Nonalcoholic Fatty Liver Disease Development in Zebrafish upon Exposure to Bis(2-ethylhexyl)-2,3,4,5-tetrabromophthalate, a Novel Brominated Flame Retardant

2021 ◽  
Author(s):  
Wei Guo ◽  
Lei Lei ◽  
Xiongjie Shi ◽  
Ruiwen Li ◽  
Qiangwei Wang ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Flame Retardant ◽  
Nonalcoholic Fatty Liver Disease ◽  
Fatty Liver Disease ◽  
Disease Development ◽  
Brominated Flame Retardant ◽  
Nonalcoholic Fatty Liver

scholarly journals Targeted Nutrient Modifications in Purified Diets Differentially Affect Nonalcoholic Fatty Liver Disease and Metabolic Disease Development in Rodent Models

2020 ◽  
Vol 4 (6) ◽  
Author(s):  
Sridhar Radhakrishnan ◽  
Jia-Yu Ke ◽  
Michael A Pellizzon
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Fatty Liver Disease ◽  
Metabolic Diseases ◽  
Complex Spectrum ◽  
Disease Development ◽  
Rodent Models ◽  
Nonalcoholic Fatty Liver ◽  
Time Frames

ABSTRACT Nonalcoholic fatty liver disease (NAFLD) is a complex spectrum of disorders ranging from simple benign steatosis to more aggressive forms of nonalcoholic steatohepatitis (NASH) and fibrosis. Although not every patient with NAFLD/NASH develops liver complications, if left untreated it may eventually lead to cirrhosis and hepatocellular carcinoma. Purified diets formulated with specific nutritional components can drive the entire spectrum of NAFLD in rodent models. Although they may not perfectly replicate the clinical and histological features of human NAFLD, they provide a model to gain further understanding of disease progression in humans. Owing to the growing demand of diets for NAFLD research, and for our further understanding of how manipulation of dietary components can alter disease development, we outlined several commonly used dietary approaches for rodent models, including mice, rats, and hamsters, time frames required for disease development and whether other metabolic diseases commonly associated with NAFLD in humans occur.

scholarly journals Lowering the dietary omega-6: omega-3 does not hinder nonalcoholic fatty-liver disease development in a murine model

2015 ◽  
Vol 35 (5) ◽  
pp. 449-459 ◽  
Author(s):  
Reilly T. Enos ◽  
Kandy T. Velázquez ◽  
Jamie L. McClellan ◽  
Taryn L. Cranford ◽  
Michael D. Walla ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Murine Model ◽  
Fatty Liver Disease ◽  
Disease Development ◽  
Omega 3 ◽  
Nonalcoholic Fatty Liver ◽  
Omega 6

scholarly journals Author Correction: The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Sophie Cazanave ◽  
Alexei Podtelezhnikov ◽  
Kristian Jensen ◽  
Mulugeta Seneshaw ◽  
Divya P. Kumar ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Fatty Liver Disease ◽  
Disease Development ◽  
Nonalcoholic Fatty Liver ◽  
Transcriptomic Signature

scholarly journals The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Sophie Cazanave ◽  
Alexei Podtelezhnikov ◽  
Kristian Jensen ◽  
Mulugeta Seneshaw ◽  
Divya P. Kumar ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Fatty Liver Disease ◽  
Disease Development ◽  
Nonalcoholic Fatty Liver ◽  
Transcriptomic Signature
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