A Bad Start in Life? Maternal Transfer of Legacy and Emerging Poly- and Perfluoroalkyl Substances to Eggs in an Arctic Seabird

2021 ◽  
Author(s):  
William Jouanneau ◽  
Don-Jean Léandri-Breton ◽  
Alexandre Corbeau ◽  
Dorte Herzke ◽  
Børge Moe ◽  
...  
Keyword(s):  
Perfluoroalkyl Substances ◽  
Maternal Transfer

Maternal transfer of perfluoroalkyl substances in hooded seals

2016 ◽  
Vol 36 (3) ◽  
pp. 763-770 ◽  
Author(s):  
Randi Grønnestad ◽  
Gro D. Villanger ◽  
Anuschka Polder ◽  
Kit M. Kovacs ◽  
Christian Lydersen ◽  
...  
Keyword(s):  
Perfluoroalkyl Substances ◽  
Maternal Transfer

Thermal stability and decomposition of perfluoroalkyl substances on spent granular activated carbon

2020 ◽  
Author(s):  
Feng Xiao ◽  
Bin Yao ◽  
Pavankumar Challa Sasi ◽  
Svetlana Golovko ◽  
Dana Soli ◽  
...  
Keyword(s):  
Thermal Stability ◽  
Activated Carbon ◽  
Granular Activated Carbon ◽  
Perfluoroalkyl Substances

Maternal Perfluoroalkyl Substances, Thyroid Hormones, and DIO Genes: A Spanish Cross-sectional Study

2021 ◽  
Author(s):  
Blanca Sarzo ◽  
Virginia Ballesteros ◽  
Carmen Iñiguez ◽  
Cyntia B. Manzano-Salgado ◽  
Maribel Casas ◽  
...  
Keyword(s):  
Thyroid Hormones ◽  
Cross Sectional Study ◽  
Perfluoroalkyl Substances ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Exposure to perfluoroalkyl substances (PFAS) and dyslipidemia, hypertension and obesity in adolescents. The Fit Futures study

2021 ◽  
Vol 195 ◽  
pp. 110740
Author(s):  
Maria Averina ◽  
Jan Brox ◽  
Sandra Huber ◽  
Anne-Sofie Furberg
Keyword(s):  
Perfluoroalkyl Substances

scholarly journals Perfluoroalkyl substances and lipid profile in exposed pregnant women in the Veneto Region, Italy

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
T Dalla Zuanna ◽  
G Barbieri ◽  
G Pitter ◽  
M Zare Jeddi ◽  
F Daprà ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Lipid Profile ◽  
Plasma Concentrations ◽  
Density Lipoprotein ◽  
Additive Models ◽  
Lipoprotein Cholesterol ◽  
Perfluoroalkyl Substances ◽  
Surveillance Program ◽  
Veneto Region ◽  
Exposed Population

Abstract Background Perfluoroalkyl substances (PFASs) are persistent and widespread environmental pollutants. Residents of a large area of the Veneto Region (North-Eastern Italy) were exposed to high concentrations of PFASs through drinking water from the late-1970s to 2013. PFASs have been consistently associated with raised serum lipids, but only few studies have been conducted among pregnant women, and none has stratified analyses by trimesters of gestation. Our main objective was to evaluate the association between perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) levels and lipid profiles in high-exposed pregnant women. Methods A cross-sectional analysis was conducted in 319 pregnant women (age 14-48 years) recruited in the Regional health surveillance program. Serum PFASs were measured by HPLC-MS/MS. Non-fasting serum total cholesterol (TC) and high-density lipoprotein cholesterol (HDL-C) were measured by enzymatic assays in automated analysers, and low-density lipoprotein cholesterol (LDL-C) was calculated. The associations between ln-transformed PFASs (and categorized into quartiles) and lipids were assessed using generalized additive models. Analyses were adjusted for potential confounders and stratified according to pregnancy trimester. Results In the first trimester, plasma concentrations of both PFOA and PFOS were positively associated with TC. However in the third trimester PFOA levels were instead inversely significantly associated with TC and LDL-C levels. Overall, both PFOA and PFOS were positively associated with HDL-C, and PFOA negatively with LDL-C. Conclusions In a small highly exposed population of pregnant women, the associations between PFASs concentrations and lipid profile were modified by trimester of gestation. Patterns late in pregnancy were different to the positive associations with LDL-C generally found. Differential transfer and bioaccumulation of lipids and PFAS in the placenta across gestation might explain our findings. Key messages This study provides evidence of different patterns of PFAS associations with lipids in pregnant women across the trimesters of gestation. The different patterns of association from general population studies sheds light on the role of fetal nutrition during pregnancy affecting both lipids and PFAS in serum.

Suspect and Nontarget Screening Revealed Class-Specific Temporal Trends (2000–2017) of Poly- and Perfluoroalkyl Substances in St. Lawrence Beluga Whales

2021 ◽  
Vol 55 (3) ◽  
pp. 1659-1671
Author(s):  
Holly Barrett ◽  
Xuan Du ◽  
Magali Houde ◽  
Stéphane Lair ◽  
Jonathan Verreault ◽  
...  
Keyword(s):  
Temporal Trends ◽  
Perfluoroalkyl Substances ◽  
Beluga Whales ◽  
Nontarget Screening
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