Temperature-Sensitive Polymersomes for Controlled Delivery of Anticancer Drugs

2015 ◽  
Vol 27 (23) ◽  
pp. 7945-7956 ◽  
Author(s):  
Fei Liu ◽  
Veronika Kozlovskaya ◽  
Srikanth Medipelli ◽  
Bing Xue ◽  
Fahim Ahmad ◽  
...  
Keyword(s):  
Anticancer Drugs ◽  
Controlled Delivery ◽  
Temperature Sensitive

Functionalized Ultrasmall Fluorinated Graphene with High NIR Absorbance for Controlled Delivery of Mixed Anticancer Drugs

2017 ◽  
Vol 23 (69) ◽  
pp. 17531-17541 ◽  
Author(s):  
Peiwei Gong ◽  
Qiao Zhao ◽  
Dujuan Dai ◽  
Shumiao Zhang ◽  
Zhenzhen Tian ◽  
...  
Keyword(s):  
Anticancer Drugs ◽  
Controlled Delivery ◽  
Fluorinated Graphene

Organic-inorganic hybrid nanoparticles controlled delivery system for anticancer drugs

2017 ◽  
Vol 526 (1-2) ◽  
pp. 380-390 ◽  
Author(s):  
Antonio Di Martino ◽  
Olga A. Guselnikova ◽  
Marina E. Trusova ◽  
Pavel S. Postnikov ◽  
Vladimir Sedlarik
Keyword(s):  
Anticancer Drugs ◽  
Delivery System ◽  
Controlled Delivery ◽  
Hybrid Nanoparticles ◽  
Inorganic Hybrid

Efficient Wormlike Micelles for the Controlled Delivery of Anticancer Drugs

2020 ◽  
Vol 10 ◽  
Author(s):  
P. Sharmiladevi ◽  
M. Breghatha ◽  
K. Dhanavardhini ◽  
R. Priya ◽  
Koyeli Girigoswami ◽  
...  
Keyword(s):  
Anticancer Drugs ◽  
Sodium Salicylate ◽  
Controlled Delivery ◽  
Self Organization ◽  
Wormlike Micelles ◽  
Delivery Vehicle ◽  
Killing Effect ◽  
Salicylate Concentration ◽  
Doxorubicin Release ◽  
Cell Killing Effect

Background: In order to improve the solubility and carrying capacity of anticancer drugs to the targeted cells a potential nanoformulation is needed Objective: A viscoelastic wormlike micelles (WLM) have been reported in the present study. Methods: The elongated and flexible aggregates of amphiphiles were formed due to the self-organization when the amphiphile concentration was fixed at its CMC and the sodium salicylate concentration was varied for the optimization Results: The stable structure, higher density, higher viscosity and potent cell killing effect at lower concentration of drug were observed at 480 μM concentration of sodium salicylate. The doxorubicin release profile showed a clear sustained release after 20 h and 82% of the drug has been released after 72 h. Conclusion: Therefore, the designed WLMs can be used as efficient drug delivery vehicle for the treatment of cancer

Polyethylene glycol–gum acacia-based multidrug delivery system for controlled delivery of anticancer drugs

2018 ◽  
Vol 76 (10) ◽  
pp. 5011-5037 ◽  
Author(s):  
V. O. Fasiku ◽  
B. A. Aderibigbe ◽  
E. R. Sadiku ◽  
Y. Lemmer ◽  
S. J. Owonubi ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
Anticancer Drugs ◽  
Delivery System ◽  
Controlled Delivery ◽  
Gum Acacia

scholarly journals Crosslinked multilamellar liposomes for controlled delivery of anticancer drugs

Biomaterials ◽  
2013 ◽  
Vol 34 (12) ◽  
pp. 3098-3109 ◽  
Author(s):  
Kye-Il Joo ◽  
Liang Xiao ◽  
Shuanglong Liu ◽  
Yarong Liu ◽  
Chi-Lin Lee ◽  
...  
Keyword(s):  
Anticancer Drugs ◽  
Controlled Delivery ◽  
Multilamellar Liposomes

Abstract 3686: Engineering nanoparticles of polymalic acid for controlled delivery of anticancer drugs

2015 ◽  
Author(s):  
José Antonio Portilla-Arias ◽  
Alberto Lanz-Landazuri ◽  
Montserrat Garcia-Alvarez ◽  
Antxon Martinez de Ilarduia ◽  
Rameshwar Patil ◽  
...  
Keyword(s):  
Anticancer Drugs ◽  
Controlled Delivery ◽  
Polymalic Acid

Controlled Delivery and Reduced Side Effects of Anticancer Drugs Complexed with Polymeric Nanocarrier

2021 ◽  
pp. 119-147
Author(s):  
Lesya Kobylinska ◽  
Nataliya Mitina ◽  
Alexander Zaichenko ◽  
Rostyslav Stoika
Keyword(s):  
Side Effects ◽  
Anticancer Drugs ◽  
Controlled Delivery ◽  
Polymeric Nanocarrier

Electrospun nanofibers incorporating self-decomposable silica nanoparticles as carriers for controlled delivery of anticancer drug

RSC Advances ◽  
2015 ◽  
Vol 5 (81) ◽  
pp. 65897-65904 ◽  
Author(s):  
Xiaojun Zhou ◽  
Liang Chen ◽  
Weizhong Wang ◽  
Yating Jia ◽  
Anni Chang ◽  
...  
Keyword(s):  
Silica Nanoparticles ◽  
Anticancer Drugs ◽  
Anticancer Drug ◽  
Electrospun Nanofibers ◽  
Silica Nanoparticle ◽  
Controlled Delivery

A decomposable silica nanoparticle-incorporated electrospun mat as a carrier for anticancer drugs.

scholarly journals Morphology of the Micelles Formed by a Comb-Like PEG-Containing Copolymer Loaded with Antitumor Substances with Different Water Solubilities

2020 ◽  
Vol 65 (8) ◽  
pp. 670
Author(s):  
N. Ye. Mitina ◽  
A. O. Riabtseva ◽  
V. M. Garamus ◽  
R. B. Lesyk ◽  
K. A. Volyanyuk ◽  
...  
Keyword(s):  
Anticancer Drugs ◽  
Structural Changes ◽  
Amphiphilic Polymers ◽  
Water Soluble ◽  
Controlled Delivery ◽  
Supramolecular Complexes ◽  
Antitumor Antibiotic ◽  
Drug Solubility ◽  
Solubility In Water ◽  
Derivatives Of

The controlled delivery of anticancer drugs is driven by their interaction with carrier molecules. By creating complicated micelle-like complexes, amphiphilic polymers provide an opportunity to load drugs of various kinds. In this work, the interaction of the comb-like PEG-containing polymer poly(VEP-co-GMA)-graft-PEG with the water-soluble antitumor antibiotic doxorubicin and new water-insoluble derivatives of thiozalidinone Les-3883 characterized by a high anticancer efficiency has been studied in aqueous solutions by means of the SAXS, DLS, TEM, and photoluminescence methods. The formation of polymer micelles and their complexes with drugs, as well as their structural changes, is observed. The obtained results give evidence that the mechanism of organization of supramolecular complexes depends on the drug solubility in water. A potential capability of poly(VEP-co-GMA)-graft-PEG to prolong the drug circulation lifetime is confirmed.

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