Abiotic Transformation of Lamotrigine by Redox-Active Mineral and Phenolic Compounds

2021 ◽  
Vol 55 (3) ◽  
pp. 1535-1544
Author(s):  
Marina Karpov ◽  
Bettina Seiwert ◽  
Vered Mordehay ◽  
Thorsten Reemtsma ◽  
Tamara Polubesova ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Redox Active ◽  
Abiotic Transformation

Common modifications of selenocysteine in selenoproteins

2019 ◽  
Vol 64 (1) ◽  
pp. 45-53 ◽  
Author(s):  
Elias S.J. Arnér
Keyword(s):  
Amino Acids ◽  
Covalent Binding ◽  
Physicochemical Characteristics ◽  
Redox Active

Abstract Selenocysteine (Sec), the sulfur-to-selenium substituted variant of cysteine (Cys), is the defining entity of selenoproteins. These are naturally expressed in many diverse organisms and constitute a unique class of proteins. As a result of the physicochemical characteristics of selenium when compared with sulfur, Sec is typically more reactive than Cys while participating in similar reactions, and there are also some qualitative differences in the reactivities between the two amino acids. This minireview discusses the types of modifications of Sec in selenoproteins that have thus far been experimentally validated. These modifications include direct covalent binding through the Se atom of Sec to other chalcogen atoms (S, O and Se) as present in redox active molecular motifs, derivatization of Sec via the direct covalent binding to non-chalcogen elements (Ni, Mb, N, Au and C), and the loss of Se from Sec resulting in formation of dehydroalanine. To understand the nature of these Sec modifications is crucial for an understanding of selenoprotein reactivities in biological, physiological and pathophysiological contexts.

Alkaloids and phenolic compounds from Acronychia laurifolia

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
E Kouloura ◽  
M Halabalaki ◽  
MC Lallemand ◽  
F Tillequin ◽  
AL Skaltsounis
Keyword(s):  
Phenolic Compounds

Antioxidant phenolic compounds from Sedum dasyphyllum L.

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
D van Diermen ◽  
M Pierreclos ◽  
K Hostettmann
Keyword(s):  
Phenolic Compounds

Medicinal preparations on the basis of vegetable phenolic compounds

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
E Kemertelidze ◽  
M Alania ◽  
T Sagareishvili ◽  
K Shalashvili ◽  
N Kavtaradze
Keyword(s):  
Phenolic Compounds ◽  
Medicinal Preparations
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