. Martyniuk
Keyword(s):  
Danio Rerio ◽  
Copper Hydroxide ◽  
Commercial Copper

Metabolomic and bioenergetic responses of human hepatocellular carcinoma cells following exposure to commercial copper hydroxide nanopesticide

2022 ◽  
Author(s):  
Xiaoyu Li ◽  
Yingju Qin ◽  
Long Kong ◽  
Xiliang Yan ◽  
Wei Zhang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Human Exposure ◽  
Cell Metabolism ◽  
Carcinoma Cells ◽  
Human Hepatocellular Carcinoma ◽  
Copper Hydroxide ◽  
Hepatocellular Carcinoma Cells ◽  
Commercial Copper ◽  
Exposure Risks ◽  
Human Hepatocellular Carcinoma Cells

Copper hydroxide (Cu(OH)2) nanopesticide formulas are becoming more frequently used in agriculture, however human exposure risks are not completely characterized. Here, the effect of Cu(OH)2 nanopesticide exposure on cell metabolism...

Local interaction rules and collective motion in black neon tetra (Hyphessobrycon herbertaxelrodi) and zebrafish (Danio rerio).

2019 ◽  
Vol 133 (2) ◽  
pp. 143-155 ◽  
Author(s):  
Vicenç Quera ◽  
Elisabet Gimeno ◽  
Francesc S. Beltran ◽  
Ruth Dolado
Keyword(s):  
Danio Rerio ◽  
Collective Motion ◽  
Local Interaction

Tris(pyrazolyl)borate Copper Hydroxide Complexes Featuring Tunable Intramolecular H-bonding

2019 ◽  
Author(s):  
Evan Gardner ◽  
Caitlyn Cobb ◽  
Jeffery A. Bertke ◽  
Timothy H. Warren
Keyword(s):  
Single Crystal ◽  
Copper Hydroxide ◽  
X Ray ◽  
Modular Synthesis ◽  
Pendant Arm ◽  
Copper Center ◽  
Vibrational Studies

A modular synthesis provides access to a series of new tris(pyrazolyl)borate ligands <sup>XpyMe</sup>TpK that possess a single functionalized pendant pyridyl (py) or pyrimidyl (pyd) arm designed to engage in tunable intramolecular H-bonding to metal–bound functionalities. To illustrate such H-bonding interactions, a series of [<sup>XpyMe</sup>TpCu]<sub>2</sub>(𝜇–OH)<sub>2</sub>(<b>6a</b><b>–6e</b>) complexes were synthesized from the corresponding <sup>XpyMe</sup>TpCu–OAc (<b>5a–5e</b>) complexes. Single crystal X-ray structures of three new dinuclear [<sup>XpyMe</sup>TpCu]<sub>2</sub>(𝜇–OH)<sub>2</sub>complexes reveal H-bonding between the pendant heterocycle and bridging hydroxide ligands while the donor arm engages the copper center in an unusual monomeric <sup>DMAPMe</sup>TpCu–OH complex. Vibrational studies (IR) of each bridging hydroxide complex reveal reduced 𝜈<sub>OH </sub>frequencies that tracks with the H-bond accepting ability of the pendant arm.

Tris(pyrazolyl)borate Copper Hydroxide Complexes Featuring Tunable Intramolecular H-bonding

2019 ◽  
Author(s):  
Evan Gardner ◽  
Caitlyn Cobb ◽  
Jeffery A. Bertke ◽  
Timothy H. Warren
Keyword(s):  
Single Crystal ◽  
Copper Hydroxide ◽  
X Ray ◽  
Modular Synthesis ◽  
Pendant Arm ◽  
Copper Center ◽  
Vibrational Studies

A modular synthesis provides access to a series of new tris(pyrazolyl)borate ligands <sup>XpyMe</sup>TpK that possess a single functionalized pendant pyridyl (py) or pyrimidyl (pyd) arm designed to engage in tunable intramolecular H-bonding to metal–bound functionalities. To illustrate such H-bonding interactions, a series of [<sup>XpyMe</sup>TpCu]<sub>2</sub>(𝜇–OH)<sub>2</sub>(<b>6a</b><b>–6e</b>) complexes were synthesized from the corresponding <sup>XpyMe</sup>TpCu–OAc (<b>5a–5e</b>) complexes. Single crystal X-ray structures of three new dinuclear [<sup>XpyMe</sup>TpCu]<sub>2</sub>(𝜇–OH)<sub>2</sub>complexes reveal H-bonding between the pendant heterocycle and bridging hydroxide ligands while the donor arm engages the copper center in an unusual monomeric <sup>DMAPMe</sup>TpCu–OH complex. Vibrational studies (IR) of each bridging hydroxide complex reveal reduced 𝜈<sub>OH </sub>frequencies that tracks with the H-bond accepting ability of the pendant arm.

Efektivitas Hipoglikemik Fraksi Etil Asetat Ampas Tahu menggunakan Model Hewan Ikan Zebra (Danio rerio)

2020 ◽  
Vol 5 (1) ◽  
pp. 16-21
Author(s):  
Nina Herlina ◽  
Mulyati ◽  
Yulianita ◽  
Putri Ananda
Keyword(s):  
Danio Rerio ◽  
Area Under Curve

Ampas tahu mengandung isoflavon genistein dan daidzein yang diduga memiliki efek hipoglikemik. Penelitian ini bertujuan untuk menguji efek hipoglikemik fraksi etil asetat ampas tahu (FEAAT). Ekstraksi isoflavon ampas tahu dilakukan dengan metode refluks menggunakan etanol dan HCl, kemudian fraksinasi menggunakan etil asetat. Efek hipoglikemik FEAAT dibuktikan menggunakan ikan zebra sebagai hewan uji. Kelompok perlakuan terdiri dari kontrol negatif (akuades), FEAAT1 dan FEAAT2 dengan konsentrasi 3,75% dan 5% serta kontrol positif (metformin). Hiperglikemia diinduksi dengan perendaman menggunakan aloksan 0,05% selama 30 menit, glukosa 1% selama 30 menit. Selanjutnya dilakukan pemberian sampel uji selama 120 menit secara berurutan untuk menguji efek hipoglikemik dari sampel uji. Cuplikan darah diambil pada menit ke-0, 30, 60, 90, dan 120 untuk diuji kadar glukosa darah. Hasil uji menunjukkan bahwa terdapat perbedaan yang nyata pada luas Area Under Curve (AUC0-120) kontrol negatif dengan FEAAT2 dan metformin (p < 0,01). Sementara hasil nilai AUC0-120 FEAAT1 tidak berbeda nyata dengan kontrol negatif. FEAAT2 efektif sebagai agen hipoglikemik pada model hewan ikan zebra yang diinduksi hiperglikemik.

MONITORING BEHAVIORAL RESPONSES OF ZEBRAFISH (Danio rerio) AS A BIOMARKER FOR IDENTIFYING CADMIUM AND DELTAMETHRIN IN WATER

2016 ◽  
Vol 15 (10) ◽  
pp. 2171-2179 ◽  
Author(s):  
Jin-Song Zhang ◽  
Yi Huang ◽  
Xiao-Bo Han ◽  
Ting-Lin Huang ◽  
Alice K. Y. Chan
Keyword(s):  
Danio Rerio ◽  
Behavioral Responses
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